Abstract: The present invention relates to testosterone topical formulations, especially high testosterone concentration formulations, such as between about 6% to about 15% w/w or higher, for the controlled release of testosterone into the systemic circulation of males and females for providing constant effective testosterone blood levels, without inducing undesired testosterone spike in blood levels or testosterone transference, following topical administration. The testosterone topical formulations of the present invention are safe, convenient to use, well tolerated, stable and easily and reproducibly manufactured on scale up. Moreover, because supra-normal and sub-normal testosterone blood levels are believed to be essentially kept to a minimum or avoided and the testosterone serum levels are believed to remain essentially constant during dose life, i.e.

Abstract: The present invention relates to pernasal testosterone bio-adhesive gel formulations for intranasal administration and testosterone replacement treatment methods for using the pernasal testosterone bio-adhesive gel formulations for providing sustained intranasal delivery of testosterone to testosterone deficient males to treat, for example, male subjects diagnosed with hypogonadism. The present invention is also concerned with a novel titration method to determine the appropriate daily treatment regimen, i.e., a BID or TID treatment regimen, to administer the intranasal gels of the present invention to treat hypogonadism or TRT.

Abstract: The invention relates to a turbine engine separate flow mixer centered on a longitudinal axis, comprising an exhaust housing, a shroud directly connected to the exhaust housing and intended to mix the flows originating in the turbine engine, said shroud comprising a metal sheet formed by a succession of first and second longitudinal strips distributed circumferentially around the longitudinal axis of the mixer by circumferentially placing the second strips on either side of the first strips, the first and second strips being configured to form the shroud when at rest and grooves in the shroud when operating, the grooves being defined by an alternation of internal lobes and of external lobes.

Abstract: The invention relates to a turbine engine separate flow mixer centered on a longitudinal axis, comprising an exhaust housing, a shroud directly connected to the exhaust housing and intended to mix the flows originating in the turbine engine, said shroud comprising a metal sheet formed by a succession of first and second longitudinal strips distributed circumferentially around the longitudinal axis of the mixer by circumferentially placing the second strips on either side of the first strips, the first and second strips being configured to form the shroud when at rest and grooves in the shroud when operating, the grooves being defined by an alternation of internal lobes and of external lobes.

Abstract: A deicer device deices both a splitter nose and inlet guide vanes of an aviation turbine engine. The device includes a splitter nose to split a stream coming from the fan into primary and secondary stream flow channels of annular shape and an inner shroud to which inlet guide vanes are fastened and including a hook that holds the inner shroud axially at its upstream end against the inner annular wall. An outer surface facing of the hook forms an angle of less than 90° with an injection orifice such that the outer surface comes progressively closer to the outer annular wall on going away from the injection orifice. The outer surface of the hook presents a minimum amount of clearance J relative to the outer annular wall such that 0.2?J/D?0.6 where D is the hydraulic diameter of an injection orifice.

Abstract: The present invention relates to lower dosage strength pernasal testosterone gel formulations for intranasal administration and treatment methods for using the lower dosage strength pernasal testosterone gel formulations for treating a female subject with anorgasmia and/or hypoactive sexual desire disorder.

Abstract: A deicer device deices both a splitter nose and inlet guide vanes of an aviation turbine engine. The device includes a splitter nose to split a stream coming from the fan into primary and secondary stream flow channels of annular shape and an inner shroud to which inlet guide vanes are fastened and including a hook that holds the inner shroud axially at its upstream end against the inner annular wall. An outer surface facing of the hook forms an angle of less than 90° with an injection orifice such that the outer surface comes progressively closer to the outer annular wall on going away from the injection orifice. The outer surface of the hook presents a minimum amount of clearance J relative to the outer annular wall such that 0.2?J/D?0.6 where D is the hydraulic diameter of an injection orifice.

Abstract: The present invention relates to lower dosage strength pernasal testosterone gel formulations for intranasal administration and treatment methods for using the lower dosage strength pernasal testosterone gel formulations for treating a female subject with anorgasmia and/or hypoactive sexual desire disorder.

Abstract: The present invention relates to lower dosage strength pernasal testosterone gel formulations for intranasal administration and treatment methods for using the lower dosage strength pernasal testosterone gel formulations for treating a female subject with anorgasmia and/or hypoactive sexual desire disorder.

