Patents by Inventor Jose Font

Jose Font has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPOSOMES AND ITS USE FOR ENZYME DELIVERY
    Publication number: 20240115502
    Abstract: The present invention refers to a liposome comprising: a) a phospholipid; b) cholesterol (chol); c) a conjugate comprising a cholesterol moiety, a polyethylene glycol (PEG) moiety and a peptide moiety comprising a RGD sequence, wherein the PEG moiety is covalently attached to the cholesterol moiety by one end via a bond of the type alkyl ether and is covalently attached to the peptide moiety comprising the RGD sequence by the other end: d) a non-lipid cationic surfactant present in a percentage of less than 30% mol in respect to the total mol of the components of the liposome a), b), c) and d); and e) alpha-galactosidase (GLA) enzyme present in a ratio of micrograms of GLA in respect to the total milligrams of the components of the liposome a), b), c) and d) of between and including 2 to 35. It also refers to a pharmaceutical composition that comprises it and to the liposome or the pharmaceutical composition for use as a medicament, in particular for use in the treatment of Fabry disease.
    Type: Application
    Filed: January 26, 2022
    Publication date: April 11, 2024
    Inventors: Leonor VENTOSA RULL, Jaume VECIANA MIRÓ, Miriam ROYO EXPOSITO, Judit TOMSEN MELERO, Ibane ABASOLO OLAORTUA, Simón SCHWARTZ NAVARRO, Jose Luis CORCHERO NIETO, Daniel PULIDO MARTINEZ, Edgar CRISTÓBAL LECINA, Elisabet GONZÁLEZ MIRA, Santiago SALA VERGÉS, Alba CÓRDOBA INSENSÉ, Josep MERLO MAS, Andreu SOLDEVILA FÁBREGA, Albert FONT INGLÉS
  • Methods for treating opioid tolerance
    Patent number: 8748480
    Abstract: The present invention relates to methods for identifying agents which bind to specific amino acid residues of the protein interaction site of G protein ? protein subunit. Compounds identified in accordance with the assay of the invention and methods for using the compound for modulating at least one activity of a G protein are also provided.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: June 10, 2014
    Assignee: University of Rochester
    Inventors: Alan V. Smrcka, Jose Font, Tabetha Bonacci
  • COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING
    Publication number: 20090221691
    Abstract: The present invention relates to methods for identifying agents which bind to specific amino acid residues of the protein interaction site of G protein ? protein subunit. Compounds identified in accordance with the assay of the invention and methods for using the compound for modulating at least one activity of a G protein are also provide.
    Type: Application
    Filed: March 7, 2006
    Publication date: September 3, 2009
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: Alan V. Smrcka, Jose Font, Tabetha Bonacci