Patents by Inventor Jose Bontemps

Jose Bontemps has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microparticles comprising a biodegradable polymer controlling the release of an antimalaria active principle, pharmaceutical compositions comprising it and process for its preparation
    Patent number: 4897267
    Abstract: The present invention relates to microparticles containing an active principle against malaria, such as primaquine, one of its amino acid derivatives, or their conjugates with a hepatotropic vector or their pharmaceutically acceptable salts, and a biocompatible and biodegradable polymer controlling the kinetics of release of the active principle, like (DL)polylactide. The invention also relates to pharmaceutical compositions comprising microcapsules according to the invention. Lastly, the invention relates to processes for the preparation of microparticles as mentioned above, the processes comprising: dissolving the polymer in a volatile solvent, adding to this solution the active principle and possibly a substance regulating the size of the microparticles, and at the end of evaporation, recovering the microparticles by centrifugation and filtration.
    Type: Grant
    Filed: July 28, 1988
    Date of Patent: January 30, 1990
    Assignee: Ire-Celltarg S.A.
    Inventors: Jose Bontemps, Philippe Pirson, Jean-Bernard Falmagne, Robert Jerome, Philippe Teyssie, Luc Delattre, Brigitte Evrard