Patents by Inventor José I Fernández Montequin

José I Fernández Montequin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of pharmaceutical composition containing epidermal growth factor (EGF) for diabetic foot amputation prevention
    Patent number: 7799760
    Abstract: The invention relates to the use of Epidermal Growth Factor (EGF) in a preferably-injectable pharmaceutical composition which is administered by means of infiltration into and around chronic cutaneous ischaemic lesions in order to prevent diabetic foot amputation. Said composition can be administered to recently-created surgical surfaces damaged by the effect of acute reperfusion with oxygenated blood following prolonged ischaemia, thereby preventing further surgical procedures and favoring the preservation of the extremity. The aforementioned composition can be used to improve (i) the cell microenvironment, thereby increasing the reparative and defensive capacity and viability of the is tissues and (ii) the cicatrization of cutaneous ischaemic lesions, thereby stimulating cell proliferation. The invention is suitable for use in human, veterinary and experimental medicine, specifically in vascular angiology and surgery, dermatology, burn treatment and reconstructive surgery and geriatric medicine.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: September 21, 2010
    Assignee: Centro de Ingenieria Genetica y Biotecnologia
    Inventors: Jorge Berlanga Acosta, Jose I. Fernandez Montequin, Calixto Valdes Perez, Neobalis Franco Perez, Ingrid Rojas Constantin, Hector Santana Milian, Larissa Chacon Corvea, Gerardo E. Guillen Nieto, Luis Herrera Martinez, Leonardo Canan-Haden Frias, Haydee Geronimo Perez, Jorge Sotolongo Pena
  • Use of Pharmaceutical Composition Containing Epidermal Growth Factor (EGF) for Diabetic foot Amputation Prevention
    Publication number: 20080312139
    Abstract: The invention relates to the use of Epidermal Growth Factor (EGF) in a preferably-Injectable pharmaceutical composition which is administered by means of infiltration into and around chronic cutaneous ischaemic lesions in order to prevent diabetic foot amputation. Said composition can be administered to recently-created surgical surfaces damaged by the effect of acute reperfusion with oxygenated blood following prolonged ischaemia, thereby preventing further surgical procedures and favouring the preservation of the extremity. The aforementioned composition can be used to improve (i) the cell microenvironment, thereby increasing the reparative and defensive capacity and viability of the is tissues and (ii) the cicatrisation of cutaneous ischaemic lesions, thereby stimulating cell proliferation. The invention is suitable for use in human, veterinary and experimental medicine, specifically in vascular angiology and surgery, dermatology, burn treatment and reconstructive surgery and geriatric medicine.
    Type: Application
    Filed: August 22, 2008
    Publication date: December 18, 2008
    Applicant: CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA
    Inventors: Jorge Berlanga Acosta, Jose I. Fernandez Montequin, Calixto Valdes Perez, Neobalis Franco Perez, Ingrid Rojas Constantin, Hector Santana Milian, Larissa Chacon Corvea, Gerardo E. Guillen Nieto, Luis Herrera Martinez, Leonardo Canan-Haden Frias, Haydee Geronimo Perez, Jorge Sotolongo Pena
  • Methods for enhancing healing of diabetic foot ulcers by injecting epidermal growth factor (EGF)
    Patent number: 7465704
    Abstract: The invention relates to the use of Epidermal Growth Factor (EGF) in a preferably-injectable pharmaceutical composition which is administered by means of infiltration into and around chronic cutaneous ischaemic lesions in order to prevent diabetic foot amputation. Said composition can be administered to recently-created surgical surfaces damaged by the effect of acute reperfusion with oxygenated blood following prolonged ischaemia, thereby preventing further surgical procedures and favouring the preservation of the extremity. The aforementioned composition can be used to improve (i) the cell microenvironment, thereby increasing the reparative and defensive capacity and viability of the is tissues and (ii) the cicatrisation of cutaneous ischaemic lesions, thereby stimulating cell proliferation. The invention is suitable for use in human, veterinary and experimental medicine, specifically in vascular angiology and surgery, dermatology, burn treatment and reconstructive surgery and geriatric medicine.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: December 16, 2008
    Assignee: Centro de Ingeniera Genetica y Biotecnologia
    Inventors: Jorge Berlanga Acosta, José I Fernández Montequin, Calixto Valdés Pérez, Neobalis Franco Pérez, Ingrid Rojas Constantin, Héctor Santana Milián, Larissa Chacón Corvea, Gerardo E. Guillén Nieto, Luis Herrera Martínez, Leonardo Canan-Haden Frías, Haydee Gerónimo Pérez, Jorge Sotolongo Pena