Abstract: Provided are transdermal microneedle-based devices for sensing the presence and concentration of analytes such as electrolytes, biomarkers, drugs, and proteins in interstitial fluid. Also provided are methods and systems to transmit the data obtained by wired or wireless connection to a receiver and to relay the data to the user or a clinician.

Abstract: Provided are transdermal microneedle-based devices for sensing the presence and concentration of analytes such as electrolytes, biomarkers, drugs, and proteins in interstitial fluid. Also provided are methods and systems to transmit the data obtained by wired or wireless connection to a receiver and to relay the data to the user or a clinician.

Abstract: Provided are transdermal microneedle-based devices for sensing the presence and concentration of analytes such as electrolytes, biomarkers, drugs, and proteins in interstitial fluid. Also provided are methods and systems to transmit the data obtained by wired or wireless connection to a receiver and to relay the data to the user or a clinician.

Abstract: Embodiments of the invention enable sensing the presence and concentration of molecules such as electrolytes, biomarkers, chemically defined drugs and proteins in transdermal and cell interstitial body fluids. Today, these tests are generally performed by blood extraction in a clinic environment and a later analysis resulting in inconvenience to the patient, high cost, the need for specialized personnel and a delay in the results. The present invention enables performing those tests at a low cost, by non-specialized personnel or the patient him(her)self, in a home or clinic environment and provides near real time results that get communicated to the patient and authorized clinician. The invention achieves that by describing an innovative product architecture that integrating micro-needles with micro-sensors in a low cost disposable unit, a specially designed applicator for ease of use and automated wireless transmission and data analytics.