Abstract: A signal processing method is provided. The method includes receiving a signal input, and filtering the signal input using a nonlinear correntropy filter. The method additionally includes generating an output based upon the filtering of the signal input. The nonlinear correntropy filter can be configured as a nonlinear Wiener filter. Alternatively, the nonlinear correntropy filter can be configured as a correntropy least mean square (LMS) filter, or a correntropy Newton/LMS filter.

Abstract: A signal processing device is provided, the device having a signal input for receiving a signal conveyed over a channel and defining a received signal. The device further includes one or more filters for generating a signal response based upon the received signal. The signal response includes an estimated value of a correntropy statistic. Additionally, the device includes a decision module connected to at least one of the filters for probabilistically deciding whether the received signal contains an information signal component based upon the estimated value of the correntropy statistic. The device further includes a signal output to convey a signal output indicating the received signal corresponds to a known signal template if the decision module decides that the received signal contains the information signal component.

Abstract: The present invention relates to systems and methods for providing a short-acting analgesic agent in the management of pain during labor, wherein the system enables efficient, real-time prediction of contractions for the coordinated administration of analgesia such that the peak effectiveness of the analgesic coincides with the intermittent pain of labor.

Abstract: Systems and methods for monitoring uterus contraction activity and progress of labor. The system of the subject invention can comprises (1) a plurality of sensors; (2) an amplifying/filtering means; (3) a computing means; and (4) a graphical user interface. Accurate clinical data, which can be extracted and provided to the user in real-time using the system of the invention, include without limitation, progress of labor, prediction and monitoring of preterm labor, and intrauterine pressure prediction. In a preferred embodiment, the system of the invention includes an intelligence means, such as a neural network system, to analyze and interpret clinical data for use in clinical diagnosis as well as delivery strategy.

Abstract: A method for coding time signals based on generating an asynchronous biphasic pulse train is provided. The method includes generating response signals based upon one or more input signals. A pulse comprises a positive pulse if a voltage of the response signal is greater than a predetermined positive voltage threshold. A pulse comprises a negative pulse if the voltage of the response signal is less than a predetermined negative voltage threshold. The method further includes a method for the reconstruction of a uniformly sampled version of the original signal.

Abstract: Embodiments of the present invention described and shown in the specification and drawings include a system and method for monitoring the ventilation support provided by a ventilator and automatically supplying a breathing gas to a patient via a breathing circuit that is in fluid communication with the lungs of the patient.

Abstract: The present invention relates to systems and methods for providing a short-acting analgesic agent in the management of pain during labor, wherein the system enables efficient, real-time prediction of contractions for the coordinated administration of analgesia such that the peak effectiveness of the analgesic coincides with the intermittent pain of labor.

Abstract: A multi-scale spike detector for performing multi-resolution spike detections of a signal is provided. The spike detector includes a gamma filter having cascaded low-pass filters. The cascaded filters collectively provide different cutoff frequencies, each of the filters having a respective output. One of the filters has an input, at which the signal is received. The spike detector further includes combining circuitry that combines at least some of the respective outputs of the cascaded filters. The differences formed from this combining provide a waveform representation of the input signal. The waveform representation consists essentially of spikes that occur in the signal.

Abstract: The present invention relates to systems and methods for providing a short-acting analgesic agent in the management of pain during labor, wherein the system enables efficient, real-time prediction of contractions for the coordinated administration of analgesia such that the peak effectiveness of the analgesic coincides with the intermittent pain of labor.

Abstract: A system for monitoring medication compliance in a patient includes an electronic pill that includes a drug-transporting device and an antenna positioned on a surface of the drug-transporting device. A detector is positionable external a gastrointestinal tract of a patient for detecting a presence of the antenna in the patient gastrointestinal tract.

Abstract: A method (200) for detecting a periodic signal (141) in a noisy signal (101) is provided. The method can include applying (210) correntropy to the noisy signal to generate a non-linear mapping, and applying (220) a sub-space projection to the non-linear mapping to produce principal components. A correntropy kernel can be applied to the noisy signal to generate a Gram matrix that is used in a Temporal Principal Component Analysis (TPCA). The correntropy kernel projects nonlinearly the input data to a reproducing kernel Hilbert Space (RKHS) preserving the input time structure and attenuating impulsive noise. The correntropy kernel is data dependent, and the RKHS correlation matrix has the same dimension as the input data correlation matrix. A principal component having a majority of signal energy can be chosen (230) to detect the periodic signal.

