Patents by Inventor José María ESTRELA ARIGÜEL

José María ESTRELA ARIGÜEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240131352
    Abstract: An apparatus (1) for treating a cancerous target site is provided. The apparatus comprises an electromagnetic emitter (10) comprising one or more electrodes with an electrically insulating coating for preventing electrical contact between the electrodes and the target site. The electromagnetic emitter (10) is configured to provide a tumour treating field at a target site (30) via the one or more electrodes, the tumour treating field being non-ionizing alternating electromagnetic field having a frequency of between 10 kHz to 300 kHz; and further having a magnetic flux density of between 0.1 pT and 1 mT. The apparatus further comprises a heat source (20) configured to provide heating at the target site to cause hyperthermia at the target site. The apparatus is configured to apply the non-ionizing alternating electromagnetic field and the heating independently. The apparatus comprises an electronic controller for electronically controlling the electromagnetic emitter and the heat source.
    Type: Application
    Filed: February 11, 2022
    Publication date: April 25, 2024
    Inventors: José María ESTRELA ARIGÜEL, José Juan HERRERA GASPAR, Rosa María CIBRIAN ORTIZ DE ANDA, Enrique NAVARRO CAMBA, María Elena OBRADOR PLA
  • Publication number: 20220160745
    Abstract: Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside, pterostilbene and a phosphodiesterase (PDE) inhibitor, including a PDE4 inhibitor such as ibudilast, and also including a thiol/cysteine donor, such as acetylcysteine.
    Type: Application
    Filed: February 25, 2020
    Publication date: May 26, 2022
    Inventors: José María ESTRELA ARIGÜEL, María Elena OBRADOR PLA, Rosario SALVADOR, Ryan W. DELLINGER
  • Patent number: 11179348
    Abstract: The present invention relates to a combination comprising pterostilbeneor pterostilbene phosphate or a pharmaceutically acceptable salt thereof, a glutathione depleting agent and a cancer chemotherapeutic agent. The invention also relates to the medical use of this combination, in particular for the treatment and/or prevention of cancer.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: November 23, 2021
    Assignees: FUNDACIÓN UNIVERSIDAD CATÓLICA DE VALENCIA SAN VICENTE MÁRTIR, UNIVERSITAT DE VALÈNCIA—ESTUDI GENERAL, FUNDACIÓ INVESTIGACIÓ HOSPITAL GENERAL UNIVERSITARI DE VALÈNCIA PER A LA INVESTIGACIÓ BIOMÈDICA I CIÈNCIES DE LA SALUT, IDCQ HOSPITALES Y SANIDAD, S.L.U.
    Inventors: José María Estrela Arigüel, María Benlloch García, María Elena Plá Obrador, Lilian Soraya Vallés Martín, María Lucía Rodríguez Romero, Joan Antoni Sirerol Talens, Javier Luis Alcácer García, José Alfredo Pellicer Artés, Rosario Salvador Palmer, Guillermo María Sáez Tormo, Concepción Cerdá Micó
  • Publication number: 20180214390
    Abstract: The present invention relates to a combination comprising pterostilbeneor pterostilbene phosphate or a pharmaceutically acceptable salt thereof, a glutathione depleting agent and a cancer chemotherapeutic agent. The invention also relates to the medical use of this combination, in particular for the treatment and/or prevention of cancer.
    Type: Application
    Filed: June 9, 2016
    Publication date: August 2, 2018
    Inventors: José María ESTRELA ARIGÜEL, María BENLLOCH GARCÍA, María Elena PLÁ OBRADOR, Lilian Soraya VALLÉS MARTÍN, María Lucía RODRÍGUEZ ROMERO, Joan Antoni SIREROL TALENS, Javier Luis ALCÁCER GARCÍA, José Alfredo PELLICER ARTÉS, Rosario SALVADOR PALMER, Guillermo María SÁEZ TORMO, Concepción CERDÁ MICÓ