Abstract: The apparatus and method of the invention provide for assigning coordinates to samples in an array. The method is based on a hierarchical pattern matching to a local lattice structure that is used as a template. Starting from the best local match, the pattern is expanded hierarchically to encompass the entire array.

Abstract: A hybrid vehicle controller operates to use GPS navigation information to determine how much energy should be delivered from or sent to, the battery. The battery charge can be better managed by using knowledge of the future path of the vehicle.

Abstract: Systems and techniques to acquire image data. In general, in one implementation, the technique includes: acquiring image data for a plurality of areas of a scan region. The technique may further include processing the image data to determine whether an area includes one or more desired features. The technique may further include designating an area as “interesting” if it includes a desired feature, and designating an area as non-interesting if it does not include the desired feature. The areas may be sub-divided one or more times, and subdivisions may be analyzed to determine if they include a desired feature.

Abstract: Systems and techniques for chromatic distortion reduction. Relative chromatic distortion information for an imaging system may be obtained, where the relative chromatic distortion information indicates relative displacement of a first color signal and a second color signal from a reference color signal in an image. The relative chromatic distortion information may be used to modify image data.

Abstract: A hybrid vehicle controller operates to use GPS navigation information to determine how much energy should be delivered from or sent to, the battery. The battery charge can be better managed by using knowledge of the future path of the vehicle.

Abstract: The present disclosure includes systems and techniques relating to intelligently directed segmentation analysis for automated microscope systems. In general, in one implementation, the technique includes obtaining an image of at least a portion of a scan region including a biological specimen, partitioning the obtained image into zelles, determining one or more parameters of the zelles, performing a cluster analysis on the one or more parameters of the zelles, differentiating tissue of greater interest from tissue of lesser interest in the obtained image based on the cluster analysis and based on a test being performed for the biological specimen, and storing more information for the tissue of greater interest than information for the tissue of lesser interest. The cluster analysis can be a multivariate statistical cluster analysis, and the zelles can be test-dependent zelles (e.g., having dimensions defined according to the test being performed for the biological specimen).

Abstract: Disclosed is a system for and a method of registering images captured by a computer-controlled microscope. The imaging system of the present invention includes a computer-controlled microscope electrically connected to a controller having a display device. The microscope further includes a barcode reader, a camera, a serial interface, one or more sensors, one or more motors, a light source, a turret, and a data interface. The method of image registration includes the steps of defining areas of interest on a microscope slide, creating a database of microscopic image locations, commanding a microscope to each location, capturing and storing an image, calculating correlation with neighbors, registering correlation scores and offsets, determining an anchor, and attaching neighbors using correlation scores and offsets.

Abstract: This disclosure provides methods and systems by which a device could detect if it has been loaded with a consumable that was not authorized by the manufacturer of the device even if the gray market could exactly remanufacture or duplicate the consumable. The methods and systems utilize an asymmetric key pair.

Abstract: Provided are methods, computer implemented methods, and devices for machine vision. The methods and devices are capable of quantifying the amount of a particular color resulting from a particular stain in a sample stained with multiple agents.

Abstract: A remote view station is communicatively coupled to an image server and receives a compressed version of source medical images. The remote view station uncompresses and displays the received medical image. A medical professional, such as a pathologist, can select a region of the displayed medical image. Region information is transmitted back to the image server that applies image analysis operations on a region of the source medical image that corresponds to the selected region of the compressed medical image. In this manner, the data loss that occurs during image compression does not effect the image analysis operations. As such, the image analysis operations produce more accurate results than if the operations were applied by remote view station to the uncompressed image.

Abstract: The apparatus and method of the invention provide for assigning coordinates to samples in an array. The method is based on a hierarchical pattern matching to a local lattice structure that is used as a template. Starting from the best local match, the pattern is expanded hierarchically to encompass the entire array.

Abstract: A block of tissue is imaged and used as a reference. Later slides formed from that tissue receive numbers, and are also imaged. The imaged slides are compared to the reference image to determine identification errors.

Abstract: A remote view station is communicatively coupled to an image server and receives a compressed version of source medical images. The remote view station uncompresses and displays the received medical image. A medical professional, such as a pathologist, can select a region of the displayed medical image. Region information is transmitted back to the image server that applies image analysis operations on a region of the source medical image that corresponds to the selected region of the compressed medical image. In this manner, the data loss that occurs during image compression does not effect the image analysis operations. As such, the image analysis operations produce more accurate results than if the operations were applied by remote view station to the uncompressed image.

Abstract: The apparatus and method of the invention provide for assigning coordinates to samples in an array. The method is based on a hierarchical pattern matching to a local lattice structure that is used as a template. Starting from the best local match, the pattern is expanded hierarchically to encompass the entire array.

Abstract: Automated projection of serial section images in microscopic imaging systems. A computer-controlled microscope that is connected electrically to a controller that has a display device. A batch of serial section slides includes a series of serial section slides, each of which has a microscope slide, a sample, and an interesting area. If one of the images is misregistered, then the images may be transformed.

Abstract: A method and apparatus for automated analysis of transmitted and fluorescently labeled biological samples, wherein the apparatus automatically scans at a low magnification to acquire images which are analyzed to determine candidate cell objects of interest. Once candidate objects of interest are identified, further analysis is conducted automatically to process and collect data from samples having different staining agents.

Abstract: A system of compensating a medical image to make it look like it came from either a different camera or from using a different dye or stain. The medical image is obtained and then processed using characteristics of the non-image related parts of the image. These non-image related parts can include the dye that was used to dye the image or the camera that was used to obtain the image. Then, the raw or partially raw image can be reprocessed using characteristics of the different non-image related part. For example, in one embodiment, the image is deconvolved to remove the influence of the camera that actually obtained the image, then reconvolved with information indicative of a different camera. In this way, the image is processed to make it look like it came from a different camera than the one that actually did in fact form it.

Abstract: Disclosed is an automated staining apparatus (autostainer) capable of staining sample on a microscope slide. The autostainer is capable of limiting the amount of reagent used through a process including image acquisition and processing techniques, wherein an image of the slide is acquired and used to determine a region on the slide to be stained. Also disclosed are methods of using images acquired by the autostainer in sample processing. In addition, a system having the autostainer functionally linked to an imaging system is provided.

Abstract: Systems, methods, and apparatus are described for the handling of biological specimens for analysis. The systems, methods and apparatus are designed to reduce errors in misidentification, incorrect processing, and recordkeeping and reporting. The systems, methods, and apparatus can also provide real time tracking of samples at any stage, from collection to processing to analyzing to storage.

Abstract: The apparatus and method of the invention provide for assigning coordinates to samples in an array. The method is based on a hierarchical pattern matching to a local lattice structure that is used as a template. Starting from the best local match, the pattern is expanded hierarchically to encompass the entire array.