Abstract: Compounds derived from ursodeoxycholic acid of formula (I) and to methods for obtaining same, as well as the use thereof in the treatment of polycystic diseases, particularly autosomal dominant polycystic liver disease, autosomal dominant polycystic kidney disease, or autosomal recessive polycystic kidney disease.

Abstract: The present invention relates to compounds derived from ursodeoxycholic acid of formula (I), to methods for obtaining same, as well as the use thereof in the treatment of polycystic diseases, particularly autosomal dominant polycystic liver disease, autosomal dominant polycystic kidney disease, or autosomal recessive polycystic kidney disease.

Abstract: The present invention relates to compounds derived from ursodeoxycholic acid of formula (I), to methods for obtaining same, as well as the use thereof in the treatment of polycystic diseases, particularly autosomal dominant polycystic liver disease, autosomal dominant polycystic kidney disease, or autosomal recessive polycystic kidney disease.

Abstract: The present invention comprises the use of metalloprotease inhibitors for the treatment of polycystic liver diseases (PLDs). The invention particularly describes the use of Marimastat as the preferred metalloprotease inhibitor for the treatment of PLDs. Treatment with Marimastat is able to inhibit liver cystogenesis by blocking metalloproteolytic hyperactivity of polycystic cholangiocytes.

Abstract: A video watermarking method resistant to temporal desynchronization attacks, of the type that comprises a watermark embedding, an attack stage and a watermark detection stage wherein during the watermarking embedding stage, the same watermark is hidden in a number of frames given by the mutual information between them; a temporal redundancy control is modified to hide a watermark in each possible I-frame; and during the watermark detection stage, the watermark extractor takes all the frames watermarked with the same key to extract its characteristics.

Abstract: A video watermarking method resistant to temporal desynchronization attacks, of the type that comprises a watermark embedding, an attack stage and a watermark detection stage wherein during the watermarking embedding stage, the same watermark is hidden in a number of frames given by the mutual information between them; a temporal redundancy control is modified to hide a watermark in each possible I-frame; and during the watermark detection stage, the watermark extractor takes all the frames watermarked with the same key to extract its characteristics.

Abstract: In a programming device for controlling the selective transmission of a signal to selected receivers at preselected times, commutators have their slides moved by remote control to selected commutator bars. A timing device makes connections through the commutator bars, the slide of each commutator making a connection at a different time to each different commutator bar of a given commutator. The connection made by the timing device through a commutator bar energizes a relay, which closes the circuit between the transmitter and the corresponding receiver. Parallel circuits are provided from the circuit to the transmitter to energize the transmitter only when at least one of the receivers is connected to receive. The individual commutators may each be brought to a home position also by remote control. The commutators may be mechanically driven by a motor or may be driven by stepping motors.