Abstract: The present invention relates to a novel class of tetrahydroisoquinoline compounds of formula I and to compositions comprising the same. The compounds and compositions of the present invention can be used as medicaments in the treatment of cancer.

Abstract: The present invention relates to a novel class of tetrahydroisoquinoline compounds of formula I and to compositions comprising the same. The compounds and compositions of the present invention can be used as medicaments in the treatment of cancer.

Abstract: The present invention relates to a novel class of tetrahydroisoquinoline compounds of formula I and to compositions comprising the same. The compounds and compositions of the present invention can be used as medicaments in the treatment of cancer.

Abstract: A tuner and rectifier circuit for wireless power transfer receivers is provided using a single inductor and two switching networks. The single inductor is used for energy exchange between the receiver resonant circuit and an output energy buffer network wherein the rectification function is met. The tuning state of the receiver resonant circuit is tracked, and the inductor is accordingly coupled with the receiver resonant circuit after an adaptive time period to inject an inductive reactance to the tank for tuning purpose.

Abstract: An electromagnetic tracking (EMT) system includes a tracked device, a tracking device, and a computing device. The EMT system is configured to receive, at the tracking device, an electromagnetic signal generated by the tracked device, determine, based on the electromagnetic signal, a set of possible positions and orientations of the tracked device relative to the tracking device, receive a measured inertial value representing a motion of the tracked device, determine an estimated inertial value corresponding to the motion of the tracked device based on at least one position and orientation of the set of possible positions and orientations, determine a difference value representing a difference between the estimated inertial value and the measured inertial value, determine a particular position and a particular orientation from the set in response to determining the difference value, and generate an output including the particular position and particular orientation.

Abstract: A tuner and rectifier circuit for wireless power transfer receivers is provided using a single inductor and two switching networks. The single inductor is used for energy exchange between the receiver resonant circuit and an output energy buffer network wherein the rectification function is met. The tuning state of the receiver resonant circuit is tracked and the inductor is accordingly coupled with the receiver resonant circuit after an adaptive time period to inject an inductive reactance to the tank for tuning purpose.

Abstract: The present invention relates to selective inhibitors of TCR, and methods of using the same.

Abstract: Power conversion device for supplying a load with a PWM signal, comprising an inductive filter having at least an output configured to be connected to the load, the device comprising: a power conversion module supplied by an input voltage and configured for providing a plurality of output signals wherein one of the plurality of output signals is supplied to the filter; a conversion ratio control stage coupled to the power conversion module; and a controller configured to: determine a requested conversion ratio based on the input voltage and a target reference voltage; and based on the requested conversion ratio, control the conversion ratio control stage to operate in either a first operating mode, whereby the power conversion module provides the output signals in accordance with a first conversion ratio, or a second operating mode, whereby the power conversion module provides the output signals in accordance with a second conversion ratio.

Abstract: The current invention relates to a driver for driving one or a plurality of LEDs (D1, D2), comprising at least one driving unit (201, 202) adapted to be supplied with a differential voltage, between one first bias voltage (VB1) and one second bias voltage (VB2), the differential voltage being adapted to be equal or larger than the largest expected variations (?VF) of the forward voltage of said one or a plurality of LEDs (D1, D2). Another aspect of the invention relates to an integrated package comprising at least an LED and associated driving unit (201, 202). Another aspect of the invention relates to a light module comprising a plurality of LEDs (D1, D2) and associated driving units (201, 202).

Abstract: A system for supplying a load comprising: an input inductor configured to receive an input voltage, a selection module connected to the inductor via a switching node, and a multi-level half-bridge stage comprising a plurality of half-bridge stages, each half-bridge stage comprising a pair of switches connected between a switching node; a power combining stage coupled to each half-bridge stage using parallel bus voltage lines output from the multi-level half-bridge stage, the power combining stage configured to output a voltage to the load; and a controller configured, based on the input voltage, to selectively control a half-bridge stage to operate in a half-bridge mode to provide a stepped-up voltage on a bus voltage line, wherein the controller is further configured to control the power combining stage to provide a voltage between the bus voltage lines and the sum of these voltages is higher than a peak of the input voltage.

Abstract: Power conversion device for supplying a load with a PWM signal, comprising an inductive filter having at least an output configured to be connected to the load, the device comprising: a power conversion module supplied by an input voltage and configured for providing a plurality of output signals wherein one of the plurality of output signals is supplied to the filter; a conversion ratio control stage coupled to the power conversion module; and a controller configured to: determine a requested conversion ratio based on the input voltage and a target reference voltage; and based on the requested conversion ratio, control the conversion ratio control stage to operate in either a first operating mode, whereby the power conversion module provides the output signals in accordance with a first conversion ratio, or a second operating mode, whereby the power conversion module provides the output signals in accordance with a second conversion ratio.

Abstract: A system for supplying a load comprising: an input inductor configured to receive an input voltage, a selection module connected to the inductor via a switching node, and a multi-level half-bridge stage comprising a plurality of half-bridge stages, each half-bridge stage comprising a pair of switches connected between a switching node; a power combining stage coupled to each half-bridge stage using parallel bus voltage lines output from the multi-level half-bridge stage, the power combining stage configured to output a voltage to the load; and a controller configured, based on the input voltage, to selectively control a half-bridge stage to operate in a half-bridge mode to provide a stepped-up voltage on a bus voltage line, wherein the controller is further configured to control the power combining stage to provide a voltage between the bus voltage lines and the sum of these voltages is higher than a peak of the input voltage.

