Patents by Inventor Jose Luis Navia
Jose Luis Navia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240099840Abstract: A method is provided for implanting a valve having at least one valve leaflet within the cardiovascular system of a subject. One step of the method includes preparing a substantially dehydrated bioprosthetic valve and then providing an expandable support member having oppositely disposed first and second ends and a main body portion extending between the ends. Next, the substantially dehydrated bioprosthetic valve is attached to the expandable support member so that the substantially dehydrated bioprosthetic valve is operably secured within the main body portion of the expandable support member. The expandable support member is then crimped into a compressed configuration and placed at a desired location within the cardiovascular system of the subject. Either before or after placement at the desired location, fluid, or blood re-hydrates the substantially dehydrated bioprosthetic valve.Type: ApplicationFiled: December 12, 2023Publication date: March 28, 2024Inventors: Jose Luis Navia, Ji-Feng Chen
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Publication number: 20230290541Abstract: Energy harvesting system for harvesting electric energy from a power cable including a power cable having at least one core that includes in a radial direction: an electric conductor; an insulation system surrounding the electric conductor comprising at least an insulating layer; a ground shield surrounding the insulation system; and at least one insulated metallic electrode positioned between the electric conductor and the ground shield. At least a part of an outer surface of the at least one insulated metallic electrode is not in direct contact with the ground shield. The at least one insulated metallic electrode is spaced from the electric conductor.Type: ApplicationFiled: May 21, 2021Publication date: September 14, 2023Inventors: Kleber Beloni Caliani, Ênio Roberto Da Silva Cunha, João Carlos Vieira Da Silva, João Batista Rosolem, Marcio Colazza Argentato, Claudio Floridia, Fabio Renato Bassan, João Roberto Nogueira Junior, Jose Luis Navia, Marcelo Lopes Da Silva, Artur de Araujo Silva
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Publication number: 20230277315Abstract: A method is provided for implanting a valve having at least one valve leaflet within the cardiovascular system of a subject. One step of the method includes preparing a substantially dehydrated bioprosthetic valve and then providing an expandable support member having oppositely disposed first and second ends and a main body portion extending between the ends. Next, the substantially dehydrated bioprosthetic valve is attached to the expandable support member so that the substantially dehydrated bioprosthetic valve is operably secured within the main body portion of the expandable support member. The expandable support member is then crimped into a compressed configuration and placed at a desired location within the cardiovascular system of the subject. Either before or after placement at the desired location, fluid or blood re-hydrates the substantially dehydrated bioprosthetic valve.Type: ApplicationFiled: December 9, 2022Publication date: September 7, 2023Inventors: Jose Luis Navia, Ji-Feng Chen
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Patent number: 11547560Abstract: A method is provided for implanting a valve having at least one valve leaflet within the cardiovascular system of a subject. One step of the method includes preparing a substantially dehydrated bioprosthetic valve and then providing an expandable support member having oppositely disposed first and second ends and a main body portion extending between the ends. Next, the substantially dehydrated bioprosthetic valve is attached to the expandable support member so that the substantially dehydrated bioprosthetic valve is operably secured within the main body portion of the expandable support member. The expandable support member is then crimped into a compressed configuration and placed at a desired location within the cardiovascular system of the subject. Either before or after placement at the desired location, fluid or blood re-hydrates the substantially dehydrated bioprosthetic valve.Type: GrantFiled: April 3, 2017Date of Patent: January 10, 2023Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Jose Luis Navia, Ji-Feng Chen
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Publication number: 20220110748Abstract: A method for replacing a native atrioventricular heart valve includes inserting a delivery catheter into the heart with a prosthetic apparatus retained in a compressed state inside of the delivery catheter. The prosthetic apparatus includes an annular anchoring member having a mesh structure made of Nitinol and defining a plurality of circumferentially extending rows of cells. A fabric layer is attached to an inner surface of the anchoring member. An annular support member made of Nitinol is disposed within the anchoring member. The support member is attached to the anchoring member with sutures. A prosthetic valve made of biological tissue is disposed within and secured to the support member. The method further includes allowing the prosthetic apparatus to self-expand to a radially expanded state in which the anchoring member contacts tissue of the native atrioventricular valve.Type: ApplicationFiled: December 20, 2021Publication date: April 14, 2022Applicants: The Cleveland Clinic Foundation, Edwards Lifesciences CorporationInventors: Jose Luis Navia, Ji-Feng Chen, Qun Zhou
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Publication number: 20210161657Abstract: An apparatus is provided for replacing a native cardiac valve. The native cardiac valve has at least one leaflet and is surrounded by a native cardiac valve annulus having superior and inferior aspects. The apparatus comprises a barbell-shaped, expandable anchoring member including first, second, and main body portions extending between the end portions. The main body portion includes a channel defined by inner and outer surfaces. Each of the first and second end portions has a diameter greater than the diameter of the main body portion. The first and second end portions are sized to respectively contact the superior and inferior aspects of the native cardiac valve annulus when the expandable anchoring member is in an expanded configuration. The apparatus also includes an expandable support member operably disposed within the main body portion of the expandable anchoring member, and a prosthetic cardiac valve secured within the expandable support member.Type: ApplicationFiled: October 9, 2020Publication date: June 3, 2021Inventors: Jose Luis Navia, Ji-Feng Chen, Qun Zhou
