Patents by Inventor José Carlos Prados Salazar

José Carlos Prados Salazar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ETHANOLIC EXTRACT OF SEEDS OF SOLANUM MELONGENA, METHOD FOR OBTAINING IT, PHARMACEUTICAL COMPOSITION CONTAINING IT AND USE THEREOF AS AN ANTITUMOUR AGENT
    Publication number: 20230414692
    Abstract: The present invention provides a method for obtaining an ethanolic extract from mature seeds of Solanum melongena, preferably defatted, characterized in that they are extracted with a hydroalcoholic solution containing 50% ethanol, at acid PH, preferably under a nitrogen atmosphere and for short periods of time, no longer than 1-2 h. The extracts obtained from different varieties of Solanum melongena have a high polyphenol content and show potent antitumor activity against colon adenocarcinoma, pancreatic adenocarcinoma and glioblastoma multiforme cell lines, even against chemotherapy-resistant lines, but with low toxicity to human hepatocytes. Therefore, the extracts of the invention are proposed for use in the treatment of colon adenocarcinoma, pancreatic adenocarcinoma and glioblastoma multiforme, including those resistant to currently used chemotherapies.
    Type: Application
    Filed: October 11, 2021
    Publication date: December 28, 2023
    Inventors: Francisco BERMÚDEZ PÉREZ, Jose Carlos PRADOS SALAZAR, Consolación MELGUIZO ALONSO, Jesús Mª PORRES FOULQUIE, Cristina MESAS HERNÁNDEZ, Rosario MARTÍNEZ MARTÍNEZ, Milagros GALISTEO MOYA, Raúl ORTIZ QUESADA, Laura CABEZA MONTILLA, María LÓPEZ-JURADO ROMERO DE LA CRUZ
  • DRUG DELIVERY SYSTEM BASED ON CALCIUM PHOSPHATE NANOPARTICLES FUNCTIONALIZED WITH BIOACTIVE COMPOUNDS FROM EUPHORBIA EXTRACT AND THE USES THEREOF
    Publication number: 20230190704
    Abstract: The present invention relates to a composition comprising the bioactive molecules esculetin and euphorbetin, which present antitumor activity, so it may be used for the treatment and/or prevention of cancer, especially for colorectal, pancreatic and glioblastoma. Furthermore, it relates to a drug delivery system composed of nanoparticles of calcium phosphate functionalized with said bioactive molecules, preferably obtained from a Euphorbia extract. The invention also refers to the obtaining of an ethanolic extract of plant origin from defatted flour of mature seed of Euphorbia.
    Type: Application
    Filed: May 5, 2021
    Publication date: June 22, 2023
    Inventors: Francisco BERMUDEZ PEREZ, José Carlos PRADOS SALAZAR, Consolacion MELGUIZO ALONSO, Jusus M PORRES FOULQUIE, Cristina MESAS HERNANDEZ, Rosario MARTINEZ MARTINEZ, Milagros GALISTEO MOYA, Raul ORTIZ QUESADA, Laura CABEZA MONTILLA, Maria LOPEZ-JURADO ROMERO DE LA C, Antonio Femando MURILLO CANCHO, Jose Manuel DELGADO LOPEZ, Victor GARCES ROBLES, Gloria Belen RAMIREZ RODRIGUEZ
  • USE OF SIGMA RECEPTOR LIGANDS IN CANCER
    Publication number: 20190142840
    Abstract: The invention relates to compounds of general formula (I) having pharmacological activity towards the sigma receptor, for use in decreasing cancer cells proliferation and improving chemotherapeutic drug efficacy.
    Type: Application
    Filed: June 5, 2017
    Publication date: May 16, 2019
    Inventors: Daniel ZAMANILLO-CASTANEDO, José-Carlos PRADOS-SALAZAR, Sebastiá VIDELA-CÉS, José-Miguel VELA-HERNÁNDEZ, Carlos-Ramón PLATA-SALAMAN, Jordi BRUNA-ESCUER
  • BIOMARKERS FOR THE DIAGNOSIS AND THE RESPONSE TO TREATMENT OF PANCREATIC CANCER
    Publication number: 20160139129
    Abstract: The invention related to biomarkers, a method and a kit for early diagnosis of pancreatic cancer, in particular of pancreatic ductal adenocarcinoma (PDAC); and to biomarkers, a method and a kit or device for predicting or prognosticating an individual's response to combination treatment with a nucleoside analogue (preferably gemcitabine) and with a growth factor receptor (preferably erlotinib) in patients with pancreatic ductal adenocarcinoma.
    Type: Application
    Filed: June 13, 2014
    Publication date: May 19, 2016
    Inventors: Carolina Torres Perales, Sonia Perales Romero, Juan Ramón Delgado Pérez, Antonio Irigoyen Medina, María José Alejandre Pérez, José Iglesias Gómez, Rogelio Palomino Morales, Octavio Caba Pérez, José Carlos Prados Salazar, Antonia Aránega Jiménez, Ana Linares Gil