Abstract: The various embodiments described herein include methods, devices, and systems for customizing dental care. In one aspect, personalized toothbrush devices are 3-D printed for a plurality of users. A 3-D dental model of a respective user's mouth is obtained, and a configuration for a mouthpiece of a respective personalized toothbrush device is determined. The respective personalized toothbrush device is 3-D printed, and includes a top cleaning tray, a bottom cleaning tray, and a set of cleaning elements, each customized based at least in part on the 3-D dental model of the respective user's mouth. Each personalized toothbrush device is 3-D printed for each respective user of the plurality of users, and is different from every other user's personalized toothbrush device.