Abstract: The current invention relates to a power conversion device (10), for supplying a load (11) with a PWM signal through an inductive output filter (105). The power conversion device (10) comprises a power conversion module (101) supplied by a DC input voltage (Vin) and is configured for providing a plurality of output signals (PWM1, . . . , PWMn) having a level amplitude that is a fraction of the input voltage (Vin) level. Each output signal is floating with a bias component equally split in a plurality of steps ranging from a determined lowest fraction level amplitude to a determined highest fraction level amplitude. The power conversion device (10) further comprises a multiplexer (103) receiving as a plurality of inputs the plurality of output signals (PWM1, . . . , PWMn). The multiplexer is configured for outputting one output signal (PWMx) selected from the plurality of inputs, whereby the output signal (PWMx) of the multiplexer (103) is connected to the output filter (105).

Abstract: The current invention relates to a LED driver (10) for driving at least two LED strings (131, 133) comprising: a dual output power converter (103) for converting an input voltage (Vin) into two different output voltages for driving two sets of said at least two LED strings (131, 133), a controller (107) for controlling the dual output power converter (103) based on at least one input set point, the dual output converter (103) comprising a switched capacitor converter comprising a plurality of switches, a plurality of capacitors, the outputs of the dual output power converter (103) being connected to internal nodes of the dual power converter (103), the controller (107) being further adapted to deliver PWM output control signals for driving the switches, the duty cycle of which being a function of said at least one input set point. The invention also relates to a lighting system (1) comprising such a driver (10).

Abstract: The current invention relates to a driver (10,20) for driving at least one main load and one auxiliary load comprising: a power converter (101) adapted to convert an input voltage (Vin) into at least one main output voltage provided through a main output (1011) for driving said main load, and at least one auxiliary output DC voltage through an auxiliary output (1013) for supplying said auxiliary load, a controller (103) adapted to control the main output based on at least one input set point, wherein the power converter (101) comprises a switched capacitor converter comprising a plurality of switches and a plurality of capacitors, the main output (1011) being connected to at least one internal node of the power converter (101), the auxiliary output (1013) being connected to a DC node of the power converter (101).

Abstract: For determining an estimate of the collision damage to a car, a body part (3) of the car is displayed in a user interface (100). Through the user interface (100), input is received from the user for drawing on the body part (3) one or more damaged areas (4c, 5c). Specifically, the damaged areas (4c, 5c) are defined in each case by an outline of the damaged areas (4c, 5c), drawn on the body part (3) by way of a drawing tool (108, 108?), or as detected from an image. Subsequently, an estimate of the repair cost (C) and the repair time (T) is generated for the user, based on the damaged area (4c, 5c) drawn on the body part (3). Enabling the user to define the outlines of damaged areas (4c, 5c) makes it possible to define and estimate efficiently, flexibly, and accurately collision damage to a car.

Abstract: The current invention relates to a driver for driving one or a plurality of LEDs (D1, D2), comprising at least one driving unit (201, 202) adapted to be supplied with a differential voltage, between one first bias voltage (VB1) and one second bias voltage (VB2), the differential voltage being adapted to be equal or larger than the largest expected variations (?VF) of the forward voltage of said one or a plurality of LEDs (D1, D2). Another aspect of the invention relates to an integrated package comprising at least an LED and associated driving unit (201, 202). Another aspect of the invention relates to a light module comprising a plurality of LEDs (D1, D2) and associated driving units (201, 202).

Abstract: The current invention relates to a LED driver (10) for driving at least two LED strings (131, 133) comprising: a dual output power converter (103) for converting an input voltage (Vin) into two different output voltages for driving two sets of said at least two LED strings (131, 133), a controller (107) for controlling the dual output power converter (103) based on at least one input set point, the dual output converter (103) comprising a switched capacitor converter comprising a plurality of switches, a plurality of capacitors, the outputs of the dual output power converter (103) being connected to internal nodes of the dual power converter (103), the controller (107) being further adapted to deliver PWM output control signals for driving the switches, the duty cycle of which being a function of said at least one input set point. The invention also relates to a lighting system (1) comprising such a driver (10).

Abstract: The current invention relates to a driver(10,20) for driving at least one main load and one auxiliary load comprising: a power converter(101) adapted to convert an input voltage(Vin) into at least one main output voltage provided through a main output(1011) for driving said main load, and at least one auxiliary output DC voltage through an auxiliary output(1013) for supplying said auxiliary load, a controller(103)adapted to control the main output based on at least one input set point, wherein the power converter(101)comprises a switched capacitor converter comprising a plurality of switches and a plurality of capacitors, the main output(1011)being connected to at least one internal node of the power converter (101), the auxiliary output(1013) being connected to a DC node of the power converter(101).

Abstract: The current invention relates to a power conversion device (10), for supplying a load (11) with a PWM signal through an inductive output filter (105). The power conversion device (10) comprises a power conversion module (101) supplied by a DC input voltage (Vin) and is configured for providing a plurality of output signals (PWM1, . . . , PWMn) having a level amplitude that is a fraction of the input voltage (Vin) level. Each output signal is floating with a bias component equally split in a plurality of steps ranging from a determined lowest fraction level amplitude to a determined highest fraction level amplitude. The power conversion device (10) further comprises a multiplexer (103) receiving as a plurality of inputs the plurality of output signals (PWM1, . . . , PWMn). The multiplexer is configured for outputting one output signal (PWMx) selected from the plurality of inputs, whereby the output signal (PWMx) of the multiplexer (103) is connected to the output filter (105).