Abstract: A mobile kit for imaging microscopic organisms in a liquid sample, comprises a slide having a liquid sample chamber with a liquid sample inlet, and a slide reader containing a lens and configured to receive the slide and image the liquid sample chamber through the lens using a mobile imaging device that is coupled to the slide reader. The liquid sample chamber of the slide is a linear elongated liquid sample chamber, and the slide reader comprises a track configured to receive the slide and guide movement of the slide along the track allowing the length of the linear elongated liquid sample chamber to be imaged through the lens and a drive module configured to move the slide along the track.

Abstract: The present disclosure provides methods and compositions useful for generating cellular models of VWF disease from human pluripotent stem cells. In one aspect, the present disclosure relates to a method for the generation of an in vitro cellular model of VWF disease comprising VWF disease-relevant endothelial cells derived from human pluripotent stem cells (hPSCs). In an embodiment, the human pluripotent stem cells (hPSCs) are treated with an agent effective in suppressing or deleting at least one gene sequence encoding a protein and/or a subunit thereof, where the protein and/or subunit thereof is associated with VWF-linked secretion. The present disclosure also provides uses of the cellular models disclosed herein.

Abstract: A polycrystalline magnetocaloric material based on thermally annealed Fe100-xRhx melt-spun ribbons with chemical composition x in the interval 48?x?52 at. % and the bcc CsCl-type crystal structure (B2) and method for manufacturing the same. The material has improved magnetocaloric properties associated to first-order magneto-elastic phase transition compared to bulk alloys of similar chemical composition manufactured by conventional melting techniques; exhibiting both low-magnetic field induced giant magnetocaloric effects and enhanced refrigeration capacity close to the room temperature range, due to the fast increase of a magnetic entropy change at low fields that is followed by a broad table-like magnetic entropy change as function in the temperature curve.

Abstract: It is the object of the present invention to provide a mobile platform that allows the execution of physical stimulation and rehabilitation exercises through augmented reality games, of simple preparation and configuration, adaptable to various spaces and operating conditions. For this purpose, the platform comprises a sensory unit (2) and a projection unit (5), which are controlled by a processing unit (4). All these units are integrated in a mobile base (9), to allow the displacement of the platform. This also comprises a rotating joint (7) and an articulated arm (8) to allow the projection of games on the floor or on the wall.

Abstract: This invention relates to the field of primary immunodeficiencies (PID), more specifically to means and method for the diagnosis of PID of the lymphoid system. Provided are unique reagent compositions for the flow cytometric immunophenotyping of leukocytes comprising fluorochrome-conjugated antibodies directed against various specific combinations of markers. Also provided are kits comprising the reagent compositions, and methods using the same.

Abstract: A cooling/heating method including the application and removal of a pressurising gas on a hybrid organic-inorganic porous material (MOF) whereby a breathing transition is produced. In this transition, a change in volume in the structure of the compound occurs when its pores open/close, together with adsorption/desorption of a gas after applying and removing a pressurising gas on the compound; and breathing which occurs at temperatures close to ambient temperature (from ?20° C. to 60° C.) and at low pressures (from 10?5 bar up to 50 bar) and with great isothermal entropy changes (>100 J K?1 kg?1). A cooling/heating device comprising the hybrid materials defined above.

Abstract: The present invention relates to the field of washing machines, in particular a domestic washing machine, keeping in mind that the objects to be washed are of different nature, manufacture, materials, geometry and volume, in addition to having different types and levels of dirt.

Abstract: A self-reconfigurable controller for a robot, including: input/output (I/O) interfaces to enable communication with I/O peripheral devices coupled to the robot; and processing circuitry that is operable to: register the I/O peripheral devices and associated functionalities; receive a command for the robot to perform a task; conduct a self-awareness check to correlate functionalities to perform the task with functionalities of the I/O peripheral devices; and generate, based on a net of deep learning (DL) models and a result of the correlation, a target deep learning controller (TDLC) model to control the robot to perform the task.

Abstract: A semi-submersible floating platform including six columns (CV, CL) arranged forming a triangle such that three vertex columns (CV) are arranged at the vertices of the triangle. Three side columns (CL) are arranged at the centers of the sides of the triangle. Each column (CV, CL) is connected by a joining element (B) respective to each of the adjacent columns (CV, CL). Further, a side column (CL) is configured to support the wind turbine (A). The columns (CV, CL) that do not support the wind turbine (A) have a weight configured to maintain the center of mass of the set formed by the platform (1) and wind turbine (A) in the vertical of the hull center of the platform (1).

