Abstract: The present invention relates to a computer-aided process for carrying out the structural design of a stiffened panel (9) made of a composite material, optimizing a target variable, comprising a first preparation phase (21) in which a Simulation Model (25) of the stiffened panel (9) with all the relevant information for the structural analysis thereof is obtained from a General Finite Element Model (23) and the modifiable variables and the restrictions (27) are defined, and a second simulation phase (51) in which the design variables are iteratively modified for the purpose of optimizing the target variable, taking into account in each iteration the load distribution changes resulting from the previous iteration, and verifying that the restrictive conditions and the safety margins associated to the pre-established failure modes are met using for that purpose simulation expert modules (55) of families of failure modes.

Abstract: The present invention relates to the use of matrix metalloproteinase MMP-10 in the preparation of a pharmaceutical composition useful for thrombolytic therapy, it also being possible for said composition to contain a plasminogen activator. Additionally, the present invention relates to said pharmaceutical composition for the treatment of thrombotic disorders.

Abstract: A continuous and batch system to produce cellulose, native lignin and unicellular protein from any form of vegetation in a closed process. The biomass is mixed in the impregnate solution of nitric acid and/or ammonium hydroxide and water. After a period of time at room temperature and atmospheric pressure the chemical solution is recycled. The biomass is moved to the reactor and heated. Evaporated impregnate is recovered via absorption tower and recycled back to chemical solution. The biomass is moved to an alkaline solution, then cooled to separate pulp from black liquor. The black liquor is pumped to a separation tank and is treated to precipitate lignin. The solution is filtered to separate sweet liquor and lignin. The lignin is dried and the sweet liquor is fermented to produce unicellular protein.

Abstract: The present invention relates to a computer-aided process for carrying out the structural design of a stiffened panel (9) made of a composite material, optimizing a target variable, comprising a first preparation phase (21) in which a Simulation Model (25) of the stiffened panel (9) with all the relevant information for the structural analysis thereof is obtained from a General Finite Element Model (23) and the modifiable variables and the restrictions (27) are defined, and a second simulation phase (51) in which the design variables are iteratively modified for the purpose of optimizing the target variable, taking into account in each iteration the load distribution changes resulting from the previous iteration, and verifying that the restrictive conditions and the safety margins associated to the pre-established failure modes are met using for that purpose simulation expert modules (55) of families of failure modes.