Patents by Inventor José Manuel CALDERON-MONTANO

José Manuel CALDERON-MONTANO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230329304
    Abstract: Changing the normal metabolic environment of cancer cells by using artificial diets in which the levels and ratios of specific amino acids and lipids are manipulated. Because of their DNA alterations, cancer cells will not be able to fully adapt to the new metabolic environment, which will reduce their survival capacity and their protection against the immune system. Artificial diet compositions are provided that induce remarkable anticancer activities in animal models of metastatic cancers; these activities were higher than in mice receiving the pharmacological treatments used in cancer patients. The levels of methionine and leucine have a major impact on the in vivo anticancer activity of the diets. In all the active diets, the levels of methionine are less than or equal to 0.6% and the levels of leucine are less than or equal to 10%, based on the total weight of the whole dry composition.
    Type: Application
    Filed: September 23, 2020
    Publication date: October 19, 2023
    Applicants: AMINOVITA S.L., UNIVERSIDAD DE SEVILLA
    Inventors: Miguel LÓPEZ-LÁZARO, José Manuel CALDERON-MONTANO, Julio Jose JIMENEZ-ALONSO, Emilio GUILLEN-MANCINA, Victor JIMENZ-GONZALEZ, Alfonso MATE-BARRERO, Maria Concepcion PEREZ-GUERRERO
  • Publication number: 20190092802
    Abstract: The invention relates to a compound of general formula (I), and to the use thereof in medicine, or for the production of a medicament for the treatment of different diseases, preferably a cancer such as melanoma, lung carcinoma or breast cancer. For this purpose, the invention also relates to a pharmaceutical composition comprising said compound. In addition, the invention relates to a method for producing the compound of general formula (I).
    Type: Application
    Filed: May 20, 2016
    Publication date: March 28, 2019
    Inventors: Noureddine KHIAR EL WAHABI, Inmaculada FERNANDEZ FERNANDEZ, Rocio RECIO JIMENEZ, Miguel LOPEZ LAZARO, Jose Manuel CALDERON MONTANO