Patents by Inventor Jose Eduardo Lopez

Jose Eduardo Lopez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TETRAHYDROPYRROLOTHIAZINE COMPOUNDS
    Publication number: 20140094454
    Abstract: The present invention provides compounds of Formula I: wherein A is selected from the group consisting of; R1 is H or F; R2 is H, —CH2OH, C1-C3 alkyl, R3 is H, F, or CN; R4 is H, F; or CN; and R5 is H, —CH3, or —OCH3; or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 4, 2013
    Publication date: April 3, 2014
    Applicant: Eli Lilly and Company
    Inventors: James Peter BECK, Steven James GREEN, Jose Eduardo LOPEZ, Brian Michael MATHES, Dustin James MERGOTT, Warren Jaye PORTER, Zoran RANKOVIC, Yuan SHI, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.
  • Tetrahydropyrrolothiazine compounds
    Patent number: 8629270
    Abstract: The present invention provides compounds of Formula I: wherein A is selected from the group consisting of; R1 is H or F; R2 is H, —CH2OH, C1-C3 alkyl, R3 is H, F, or CN; R4 is H, F; or CN; and R5 is H, —CH3, or —OCH3; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 27, 2013
    Date of Patent: January 14, 2014
    Assignee: Eli Lilly and Company
    Inventors: Jose Eduardo Lopez, Dustin James Mergott
  • TETRAHYDROPYRROLOTHIAZINE COMPOUNDS
    Publication number: 20130261111
    Abstract: The present invention provides compounds of Formula I: wherein A is selected from the group consisting of; R1 is H or F; R2 is H, —CH2OH, C1-C3 alkyl, R3 is H, F, or CN; R4 is H, F; or CN; and R5 is H, —CH3, or —OCH3; or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 27, 2013
    Publication date: October 3, 2013
    Applicant: Eli Lilly and Company
    Inventors: James Peter BECK, Steven James GREEN, Jose Eduardo LOPEZ, Brian Michael MATHES, Dustin James MERGOTT, Warren Jaye PORTER, Zoran RANKOVIC, Yuan SHI, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR
  • Vitamin D receptor modulators
    Patent number: 7943795
    Abstract: The present invention relates to novel, non-secosteroidal, phenyl-naphthalene compounds of Formula (I): wherein R, R1, RP, ZP, LP1, LP2 LNP, RP3, RN, and ZNP are defined herein, their preparation, pharmaceutical compositions, and methods of use.
    Type: Grant
    Filed: December 19, 2005
    Date of Patent: May 17, 2011
    Assignee: Eli Lilly and Company
    Inventors: Lynn Stacy Gossett, Jose Eduardo Lopez, Alan M. Warshawsky, Ying Kwong Yee
  • Indole sulfonamide modulators of progesterone receptors
    Patent number: 7932284
    Abstract: Compounds of Formula (I), wherein n is 1 or 2, and R1, R2, R3, R4, R5, R6, R7, and R8 are as defined herein, their preparation, pharmaceutical compositions, and methods of use are disclosed.
    Type: Grant
    Filed: January 17, 2007
    Date of Patent: April 26, 2011
    Assignee: Eli Lilly and Company
    Inventor: Jose Eduardo Lopez
  • Benzisothiazol-3-one-carboxylic acid amides as phospholipase inhibitors
    Patent number: 7595403
    Abstract: A novel class of benzisothiazole-3(2H)-one compounds is disclosed together with the use of such compounds for inhibiting hepatic lipase and/or endothelial lipase activity for treatment, amelioration or prevention of hepatic lipase and/or endothelial lipase mediated diseases.
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: September 29, 2009
    Assignee: Eli Lilly and Company
    Inventors: Patrick Irving Eacho, Patricia Sue Foxworthy-Mason, Ho-Shen Lin, Jose Eduardo Lopez, Marian Kazimierz Mosior, Michael Enrico Richett
  • VITAMIN D RECEPTOR MODULATORS
    Publication number: 20090234001
    Abstract: The present invention relates to novel, non-secosteroidal, phenyl-naphthalene compounds of Formula (I): wherein R, R1, RP, ZP, LP1, LP2 LNP, RP3, RN, and ZNP are defined herein, their preparation, pharmaceutical compositions, and methods of use.
