Patents by Inventor Jorn L. M. Buus

Jorn L. M. Buus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4384140
    Abstract: The present invention relates to novel aminoalkyl substituted nitrosourea derivatives as well as their acid addition salts with pharmaceutically acceptable acids showing pronounced antineoplastic effectiveness in animal experiments.The novel compounds of the present invention may be represented by the following formula: ##STR1## wherein X and Y are the same or different, and are selected from the group consisting of a phenyl group and a cyclohexyl group, said phenyl and cyclohexyl groups being optionally substituted with one or two substituents selected from a halogen atom, a lower alkyl group having from one to four carbon atoms inclusive, a trifluore methyl group, a cyano group, a phenyl group, a cyclohexyl group and a lower alkyloxy group having from one to four carbon atoms inclusive."Alkylene" is an alkylene group, branched or unbranched, having from one to four carbon atoms inclusive, and R.sup.1 and R.sup.
    Type: Grant
    Filed: February 16, 1982
    Date of Patent: May 17, 1983
    Assignee: Kefalas A/S
    Inventors: Peter Bregnedal, Jorn L. M. Buus
  • Patent number: 4309429
    Abstract: The present invention relates to novel thioxanthene and xanthene derivatives which have useful pharmacodynamic activity, such as neuroleptic activity and antiemetic activity, methods for the preparation of said derivatives, pharmaceutical compositions containing same, and a method for the treatment of psychic disorders by administering a therapeutically active amount of one of said derivatives to a living animal body, including human beings.
    Type: Grant
    Filed: December 21, 1979
    Date of Patent: January 5, 1982
    Assignee: Kefalas A/S
    Inventors: Niels Lassen, Klaus P. Bogeso, Peter B. Hansen, Jorn L. M. Buus, Allan J. Bigler
  • Patent number: 4285956
    Abstract: The present invention relates to novel thioxanthene and xanthene derivatives which have useful pharmacodynamic activity, such as neuroleptic activity and antiemetic activity, methods for the preparation of said derivatives, pharmaceutical compositions containing same, and a method for the treatment of psychic disorders by administering a therapeutically active amount of one of said derivatives to a living animal body, including human beings.
    Type: Grant
    Filed: May 3, 1979
    Date of Patent: August 25, 1981
    Assignee: Kefalas A/S
    Inventors: Niels Lassen, Klaus P. Boges, Peter B. Hansen, Jorn L. M. Buus, Allan J. Bigler
  • Patent number: 4275209
    Abstract: The present invention relates to novel thioxanthene and xanthene derivatives which have useful pharmacodynamic activity, such as neuroleptic activity and antiemetic activity, methods for the preparation of said derivatives, pharmaceutical compositions containing same, and a method for the treatment of psychic disorders by administering a therapeutically active amount of one of said derivatives to a living animal body, including human beings.
    Type: Grant
    Filed: December 21, 1979
    Date of Patent: June 23, 1981
    Assignee: Kefalas A/S
    Inventors: Niels Lassen, Klaus P. Bogeso, Peter B. Hansen, Jorn L. M. Buus, Allan J. Bigler
  • Patent number: 4153694
    Abstract: The present invention relates to novel behenic acid esters of the following general formula: ##STR1## wherein X is "N" or "CH," the non-toxic acid addition salts thereof, a method for the preparation of said esters and therapeutic compositions thereof having prolonged effect.It is an object of the present invention to provide behenic acid esters of Formula I, a method of making the same, a method for the alleviation, palliation, mitigation or inhibition of the manifestations of certain physiological-psychological abnormalities of animals therewith, and pharmaceutical compositions comprising such compounds as active ingredient.Other objects will be apparent to one skilled in the art and still other objects will become apparent hereinafter.
    Type: Grant
    Filed: August 19, 1977
    Date of Patent: May 8, 1979
    Assignee: Kefalas A/S
    Inventors: Jorn L. M. Buus, Niels Lassen