Patents by Inventor José M. C. Ribeiro
José M. C. Ribeiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10314900Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.Type: GrantFiled: January 9, 2018Date of Patent: June 11, 2019Assignees: The United States of America, as represted by the Secretary, Department of Health and Human Services, Fundaçao Oswaldo Cruz (FIOCRUZ)Inventors: Jesus G. Valenzuela, Jose M. C. Ribeiro, Aldina Barral, Manoel Barral Netto, Claudia I. Brodskyn, Regis Gomes
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Publication number: 20180147269Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.Type: ApplicationFiled: January 9, 2018Publication date: May 31, 2018Applicants: The Government of the United States of America as represented by the Secretary of the Department of, Fundaçao Oswaldo Cruz (FIOCRUZ)Inventors: Jesus G. Valenzuela, Jose M.C. Ribeiro, Aldina Barral, Manoel Barral Netto, Claudia I. Brodskyn, Regis Gomes
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Patent number: 9884100Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishishmaniasis are disclosed.Type: GrantFiled: June 7, 2016Date of Patent: February 6, 2018Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, Fundacão Oswaldo Cruz (FIOCRUZ)Inventors: Jesus G. Valenzuela, Jose M. C. Ribeiro, Aldina Barral, Manoel Barral Netto, Claudia I. Brodskyn, Regis Gomes
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Publication number: 20160279211Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishishmaniasis are disclosed.Type: ApplicationFiled: June 7, 2016Publication date: September 29, 2016Applicants: The Government of the U.S.A. as represented by the Secretary of the Department of Health and Human S, Fundaçao Oswaldo Cruz (FIOCRUZ)Inventors: Jesus G. Valenzuela, Jose M.C. Ribeiro, Aldina Barral, Manoel Barral Netto, Claudia I. Brodskyn, Regis Gomes
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Patent number: 9441022Abstract: The present invention relates to the discovery of the Aegyptin gene and Aegyptin protein, a molecule that interacts with collagen and inhibits platelet adhesion, activation and aggregation. Novel biological tools, prophylactics, therapeutics, diagnostics, and methods of use of the foregoing are also disclosed.Type: GrantFiled: September 17, 2014Date of Patent: September 13, 2016Assignees: The United States of America, as represented by the Secretary, Department of Health & Human Services, The Regents of the University of CaliforniaInventors: Eric Calvo, Osvaldo Marinotti, Jose M. C. Ribeiro, Ivo M. Francischetti
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Patent number: 9382302Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.Type: GrantFiled: July 17, 2015Date of Patent: July 5, 2016Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, Fundação Oswaldo Cruz (FIOCRUZ)Inventors: Jesus G. Valenzuela, Jose M. C. Ribeiro, Aldina Barral, Manoel Barral Netto, Claudia I. Brodskyn, Regis Gomes
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Publication number: 20150315254Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.Type: ApplicationFiled: July 17, 2015Publication date: November 5, 2015Applicants: The Government of the United States of America as represented by the Secretary of the Department of, Fundacao Oswaldo Cruz (FIOCRUZ)Inventors: Jesus G. Valenzuela, Jose M.C. Ribeiro, Aldina Barral, Manoel Barral Netto, Claudia I. Brodskyn, Regis Gomes
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Patent number: 9120867Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.Type: GrantFiled: December 5, 2013Date of Patent: September 1, 2015Assignees: The United States of America as represented by the Secretary of the Department of Health and Human ServicesInventors: Jesus G. Valenzuela, Jose M. C. Ribeiro, Aldina Barral, Manoel Netto, Claudia I. Brodskyn, Regis Gomes
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Patent number: 8980859Abstract: The present invention relates to the discovery of the Aegyptin gene and Aegyptin protein, a molecule that interacts with collagen and inhibits platelet adhesion, activation and aggregation. Novel biological tools, prophylactics, therapeutics, diagnostics, and methods of use of the foregoing are also disclosed.Type: GrantFiled: January 22, 2013Date of Patent: March 17, 2015Assignees: The United States of America, as represented by the Secretary, Department of Health & Human Services, The Regents of the University of CaliforniaInventors: Eric Calvo, Osvaldo Marinotti, Jose M. C. Ribeiro, Ivo M. Francischetti
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Publication number: 20150010589Abstract: The present invention relates to the discovery of the Aegyptin gene and Aegyptin protein, a molecule that interacts with collagen and inhibits platelet adhesion, activation and aggregation. Novel biological tools, prophylactics, therapeutics, diagnostics, and methods of use of the foregoing are also disclosed.Type: ApplicationFiled: September 17, 2014Publication date: January 8, 2015Inventors: Eric CALVO, Osvaldo MARINOTTI, Jose M.C. RIBEIRO, Ivo M. FRANCISCHETTI