Abstract: A set of data is stored in an input space of a kernel content addressable memory. The input space comprising the set of data is transformed into a feature space of higher dimension. The set of data is a set of transformed data within the feature space. An inner product is calculated between the set of transformed data in the feature space using a kernel function.

Abstract: A Brain Machine Interface (BMI) agent (110) is provided, that when operatively coupled to a subject during a mental task by the subject to control a prosthetic device (130), monitors one or more states (125) of neural activity of the subject, receives feedback associated with a behavior of the prosthetic device responsive to the control, learns a functional mapping between the mental task and the behavior in view of the feedback, and applies at least one control action (115) to the prosthetic device in accordance with the learning to control the prosthetic device for a targeted behavior.

Abstract: Systems and methods for monitoring uterus contraction activity and progress of labor. The system of the subject invention can comprises (1) a plurality of sensors; (2) an amplifying/filtering means; (3) a computing means; and (4) a graphical user interface. Accurate clinical data, which can be extracted and provided to the user in real-time using the system of the invention, include without limitation, progress of labor, prediction and monitoring of preterm labor, and intrauterine pressure prediction. In a preferred embodiment, the system of the invention includes an intelligence means, such as a neural network system, to analyze and interpret clinical data for use in clinical diagnosis as well as delivery strategy.

Abstract: A signal processing device is provided, the device having a signal input for receiving a signal conveyed over a channel and defining a received signal. The device further includes one or more filters for generating a signal response based upon the received signal. The signal response includes an estimated value of a correntropy statistic. Additionally, the device includes a decision module connected to at least one of the filters for probabilistically deciding whether the received signal contains an information signal component based upon the estimated value of the correntropy statistic. The device further includes a signal output to convey a signal output indicating the received signal corresponds to a known signal template if the decision module decides that the received signal contains the information signal component.

Abstract: A combined content addressable memory device and memory interface is provided. The combined device and interface includes one or more one molecular wire crossbar memories having spaced-apart key nanowires, spaced-apart value nanowires adjacent to the key nanowires, and configurable switches between the key nanowires and the value nanowires. The combination further includes a key microwire-nanowire grid (key MNG) electrically connected to the spaced-apart key nanowires, and a value microwire-nanowire grid (value MNG) electrically connected to the spaced-apart value nanowires. A key or value MNGs selects multiple nanowires for a given key or value.

Abstract: A signal processing method is provided. The method includes receiving a signal input, and filtering the signal input using a nonlinear correntropy filter. The method additionally includes generating an output based upon the filtering of the signal input. The nonlinear correntropy filter can be configured as a nonlinear Wiener filter. Alternatively, the nonlinear correntropy filter can be configured as a correntropy least mean square (LMS) filter, or a correntropy Newton/LMS filter.

Abstract: A multi-scale spike detector for performing multi-resolution spike detections of a signal is provided. The spike detector includes a gamma filter having cascaded low-pass filters. The cascaded filters collectively provide different cutoff frequencies, each of the filters having a respective output. One of the filters has an input, at which the signal is received. The spike detector further includes combining circuitry that combines at least some of the respective outputs of the cascaded filters. The differences formed from this combining provide a waveform representation of the input signal. The waveform representation consists essentially of spikes that occur in the signal.

Abstract: A method for coding time signals based on generating an asynchronous biphasic pulse train is provided. The method includes generating response signals based upon one or more input signals. A pulse comprises a positive pulse if a voltage of the response signal is greater than a predetermined positive voltage threshold. A pulse comprises a negative pulse if the voltage of the response signal is less than a predetermined negative voltage threshold. The method further includes a method for the reconstruction of a uniformly sampled version of the original signal.

Abstract: A maternal-fetal monitoring system for use during all stages of pregnancy, including antepartum and intrapartum stages. The maternal-fetal monitoring system of the subject invention comprises (1) a set of sensors; (2) an amplifying/filtering means; (3) a computing means; and (4) a graphical user interface. Accurate clinical data, which can be extracted and provided to the user in real-time using the system of the invention, include without limitation, maternal electrocardiogram (ECG) signals, maternal uterine activity signals (EHG), maternal heart rate, fetal ECG signals, and fetal heart rate. In a preferred embodiment, the maternal-fetal monitoring system of the invention includes an intelligence means, such as a neural network system, to analyze and interpret clinical data for use in clinical diagnosis antepartum, intrapartum and postpartum, as well as delivery strategy.