Patents by Inventor Jose Luis CORCHERO NIETO

Jose Luis CORCHERO NIETO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPOSOMES AND ITS USE FOR ENZYME DELIVERY
    Publication number: 20240115502
    Abstract: The present invention refers to a liposome comprising: a) a phospholipid; b) cholesterol (chol); c) a conjugate comprising a cholesterol moiety, a polyethylene glycol (PEG) moiety and a peptide moiety comprising a RGD sequence, wherein the PEG moiety is covalently attached to the cholesterol moiety by one end via a bond of the type alkyl ether and is covalently attached to the peptide moiety comprising the RGD sequence by the other end: d) a non-lipid cationic surfactant present in a percentage of less than 30% mol in respect to the total mol of the components of the liposome a), b), c) and d); and e) alpha-galactosidase (GLA) enzyme present in a ratio of micrograms of GLA in respect to the total milligrams of the components of the liposome a), b), c) and d) of between and including 2 to 35. It also refers to a pharmaceutical composition that comprises it and to the liposome or the pharmaceutical composition for use as a medicament, in particular for use in the treatment of Fabry disease.
    Type: Application
    Filed: January 26, 2022
    Publication date: April 11, 2024
    Inventors: Leonor VENTOSA RULL, Jaume VECIANA MIRÓ, Miriam ROYO EXPOSITO, Judit TOMSEN MELERO, Ibane ABASOLO OLAORTUA, Simón SCHWARTZ NAVARRO, Jose Luis CORCHERO NIETO, Daniel PULIDO MARTINEZ, Edgar CRISTÓBAL LECINA, Elisabet GONZÁLEZ MIRA, Santiago SALA VERGÉS, Alba CÓRDOBA INSENSÉ, Josep MERLO MAS, Andreu SOLDEVILA FÁBREGA, Albert FONT INGLÉS
  • Functionalized liposomes useful for the delivery of bioactive compounds
    Patent number: 9744247
    Abstract: The invention relates to conjugates in which a sterol is functionalized by an ether bond with a water-soluble polymer to which a guiding ligand is bound. These conjugates improve the physico-chemical and delivery properties of their carrying vesicles, making these more stable, homogeneous and effective. A method for their preparation, a pharmaceutical composition containing said liposomes, and their therapeutic use are described as well.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: August 29, 2017
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC), FUNDACIÓ PARC CIENTÍFIC DE BARCELONA, CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED, FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA), UNIVERSITAT DE BARCELONA, FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRON—INSTITUT DE RECERCA, UNIVERSITAT AUTÒNOMA DE BARCELONA
    Inventors: Leonor Ventosa Rull, Jaume Veciana Miró, Ingrid Cabrera Puig, Elisa Elizondo Saez De Vicuña, Marta Melgarejo Diaz, Miriam Royo Expósito, Fernando Albericio Palomera, Daniel Pulido Martinez, Santiago Sala Vergés, Jose Luis Corchero Nieto, Simón Schwartz Navarro, Ibane Abasolo Olaortua, Antonio Pedro Villaverde Corrales
  • FUNCTIONALIZED LIPOSOMES USEFUL FOR THE DELIVERY OF BIOACTIVE COMPOUNDS
    Publication number: 20150190530
    Abstract: The invention relates to conjugates in which a sterol is functionalized by an ether bond with a water-soluble polymer to which a guiding ligand is bound. These conjugates improve the physico-chemical and delivery properties of their carrying vesicles, making these more stable, homogeneous and effective. A method for their preparation, a pharmaceutical composition containing said liposomes, and their therapeutic use are described as well.
    Type: Application
    Filed: June 28, 2013
    Publication date: July 9, 2015
    Applicants: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC), FUNDACIÓ PRIVADA PARC CIENTÍFIC DE BARCELONA, CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED EN BIONG- ENIERÍA, BIOMATERIALES Y NANOMEDICINA (CIBER-BBN), FUNDACIÓ PRIVADA INSTITUT DE RECERCA BIOMÈDICA, UNIVERSITAT DE BARCELONA, FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRON- INSTITUT DE RECERCA, UNIVERSITAT AUTÒNOMA DE BARCELONA
    Inventors: Leonor Ventosa Rull, Jaume Veciana Miró, Ingrid Cabrera Puig, Elisa Elizondo Saez De Vicuña, Marta Melgarejo Diaz, Miriam Royo Expósito, Fernando Albericio Palomera, Daniel Pulido Martinez, Santiago Sala Vergés, Jose Luis Corchero Nieto, Simón Schwartz Navarro, Ibane Abasolo Olaortua, Antonio Pedro Villaverde Corrales
  • Use of Inclusion Bodies as Therapeutic Agents
    Publication number: 20140308237
    Abstract: The present invention relates to the use of inclusion bodies as vehicles for therapeutic protein delivery. This method is applicable to the delivery of therapeutic proteins to intracellular locations. In addition, the invention also relates to the administration of a cell or a pharmaceutical composition comprising inclusion bodies formed by therapeutic proteins. These inclusion bodies formed by therapeutic proteins could be used for the treatment of different diseases.
    Type: Application
    Filed: November 15, 2013
    Publication date: October 16, 2014
    Applicants: Centro de Investigacion Biomedica en Red en Bioin- genieria, Biomateriales, y Nanomedicina (Ciber BB, Universitat Autonoma de Barcelona et al.
    Inventors: Elena GARCIA-FRUITOS, Esther VAZQUEZ GOMEZ, Jose Luis CORCHERO NIETO, Antonio Pedro VILLAVERDE CORRALES