Abstract: The present invention relates to lower dosage strength pernasal testosterone gel formulations for intranasal administration and treatment methods for using the lower dosage strength pernasal testosterone gel formulations for treating a female subject with anorgasmia and/or hypoactive sexual desire disorder.

Abstract: The present invention relates to lower dosage strength pernasal testosterone gel formulations for intranasal administration and treatment methods for using the lower dosage strength pernasal testosterone gel formulations for treating a female subject with anorgasmia and/or hypoactive sexual desire disorder.

Abstract: The present invention relates to testosterone topical formulations, especially high testosterone concentration formulations, such as between about 6% to about 15% w/w or higher, for the controlled release of testosterone into the systemic circulation of males and females for providing constant effective testosterone blood levels, without inducing undesired testosterone spike in blood levels or testosterone transference, following topical administration. The testosterone topical formulations of the present invention are safe, convenient to use, well tolerated, stable and easily and reproducibly manufactured on scale up. Moreover, because supra-normal and sub-normal testosterone blood levels are believed to be essentially kept to a minimum or avoided and the testosterone serum levels are believed to remain essentially constant during dose life, i.e.

Abstract: The present invention relates to testosterone topical formulations, especially high testosterone concentration formulations, such as between about 6% to about 15% w/w or higher, for the controlled release of testosterone into the systemic circulation of males and females for providing constant effective testosterone blood levels, without inducing undesired testosterone spike in blood levels or testosterone transference, following topical administration.

Abstract: The present invention relates to pernasal testosterone bio-adhesive gel formulations for intranasal administration and testosterone replacement treatment methods for using the pernasal testosterone bio-adhesive gel formulations for providing sustained intranasal delivery of testosterone to testosterone deficient males to treat, for example, male subjects diagnosed with hypogonadism. The present invention is also concerned with a novel titration method to determine the appropriate daily treatment regimen, i.e., a BID or TID treatment regimen, to administer the intranasal gels of the present invention to treat hypogonadism or TRT.

Abstract: The invention relates to a graft copolymer latex comprising the which comprises a graft copolymer ABC of at least one olefinically unsaturated monomer C and at least one modified alkyd resin A2B or modified oil A1B which modified alkyd resin A2B or modified oil A1B have chain-pendant olefinically unsaturated groups, to a process for its preparation, and the use thereof a binder in coating compositions.

Abstract: The invention relates to a graft copolymer latex comprising the which comprises a graft copolymer ABC of at least one olefinically unsaturated monomer C and at least one modified alkyd resin A2B or modified oil A1B which modified alkyd resin A2B or modified oil A1B have chain-pendant olefinically unsaturated groups, to a process for its preparation, and the use thereof a binder in coating compositions.

Abstract: In the connecting device for the electrical and mechanical connection of component conductors and for the supply or removal of the coolant to or from the hollow conductors (5) of the stator winding bars (3) of electrical machines, the hollow conductors (5) and, optionally, the solid conductors (4) of the winding bar in the winding head are held together in a metallic component (7). This component is connected to a water chamber (2) which is in turn provided with connecting fittings (6, 11) for the supply or removal of the coolant and is surrounded by an insulating jacket (10).Hitherto the production and assembly of said insulating jackets was very time-consuming. In order to shorten the assembly time, the insulating jacket comprises a preferably U-shaped insulating part (10) which is pushed over the metallic component (7), the water chamber (2) and the connecting fittings (6, 11) from the inside and overlaps the latter radially.

Abstract: The device for holding the ends of the turns of a stator winding in a dynamoelectric machine comprises an inner ring (15) and a segmented outer ring (10). The stator winding, which consists of bottom and top bars (5, 6), is supported at the end side on the said outer ring (10), which in turn is supported by brackets (8) which are fastened to the machine end face. The bottom and top bars are spaced from one another by pressure hoses (13) filled with synthetic resin. The inner ring (15) consists of two rings having a closed inner conical ring (15b), an outer, preferably multipartite conical ring (15a) and support segments (15c), it being possible for the two conical rings to be braced axially with one another. A winding overhang support constructed in such a way fulfils all practical requirements and can also be reclamped subsequently.