Patents by Inventor Jose Aramburu

Jose Aramburu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Specific inhibitors of NFAT activation by calcineurin and their use in treating immune-related diseases
    Patent number: 7816490
    Abstract: Isolated peptide fragments of the conserved regulatory domain of NFAT protein capable of inhibiting protein-protein interaction between calcineurin and NFAT, or a biologically active analog thereof are described. Isolated polynucleotides and gene therapy vectors encoding such peptide fragments are also described. In addition, methods for treating immune-related diseases or conditions and methods for high throughput screening of candidate agents are described. Pharmaceutical compositions are also provided.
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: October 19, 2010
    Assignee: Immune Disease Institute, Inc.
    Inventors: Patrick G. Hogan, Anjana Rao, Jose Aramburu
  • SPECIFIC INHIBITORS OF NFAT ACTIVATION BY CALCINEURIN AND THEIR USE IN TREATING IMMUNE-RELATED DISEASES
    Publication number: 20090186422
    Abstract: Isolated peptide fragments of the conserved regulatory domain of NFAT protein capable of inhibiting protein-protein interaction between calcineurin and NFAT, or a biologically active analog thereof are described. Isolated polynucleotides and gene therapy vectors encoding such peptide fragments are also described. In addition, methods for treating immune-related diseases or conditions and methods for high throughput screening of candidate agents are described. Pharmaceutical compositions are also provided.
    Type: Application
    Filed: October 28, 2008
    Publication date: July 23, 2009
    Inventors: Patrick G. Hogan, Anjana Rao, Jose Aramburu
  • Specific inhibitors of NFAT activation by calcineurin and their use in treating immune-related diseases
    Publication number: 20070042403
    Abstract: Isolated peptide fragments of the conserved regulatory domain of NFAT protein capable of inhibiting protein-protein interaction between calcineurin and NFAT, or a biologically active analog thereof are described. Isolated polynucleotides and gene therapy vectors encoding such peptide fragments are also described. In addition, methods for treating immune-related diseases or conditions and methods for high throughput screening of candidate agents are described. Pharmaceutical compositions are also provided.
    Type: Application
    Filed: June 23, 2006
    Publication date: February 22, 2007
    Inventors: Patrick Hogan, Anjana Rao, Jose Aramburu
  • Specific inhibitors of NFAT activation by calcineurin and their use in treating immune-related diseases
    Patent number: 7084241
    Abstract: Isolated peptide fragments of the conserved regulatory domain of NFAT protein capable of inhibiting protein—protein interaction between calcineurin and NFAT, or a biologically active analog thereof are described. Isolated polynucleotides and gene therapy vectors encoding such peptide fragments are also described. In addition, methods for treating immune-related diseases or conditions and methods for high throughput screening of candidate agents are described. Pharmaceutical compositions are also provided.
    Type: Grant
    Filed: January 31, 2002
    Date of Patent: August 1, 2006
    Assignee: The CBR Institute for Biomedical Research, Inc.
    Inventors: Patrick G. Hogan, Anjana Rao, Jose Aramburu
  • Specific inhibitors of NFAT activation by calcineurin and their use in treating immune-related diseases
    Publication number: 20040002117
    Abstract: Isolated peptide fragments of the conserved regulatory domain of NFAT protein capable of inhibiting protein-protein interaction between calcineurin and NFAT, or a biologically active analog thereof are described. Isolated polynucleotides and gene therapy vectors encoding such peptide fragments are also described. In addition, methods for treating immune-related diseases or conditions and methods for high throughput screening of candidate agents are described. Pharmaceutical compositions are also provided.
    Type: Application
    Filed: February 4, 2003
    Publication date: January 1, 2004
    Inventors: Patrick G. Hogan, Anjana Rao, Jose Aramburu, Michael H. A. Roehrl, Gerhard Wagner, Sunghyun Kang
  • Specific inhibitors of NFAT activation by calcineurin and their use in treating immune-related diseases
    Publication number: 20020132300
    Abstract: Isolated peptide fragments of the conserved regulatory domain of NFAT protein capable of inhibiting protein-protein interaction between calcineurin and NFAT, or a biologically active analog thereof are described. Isolated polynucleotides and gene therapy vectors encoding such peptide fragments are also described. In addition, methods for treating immune-related diseases or conditions and methods for high throughput screening of candidate agents are described. Pharmaceutical compositions are also provided.
    Type: Application
    Filed: January 31, 2002
    Publication date: September 19, 2002
    Applicant: Center for Blood Research
    Inventors: Patrick G. Hogan, Anjana Rao, Jose Aramburu
  • Nucleic acids encoding kp43 protein and antigenic fragments thereof
    Patent number: 5811284
    Abstract: The invention provides nucleic acids and polypeptides encoding an NK cell surface antigen from a mammal, as well as antibodies that specifically bind the NK cell surface antigen. Methods of using the nucleic acids, polypeptides, and antibodies are provided, including diagnostic kits comprising one or more of these reagents.
    Type: Grant
    Filed: May 20, 1996
    Date of Patent: September 22, 1998
    Assignees: Schering Corporation, Jose Aramburu Beltran, Miguel Lopez-Botet
    Inventors: Chiwen Chang, Jose Aramburu Beltran, Miguel Lopez-Botet, Joseph H. Phillips, Jr., Lewis L. Lanier