Abstract: The disclosure is generally directed to in-vehicle entertainment systems and methods. An example method executed by processor of a vehicle may include displaying an iconic representation containing a first icon representing a musical instrument and a second icon representing a vehicle component. The processor may detect an assigning of the musical instrument to the vehicle component. The assigning may be carried out, for example, by a driver of the vehicle executing a drag-and-operation to overlap the first icon with second icon. The processor may then detect a physical contact made upon the vehicle component and generate, based on detecting the physical contact, a musical sound corresponding to the musical instrument.

Abstract: Embodiments described herein address the problem of treating or ameliorating fungal infections and biofilm formation, and in particular Candida infection. Certain aspects are directed to anti-fungal compounds and compositions.

Abstract: Aspects of the present disclosure relate to data management of event representations within a discoverable event stream. These techniques may include determining historical query information based upon historical execution of a query over an event stream, and identifying a storage attribute of data associated with the historical execution of the query over the event stream, the storage attribute indicating at least one of a size of the data or an assigned storage location of the data in a first storage location or a second storage location. In addition, the techniques may include identifying an execution attribute of a future execution the query over the event stream, and modifying the assigned storage location of the data based on the historical query information, the storage attribute, and the execution attribute.

Abstract: Aspects of the present disclosure relate to ingesting event data into a discoverable event stream using a common schema to assign timeseries properties to the event data. These techniques may include receiving a first event of a pre-processed event stream, the first event including a plurality of event data fields representing an occurrence of the first event, and determining timing information based on the plurality of event data fields representing the occurrence of the first event. In addition, the techniques may include generating, based on combining the plurality of event data fields and the timing information, a second event of a discoverable event stream corresponding to the pre-processed event stream, and generating, within a time series of the discoverable event stream, based on the timing information and an event field of the plurality of event data fields, a time series entry corresponding to the second event.

Abstract: Methods, apparatus, systems, and articles of manufacture for real-time voice type detection in audio data are disclosed. An example non-transitory computer-readable medium disclosed herein includes instructions, which when executed, cause one or more processors to at least identify a first vocal effort of a first audio segment of first audio data and a second vocal effort of a second audio segment of the first audio data, train a neural network including training data, the training data including the first vocal effort, the first audio segment, the second audio segment, and the second vocal effort, and deploy the neural network, the neural network to distinguish between the first vocal effort and the second vocal effort.

Abstract: Aspects of the present disclosure relate to view management in a discoverable event streams. These techniques may include receiving a first event of a discoverable event stream, the first event including a plurality of event data fields representing an occurrence of the first event, and identifying a discoverable event stream view associated with an event data field of the plurality of event data field. The techniques may further include generating, based on application of a modification to or computation on the event data field, a second event of the discoverable event stream view.

Abstract: Described are examples for managing event data from multiple event data sources including executing, by a processor, a query for event data in a discoverable event stream over a time window that includes a delay tolerance window specific to the query, wherein the event data is stored as timeseries data in the discoverable event stream such that at least one property corresponding to at least one object has multiple different values at multiple different time instances, and wherein the delay tolerance window is configured to capture potentially out-of-order event data or late arriving event data, and returning a subset of multiple different values for the at least one property in instances of the event data corresponding to the time window with the delay tolerance window applied for the query.

Abstract: FoxO inhibitors for use in the treatment of diseases caused by abnormal TDP-43 and/or FUS proteins. The present invention refers to FoxO inhibitors, preferably quinolone derivatives, for use in the treatment of diseases caused by alterations of TDP-43 and/or FUS proteins, preferably Amyotrophic lateral sclerosis (ALS).

Abstract: The present invention relates to 1,2-dihydroquinoline-2-ones of formula (I): or a pharmaceutically acceptable salt or solvate thereof, for its use in the treatment of limb girdle muscular dystrophy.

Abstract: Various systems and methods are provided for a biased cathode assembly of an X-ray tube with improved thermal management and a method of manufacturing same. In one example, a cathode assembly of an X-ray tube comprises an emitter assembly including an emitter coupled to an emitter support structure, and an electrode assembly including an electrode stack and a plurality of bias electrodes. The emitter assembly including a plurality of independent components that are coupled together. The electrode assembly including a plurality of independent components that are coupled together, and the emitter assembly being coupled to the electrode assembly.

Abstract: Methods and apparatuses for implementing a neural network using symmetric tensors. In embodiments, a system may include a higher order neural network with a plurality of layers that includes an input layer, one or more hidden layers, and an output layer. Each of the input layer, the one or more hidden layers, and the output layer includes a plurality of neurons, where the plurality of neurons includes at least first order neurons and second order neurons, and where inputs at a second order neuron are combined using a symmetric tensor.