Abstract: It relates to a beaded nonwoven membrane comprising polymeric nanofibers and at least one active agent, wherein the active agent has a water solubility equal to or lower than 33 mg/mL. It also relates to a process for the preparation of the beaded nonwoven membrane, and to its use in medical, and veterinary applications.

Abstract: It relates to a nonwoven fabric membrane for topical use on the skin, which comprises polymeric nanofibres and an active agent in an amount from 25 to 80% by weight with respect to the total weight of the nonwoven fabric membrane, wherein the active agent is soluble in a suitable biocompatible solvent system, and wherein the membrane is capable of releasing the active agent immediately when the membrane is contacted with an appropriate amount of the suitable solvent biocompatible system in which the active agent is completely solubilised. It also relates to a process for the preparation of the nonwoven fabric membrane, to a cosmetic or sanitary product and a kit comprising them and to their therapeutic and cosmetic uses.

Abstract: The invention defines a nonwoven membrane for the controlled and sustained release of a therapeutic or cosmetic active agent in the area of the body to be treated. This nonwoven membrane comprises one single type of biocompatible electrospun nanofibers and microparticles of at least one therapeutic or cosmetic active agent which are entangled between the nanofibers, the active agent having a low water solubility.

Abstract: The invention defines a nonwoven membrane for the controlled and sustained release of a therapeutic or cosmetic active agent in the area of the body to be treated. This nonwoven membrane comprises one single type of biocompatible electrospun nanofibers and microparticles of at least one therapeutic or cosmetic active agent which are entangled between the nanofibers, the active agent having a low water solubility.

Abstract: A device for producing spun yarn by means of an airflow acting in a twisting manner on the fibers of an untwisted sliver (1) as the sliver is being conducted into and through a spindle assembly (3). The spindle assembly (3) comprises a spindle head portion (5) which conically tapers toward a spindle inlet opening (2) and is rotatable independently of a spindle core portion (7) through which the yarn is withdrawn. The device suppresses any tendency of the yarn strength to decrease at high, increasing numbers of spindle revolutions.