Patents by Inventor Jose A. Este

Jose A. Este has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10941121
    Abstract: The present invention refers to compounds endowed with RNA helicase DDX3 inhibitory activity of formula I and II and their therapeutic use, in particular for the treatment of viral diseases.
    Type: Grant
    Filed: January 6, 2020
    Date of Patent: March 9, 2021
    Assignee: AZIENDA OSPEDALIERA UNIVERSITARIA SENESE
    Inventors: Andreas Meyerhans, Miguel Angel Martinez De La Sierra, Annalaura Brai, Roberta Fazi, Cristina Tintori, Maurizio Botta, Jose Este-Araque, Javier Martinez
  • Publication number: 20200140398
    Abstract: The present invention refers to compounds endowed with RNA helicase DDX3 inhibitory activity of formula I and II and their therapeutic use, in particular for the treatment of viral diseases.
    Type: Application
    Filed: January 6, 2020
    Publication date: May 7, 2020
    Applicant: AZIENDA OSPEDALIERA UNIVERSITARIA SENESE
    Inventors: Andreas MEYERHANS, Miguel-Angel MARTINEZ DE LA SIERRA, Annalaura BRAI, Roberta FAZI, Cristina TINTORI, Maurizio BOTTA, Jose-Este ARAQUE, Javier MARTINEZ
  • Publication number: 20180016243
    Abstract: The present invention refers to compounds endowed with RNA helicase DDX3 inhibitory activity of formula I and II and their therapeutic use, in particular for the treatment of viral diseases.
    Type: Application
    Filed: February 12, 2016
    Publication date: January 18, 2018
    Inventors: Andreas MEYERHANS, Miguel-Angel MARTINEZ DE LA SIERRA, Annalaura BRAI, Roberta FAZI, Cristina TINTORI, Maurizio BOTTA, Jose-Este ARAQUE, Javier MARTINEZ
  • Publication number: 20100292260
    Abstract: The invention relates to 6-vinyl pyrimidine pyrimidinone derivatives and the use thereof as medicaments in particular for the treatment of HTV infections, the use thereof for preparing pharmaceutical compositions and methods for the preparation thereof.
    Type: Application
    Filed: October 13, 2006
    Publication date: November 18, 2010
    Applicant: UNIVERSITA DEGLI STUDI DE SIENA
    Inventors: Maurizio Botta, Federico Corelli, Elena Petricci, Marco Radi, Giovanni Maga, Jose A. Este, Antonello Mai
  • Publication number: 20100022769
    Abstract: The present invention describes the synthesis of the compounds of formulae (1), (2) and (3) in which m and n, which may be identical or different, may have the values 0, 2, 3, 4, 5 and 6; Z and Y, which may be identical or different, represent a nitrogenated cyclic system bonded by nitrogen or by one of the ring carbons or an NR1R2 system; and X is selected from the group consisting of hydrogen, C1-C12 alkyl, substituted alkyl, C3-C12 aryl, amino, alkylamino, nitro, hydroxy, alkoxy, halogen, carboxy or carboxamido. The use of the compounds of formulae (1), (2) and (3) as anti-HIV agents in the treatment of Acquired Immune Deficiency Syndrome (AIDS) is described.
    Type: Application
    Filed: October 26, 2007
    Publication date: January 28, 2010
    Inventors: Jordi Teixidó Closa, José Ignacio Borrell Bilbao, Santiago Nonell Marrugat, Xavier Batllori Aguilá, Sofia Pettersson Salom, Laia Ros Blancó, Maria Obdulia Rabal Gracia, Violata Pérez Nueno, José Esté Araque, Imma Clotet Codina, Mercedes Armand Ugón, Ralmon Puig De La Bellacasa