Patents by Inventor JOSE ARCADIO RODRIGUEZ-MARTINEZ

JOSE ARCADIO RODRIGUEZ-MARTINEZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of designing programmable inducible promoters
    Patent number: 10745693
    Abstract: Described herein is a method for identifying synthetic inducible promoters that have specified induction and/or repression for DNA binding proteins such as an allosteric transcription factor and an inducer molecule. The method includes an in vitro selection from an unselected polynucleotide library comprising a plurality of random degeneracies, and an in vivo selection to produce an induced promoter library. Produced is an induction table, which allows the selection of a promoter with specific induction and/or repression properties. Also included are biosensors containing the synthetic inducible promoters.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: August 18, 2020
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Srivatsan Raman, Aseem Zoe Ansari, Xiangyang Liu, Jose Arcadio Rodriguez-Martinez
  • METHODS OF DESIGNING PROGRAMMABLE INDUCIBLE PROMOTERS
    Publication number: 20190062730
    Abstract: Described herein is a method for identifying synthetic inducible promoters that have specified induction and/or repression for DNA binding proteins such as an allosteric transcription factor and an inducer molecule. The method includes an in vitro selection from an unselected polynucleotide library comprising a plurality of random degeneracies, and an in vivo selection to produce an induced promoter library. Produced is an induction table, which allows the selection of a promoter with specific induction and/or repression properties. Also included are biosensors containing the synthetic inducible promoters.
    Type: Application
    Filed: April 4, 2018
    Publication date: February 28, 2019
    Inventors: SRIVATSAN RAMAN, ASEEM ZOE ANSARI, XIANGYANG LIU, JOSE ARCADIO RODRIGUEZ-MARTINEZ