Abstract: The present invention concerns a method for preventing, modulating or curing in a mammal, the infections with Helicobacter pylori or the symptoms associated with H. pylori infection(s) or related diseases, and/or improving the clinical condition of a mammal infected with H. pylori, or affected by a related disease, comprising administering to a mammal in need thereof an effective amount of one or more DHA related compounds, as well as their use as an adjuvant or co-adjuvant in a method for preventing, modulating or curing in a mammal, the chronical infection with Helicobacter pylori or the symptoms associated with H. pylori infection or related diseases, and/or preventing recurrence as well as relapse of H. pylori infection or related diseases, and/or improving the clinical condition of a mammal infected with H. pylori.