Abstract: Isolated stromal cells, containers comprising isolated stromal cells transfected with exogenous DNA, and methods of treating patients suffering from diseases characterized by a bone cartilage or lung defect are disclosed. The methods comprise obtaining a bone marrow sample from a donor, isolating stromal cells from the sample, and administering the isolated stromal cells to the patient.

Abstract: The present invention belongs to the field of positioning applications, particularly those requiring or benefiting from the use of geographic information and needing a high service or integrity guarantee, such as positioning by means of a satellite navigation system for users and ground vehicles circulating through a network of streets and highways for example. The invention can be used both for critical safety applications and for those entailing legal or contractual responsibilities.

Abstract: A system for determining a region searched (3003, 5001, 5002, 7002, 7003, 8001, 8002, 8003) by a moving scent detector (201) in the presence of wind, said moving scent detector having pre-calibrated scent capabilities, the system comprises: positioning means (101) attached to the moving scent detector for determining a trajectory (3001) followed by the moving scent detector; scent pattern obtainment means for obtaining an oriented scent pattern (2003, 3002, 4001); and, combination means arranged for combining said trajectory and said oriented scent pattern to obtain the region searched by said moving scent detector. The invention also relates to a method for determining a region searched by a moving scent detector in the presence of wind.

Abstract: Methods of treating patients who are suffering from a disease, disorder or condition characterized by a bone cartilage or lung defect are disclosed. The methods comprising the step of intravenous administration of stromal cells isolated from normal syngeneic individuals or intravenous administration of stromal cells isolated from the patient subsequent to correction of the genetic defect in the isolated cells. Implant devices comprising a container that has at least one membrane surface and stromal cells isolated from bone marrow that comprise a gene construct are disclosed. The gene construct in the stromal cells comprises a nucleotide sequence that encodes a beneficial protein operably linked to regulatory elements which function in stromal cells. Methods of treating individuals with diseases, disorders or conditions which can be treated with a beneficial protein, including diseases, disorders or conditions characterized by gene defects are disclosed.

Abstract: The invention relates to a method for determining a set of passable roads or areas traveled by a user with a minimum associated probability or integrity which comprises: receiving from a GNSS system respective position solutions PVT of said user in respective instants of time ta and tb, respectively, and respective position integrity ellipses, Ia and Ib (201), with respective minimum associated probabilities, Pa and Pb, that the user is located in each of them in ta and in tb, respectively, and a position increase ?ab between ta and tb with its position increase integrity ellipse Iab (204) and its associated probability Pab; obtaining from a GIS system respective passable areas corresponding to said PVT solutions, determining a first passable integral area Sa=Ia?TGIS (202) and a second passable integral area Sb=Ib?TGIS (203) as an intersection for each instant of time of said position integrity ellipses with said passable areas; propagating said first passable integral area to the subsequent instant tb by

Abstract: Methods of treating patients who are suffering from a disease, disorder or condition characterized by a bone cartilage or lung defect are disclosed. The methods comprising the step of intravenous administration of stromal cells isolated from normal syngeneic individuals or intravenous administration of stromal cells isolated from the patient subsequent to correction of the genetic defect in the isolated cells. Implant devices comprising a container that has at least one membrane surface and stromal cells isolated from bone marrow that comprise a gene construct are disclosed. The gene construct in the stromal cells comprises a nucleotide sequence that encodes a beneficial protein operably linked to regulatory elements which function in stromal cells. Methods of treating individuals with diseases, disorders or conditions which can be treated with a beneficial protein, including diseases, disorders or conditions characterized by gene defects are disclosed.

Abstract: A system for determining a region searched (3003, 5001, 5002, 7002, 7003, 8001, 8002, 8003) by a moving scent detector (201) in the presence of wind, said moving scent detector having pre-calibrated scent capabilities, the system comprises: positioning means (101) attached to the moving scent detector for determining a trajectory (3001) followed by the moving scent detector; scent pattern obtainment means for obtaining an oriented scent pattern (2003, 3002, 4001); and, combination means arranged for combining said trajectory and said oriented scent pattern to obtain the region searched by said moving scent detector. The invention also relates to a method for determining a region searched by a moving scent detector in the presence of wind.

Abstract: Methods of treating patients who are suffering from a disease, disorder or condition characterized by a bone cartilage or lung defect are disclosed. The methods comprising the step of intravenous administration of stromal cells isolated from normal syngeneic individuals or intravenous administration of stromal cells isolated from the patient subsequent to correction of the genetic defect in the isolated cells. Implant devices comprising a container that has at least one membrane surface and stromal cells isolated from bone marrow that comprise a gene construct are disclosed. The gene construct in the stromal cells comprises a nucleotide sequence that encodes a beneficial protein operably linked to regulatory elements which function in stromal cells. Methods of treating individuals with diseases, disorders or conditions which can be treated with a beneficial protein, including diseases, disorders or conditions characterized by gene defects are disclosed.

Abstract: Methods of treating patients who are suffering from a disease, disorder or condition characterized by a bone cartilage or lung defect are disclosed. The methods comprising the step of intravenous administration of stromal cells isolated from normal syngeneic individuals or intravenous administration of stromal cells isolated from the patient subsequent to correction of the genetic defect in the isolated cells. Implant devices comprising a container that has at least one membrane surface and stromal cells isolated from bone marrow that comprise a gene construct are disclosed. The gene construct in the stromal cells comprises a nucleotide sequence that encodes a beneficial protein operably linked to regulatory elements which function in stromal cells. Methods of treating individuals with diseases, disorders or conditions which can be treated with a beneficial protein, including diseases, disorders or conditions characterized by gene defects are disclosed.