    Type: Application
    Filed: December 19, 2005
    Publication date: September 17, 2009
    Inventors: Lynn Stacy Gossett, Jose Eduardo Lopez, Alan M. Warshawsky, Ying Kwong Yee
  • Indole Sulfonamide Modulators of Progesterone Receptors
    Publication number: 20090069400
    Abstract: Compounds of Formula (I), wherein n is 1 or 2, and R1, R2, R3, R4, R5, R6, R7, and R8 are as defined herein, their preparation, pharmaceutical compositions, and methods of use are disclosed.
    Type: Application
    Filed: January 17, 2007
    Publication date: March 12, 2009
    Inventors: Thomas John Bleisch, Christian Alexander Clarke, Jeffrey Alan Dodge, Scott Alan Jones, Jose Eduardo Lopez, Charles Willis Lugar, III, Brian Stephen Muehl, Timothy Ivo Richardson, Ying Kwong Yee, Kuo-Long Yu
  • Inhibitors of Akt (protein kinase B)
    Patent number: 7414063
    Abstract: The present invention relates to compounds Formula (I): as inhibitors of AKT activity, which are useful for the treatment of susceptible neoplasms and viral infections.
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: August 19, 2008
    Assignee: Eli Lilly and Company
    Inventors: Rima Salim Al-Awar, David Anthony Barda, Albert Gerard Dee, Kenneth James Henry, Jr., Sajan Joseph, Ho-Shen Lin, Jose Eduardo Lopez, Michael Enrico Richett, Carmen Somoza
  • Thiophene-and thiazolesulfonamides as antineoplastic agents
    Patent number: 7250430
    Abstract: The present invention provides antineoplastic compounds of the formula: and antineoplastic methods.
    Type: Grant
    Filed: June 6, 2006
    Date of Patent: July 31, 2007
    Assignee: Eli Lilly and Company
    Inventors: Cora Sue Grossman, Philip Arthur Hipskind, Ho-Shen Lin, Karen Lynn Lobb, Beatriz Lopez de Uralde Garmendia, Jose Eduardo Lopez, Mary Margaret Mader, Michael Enrico Richett, Chuan Shih, Alfonso De Dios
  • Phospholipase inhibitors
    Patent number: 7217727
    Abstract: A novel class of 3-oxo-3H-benzo[d]isoxazole carboxamide compounds is disclosed together with the use of such compounds for inhibiting hepatic lipase and/or endothelial lipase activity for treatment, amelioration or prevention of hepatic lipase and/or endothelial lipase mediated diseases.
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: May 15, 2007
    Assignee: Eli Lilly and Company
    Inventors: Patrick Irving Eacho, Patricia Sue Foxworthy-Mason, Ho-Shen Lin, Jose Eduardo Lopez, Marian Kazimierz Mosior, Michael Enrico Richett
  • Thiophene-amd thiazolesulfonamides as antineoplastic agents
    Patent number: 7084170
    Abstract: The present invention provides antineoplastic compounds of the formula: and antineoplastic methods.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: August 1, 2006
    Assignee: Eli Lilly and Company
    Inventors: Cora Sue Grossman, Philip Arthur Hipskind, Ho-Shen Lin, Karen Lynn Lobb, Beatriz Lopez de Uralde Garmendia, Jose Eduardo Lopez, Mary Margaret Mader, Michael Enrico Richett, Chuan Shih, Alfonso De Dios
  • Thiophene-amd thiazolesulfonamides as antineoplastic agents
    Publication number: 20040198784
    Abstract: The present invention provides antineoplastic compounds of the formula (D).
    Type: Application
    Filed: March 26, 2004
    Publication date: October 7, 2004
    Inventors: Cora Sue Grossman, Philip Arthur Hipskind, Ho-Shen Lin, Karen Lynn Lobb, Beatriz Lopez de Uralde Garmendia, Jose Eduardo Lopez, Mary Margaret Mader, Michael Enrico Richett, Chuan Shih, Alfonso de Dios
  • Chromogenic compound
    Patent number: 6448422
    Abstract: This application relates to a novel compound of formula I, as defined herein, processes and intermediates for its preparation and the use of the compound of formula I as a substrate for a pharmaceutical screen.
    Type: Grant
    Filed: July 3, 2000
    Date of Patent: September 10, 2002
    Assignee: Eli Lilly and Company
    Inventors: Patrick Irving Eacho, Patricia Sue Foxworthy-Mason, Richard Waltz Harper, Ho-Shen Lin, Jose Eduardo Lopez, Michael Enrico Richett