Patents by Inventor Jose Alejandro Chabalgoity

Jose Alejandro Chabalgoity has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF PRION DISEASE
    Publication number: 20220313802
    Abstract: The present disclosure is directed to a multi-species prion protein or peptide thereof, and vaccine compositions comprising the same that are useful for the vaccination and treatment of mammalian subjects at risk of having or having prion disease. Also disclosed herein are isolated proteins and peptides, polymers, vaccines, animal bait or feed, antibodies, and methods of inhibiting the onset of or treating a prion disease.
    Type: Application
    Filed: May 11, 2020
    Publication date: October 6, 2022
    Inventors: Fernando GONI, Thomas WISNIEWSKI, Lucia YIM, Jose Alejandro CHABALGOITY, Analia ELISEI
  • Methods and pharmaceutical compositions for the treatment of bacterial infections
    Patent number: 9919029
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial infections. In particular, the present invention relates to a Toll-like receptor (TLR) agonist for use in a method for the treatment of a bacterial infection in a subject in need thereof wherein the TLR agonist is administered to the subject in combination with at least one antibiotic.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: March 20, 2018
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), Universite de Droit et de la Sante de Lille 2, Centre National de la Recherche Scientifique (CNRS), Institut Pasteur de Lille, Universite de Lille 1 Sciences et Technologies, ETH Zurich, Universidad de la Republica
    Inventors: Wolf-Dietrich Hardt, Patrick Kaiser, Jean-Claude Sirard, Christophe Carnoy, Delphine Fougeron, Jose Alejandro Chabalgoity, Natalia Munoz
  • Mucosal immunization to prevent prion infection
    Patent number: 9700607
    Abstract: Vaccines against prion disease eliciting a humoral immune response when administered mucosally are described. The vaccines comprise a prion protein, a prion protein fragment, or a non-amyloidogenic prion protein homolog and an adjuvant suitable for inducing a humoral immune response after mucosal administration. Suitable adjuvants include cholera toxin subunit B, heat-labile enterotoxin and aluminum hydroxide. Alternatively, the vaccine comprises a vector encoding a prion protein, fragment, or homolog in an attenuated Salmonella host. The vaccines can be used to prevent or treat prion disease in humans and other mammals.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: July 11, 2017
    Assignee: New York University
    Inventors: Thomas Wisniewski, Einar M. Sigurdsson, Jose Alejandro Chabalgoity, Fernando R. Goni, Blas Frangione
  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF BACTERIAL INFECTIONS
    Publication number: 20160151453
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial infections. In particular, the present invention relates to a Toll-like receptor (TLR) agonist for use in a method for the treatment of a bacterial infection in a subject in need thereof wherein the TLR agonist is administered to the subject in combination with at least one antibiotic.
    Type: Application
    Filed: July 25, 2014
    Publication date: June 2, 2016
    Inventors: Wolf-Dietrich HARDT, Patrick KAISER, Jean-Claude SIRARD, Christophe CARNOY, Delphine FOUGERON, Jose Alejandro CHABALGOITY, Natalia MUNOZ
  • MUCOSAL IMMUNIZATION TO PREVENT PRION INFECTION
    Publication number: 20150044243
    Abstract: Vaccines against prion disease eliciting a humoral immune response when administered mucosally are described. The vaccines comprise a prion protein, a prion protein fragment, or a non-amyloidogenic prion protein homolog and an adjuvant suitable for inducing a humoral immune response after mucosal administration. Suitable adjuvants include cholera toxin subunit B, heat-labile enterotoxin and aluminum hydroxide. Alternatively, the vaccine comprises a vector encoding a prion protein, fragment, or homolog in an attenuated Salmonella host. The vaccines can be used to prevent or treat prion disease in humans and other mammals.
    Type: Application
    Filed: February 6, 2014
    Publication date: February 12, 2015
    Applicant: NEW YORK UNIVERSITY
    Inventors: Thomas Wisniewski, Einar M. Sigurdsson, Jose Alejandro Chabalgoity, Fernando R. Goni, Blas Frangione
  • Mucosal immunization to prevent prion infection
    Patent number: 8685718
    Abstract: Vaccines against prion disease eliciting a humoral immune response when administered mucosally are described. The vaccines comprise a prion protein, a prion protein fragment, or a non-amyloidogenic prion protein homolog and an adjuvant suitable for inducing a humoral immune response after mucosal administration. Suitable adjuvants include cholera toxin subunit B, heat-labile enterotoxin and aluminum hydroxide. Alternatively, the vaccine comprises a vector encoding a prion protein, fragment, or homolog in an attenuated Salmonella host. The vaccines can be used to prevent or treat prion disease in humans and other mammals.
    Type: Grant
    Filed: May 20, 2004
    Date of Patent: April 1, 2014
    Assignee: New York University
    Inventors: Thomas Wisniewski, Einar M. Sigurdsson, Jose Alejandro Chabalgoity, Fernando R. Goni, Blas Frangione