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Publication number: 20140093531Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.Type: ApplicationFiled: December 5, 2013Publication date: April 3, 2014Applicants: Fundacao Oswaldo Cruz (FIOCRUZ), The Government of the United States of America as represented by the Secretary of the Department ofInventors: Jesus G. Valenzuela, Jose M.C. Ribeiro, Aldina Barral, Manoel Netto, Claudia I. Brodskyn, Regis Gomes
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Patent number: 8628780Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.Type: GrantFiled: January 7, 2009Date of Patent: January 14, 2014Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, Fundação Oswaldo Cruz (FIOCRUZ)Inventors: Jesus G. Valenzuela, Jose M. C. Ribeiro, Aldina Barral, Manoel Netto, Claudia Brodskyn, Regis Gomes
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Patent number: 8629260Abstract: The present disclosure provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present disclosure also provides compositions for vaccines to prevent Leishmaniasis.Type: GrantFiled: December 11, 2012Date of Patent: January 14, 2014Assignee: The United States of America as represented by the Secretary of the Department of Health and Human ServicesInventors: Jesus G. Valenzuela, Yasmine Belkaid, Shaden Kamhawi, David Sacks, Jose M.C. Ribeiro
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Patent number: 8383589Abstract: The present invention relates to the discovery of the Aegyptin gene and Aegyptin protein, a molecule that interacts with collagen and inhibits platelet adhesion, activation and aggregation. Novel biological tools, prophylactics, therapeutics, diagnostics, and methods of use of the foregoing are also disclosed.Type: GrantFiled: July 7, 2008Date of Patent: February 26, 2013Assignees: The United States of America, as Represented by the Secretary, Department of Health and Human Services, Regents of the University of CaliforniaInventors: Eric Calvo, Osvaldo Marinotti, Jose M. C. Ribeiro, Ivo M. Francischetti
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Patent number: 8343499Abstract: The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent Leishmaniasis.Type: GrantFiled: May 6, 2011Date of Patent: January 1, 2013Assignee: The United States of America as represented by the Secretary of the Department of Health and Human ServicesInventors: Jesus G. Valenzuela, Yasmine Belkaid, Shaden Kamhawi, David Sacks, Jose M. C. Ribeiro
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Publication number: 20110212134Abstract: The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent Leishmaniasis.Type: ApplicationFiled: May 6, 2011Publication date: September 1, 2011Inventors: Jesus G. Valenzuela, Yasmine Belkaid, Shaden Kamhawi, David Sacks, Jose M.C. Ribeiro
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Publication number: 20110189120Abstract: The present invention relates to the discovery of the Aegyptin gene and Aegyptin protein, a molecule that interacts with collagen and inhibits platelet adhesion, activation and aggregation. Novel biological tools, prophylactics, therapeutics, diagnostics, and methods of use of the foregoing are also disclosed.Type: ApplicationFiled: July 7, 2008Publication date: August 4, 2011Applicant: USA DHHS- NIHInventors: Eric Calvo, Osvaldo Marinotti, Jose M.C. Ribeiro, Ivo M. Francischetti
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Patent number: 7964576Abstract: The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent Leishmaniasis.Type: GrantFiled: April 9, 2008Date of Patent: June 21, 2011Assignee: The United States of America as represented by the Secretary of the Department of Health and Human ServicesInventors: Jesus G. Valenzuela, Yasmine Belkaid, Shaden Kamhawi, David Sacks, Jose M. C. Ribeiro
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Publication number: 20100278752Abstract: The invention generally features methods for the prevention and detection of a tick infestation. The present invention also features methods for decreasing the ability of a tick to feed on a subject.Type: ApplicationFiled: July 25, 2008Publication date: November 4, 2010Applicant: Rhode Island Board of Governors for Higher EducationInventors: Michail Kotsyfakis, Jose M.C. Ribeiro, Jesus G. Valenzuela, John F. Andersen, Jennifer M. Anderson, Shahid Karim, Thomas N. Mather
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Publication number: 20090117139Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.Type: ApplicationFiled: January 7, 2009Publication date: May 7, 2009Inventors: Jesus G. Valenzuela, Jose M.C. Ribeiro, Aldina Barral, Manoel Netto, Claudia Brodskyn, Regis Gomes