Abstract: Methods and devices for detecting sites of low optical reflectivity from optical coherence tomography, OCT, of the retina are provided. The method includes segmenting retinal layers from OCT data, calculating optical reflectivity of each segmented retinal layers from the OCT data, and detecting sites of low optical reflectivity from the calculated optical reflectivity of the segmented retinal layers. The calculated optical reflectivity can be compared against a predetermined threshold obtained from a healthy population. Segmenting can be carried out according to the optical reflectivity of each identified retinal layer. OCT-Microangiography data can be displayed side-by-side or superimposed with the enface images of the calculated optical reflectivity. The device can be combined with OCT equipment, in particular for displaying the detected sites of low optical reflectivity.

Abstract: Methods and devices for detecting sites of low optical reflectivity from optical coherence tomography, OCT, of the retina are provided. The method includes segmenting retinal layers from OCT data, calculating optical reflectivity of each segmented retinal layers from the OCT data, and detecting sites of low optical reflectivity from the calculated optical reflectivity of the segmented retinal layers. The calculated optical reflectivity can be compared against a predetermined threshold obtained from a healthy population. Segmenting can be carried out according to the optical reflectivity of each identified retinal layer. OCT-Microangiography data can be displayed side-by-side or superimposed with the enface images of the calculated optical reflectivity. The device can be combined with OCT equipment, in particular for displaying the detected sites of low optical reflectivity.

Abstract: The instrument is to be adapted to an ophthalmic slit-lamp (2,6) and includes holders for fluorescence excitation and barrier filters (3,5) to the light path and a detector system made of a linear array of photodiodes (8) with respective circuitry for reading and control. The light is focused in a chosen zone of the eye (13) inducing fluorescence by using specific wavelength. The fluorescence is measured by the detector (8) coupled to one of the eyepieces (12) of the slit-lamp (26) or to a beam-splitter (7) placed before the eyepieces (12). There is a system for digitalization of the signal from the detector (8) which is connected to an IBM compatible computer (11) where the data is stored and analyzed.