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Publication number: 20170266002Abstract: A method is provided for implanting a valve having at least one valve leaflet within the cardiovascular system of a subject. One step of the method includes preparing a substantially dehydrated bioprosthetic valve and then providing an expandable support member having oppositely disposed first and second ends and a main body portion extending between the ends. Next, the substantially dehydrated bioprosthetic valve is attached to the expandable support member so that the substantially dehydrated bioprosthetic valve is operably secured within the main body portion of the expandable support member. The expandable support member is then crimped into a compressed configuration and placed at a desired location within the cardiovascular system of the subject. Either before or after placement at the desired location, fluid or blood re-hydrates the substantially dehydrated bioprosthetic valve.Type: ApplicationFiled: April 3, 2017Publication date: September 21, 2017Inventors: Jose Luis Navia, Ji-Feng Chen
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Patent number: 9610160Abstract: A method is provided for implanting a valve having at least one valve leaflet within the cardiovascular system of a subject. One step of the method includes preparing a substantially dehydrated bioprosthetic valve and then providing an expandable support member having oppositely disposed first and second ends and a main body portion extending between the ends. Next, the substantially dehydrated bioprosthetic valve is attached to the expandable support member so that the substantially dehydrated bioprosthetic valve is operably secured within the main body portion of the expandable support member. The expandable support member is then crimped into a compressed configuration and placed at a desired location within the cardiovascular system of the subject. Either before or after placement at the desired location, fluid or blood re-hydrates the substantially dehydrated bioprosthetic valve.Type: GrantFiled: April 23, 2013Date of Patent: April 4, 2017Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Jose Luis Navia, Ji-Feng Chen
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Patent number: 9114035Abstract: An apparatus for treating cardiovascular diseases includes an expandable support member having oppositely disposed proximal and distal end portions and a main body portion between the end portions for positioning in a blood vessel. The proximal end portion of the expandable support member includes a plurality of wing members that extend from the main body portion. Each of the wing members is for engaging at least a portion of an antrum of a cardiac chamber surrounding the blood vessel. At least a portion of the expandable support member is treated with at least one therapeutic agent for eluting into the blood vessel, the cardiac chamber, and/or cardiac tissue. The expandable support member is made of wire-mesh, and at least a portion of the expandable support member may be made of a bioabsorbable material.Type: GrantFiled: April 26, 2007Date of Patent: August 25, 2015Assignee: The Cleveland Clinic FoundationInventors: Carlos Oberti, Jose Luis Navia
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Publication number: 20130238088Abstract: A method is provided for implanting a valve having at least one valve leaflet within the cardiovascular system of a subject. One step of the method includes preparing a substantially dehydrated bioprosthetic valve and then providing an expandable support member having oppositely disposed first and second ends and a main body portion extending between the ends. Next, the substantially dehydrated bioprosthetic valve is attached to the expandable support member so that the substantially dehydrated bioprosthetic valve is operably secured within the main body portion of the expandable support member. The expandable support member is then crimped into a compressed configuration and placed at a desired location within the cardiovascular system of the subject. Either before or after placement at the desired location, fluid or blood re-hydrates the substantially dehydrated bioprosthetic valve.Type: ApplicationFiled: April 23, 2013Publication date: September 12, 2013Applicant: The Cleveland ClinicInventors: Jose Luis Navia, Ji-Feng Chen
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Patent number: 8512403Abstract: An annuloplasty ring for repairing a cardiac valve includes an expandable support member having oppositely disposed proximal and distal end portions and a main body portion between the end portions. The proximal end portion of the support member includes a plurality of wing members that extend from the main body portion. Each of the wing members includes at least one hook member for embedding into a cardiac wall and the valve annulus to secure the annuloplasty ring in the valve annulus. The annuloplasty ring may be expanded into full contact engagement with the annulus of the cardiac valve by an inflatable balloon. Methods for repairing a cardiac valve using the annuloplasty ring are also provided.Type: GrantFiled: May 20, 2004Date of Patent: August 20, 2013Assignee: The Cleveland Clinic FoundationInventors: Jose Luis Navia, Jose Antonio Navia, Mark S. Goodin
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Patent number: 8480733Abstract: An apparatus for repairing a cardiac valve includes an annuloplasty ring having an expandable support member with oppositely disposed proximal and distal end portions and a main body portion between the end portions. The proximal end portion includes a plurality of wing members extending from the main body portion. Each of the wing members includes at least one hook member for embedding into a cardiac wall and a valve annulus to secure the annuloplasty ring therein. The apparatus also includes an energy delivery mechanism for selectively contracting the annuloplasty ring to restrict the valve annulus and correct valvular insufficiency. The energy delivery mechanism includes a detachable electrical lead having distal and proximal end portions. The distal end portion has a securing member for operably attaching the distal end portion to a portion of the expandable support member. The proximal end portion is operably connected to an energy delivery source.Type: GrantFiled: March 4, 2011Date of Patent: July 9, 2013Assignee: The Cleveland Clinic FoundationInventors: Jose Luis Navia, Ji-Feng Chen
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Patent number: 8216303Abstract: An apparatus is provided for treating regurgitation of blood flow through a diseased heart valve. The apparatus includes an annular support member and at least one posterior leaflet support member. The annular support member has an anterior end portion, a posterior end portion, and oppositely disposed first and second intermediate portions extending between the end portions. The at least one posterior leaflet support member is securely connected to the annular support member and is dimensioned to extend across a portion of a free edge of a posterior valve leaflet. The posterior leaflet support member comprises an arcuate center portion integrally formed with and extending between first and second end portions. The arcuate center portion has a concave shape relative to the anterior end portion. At least one of the first and second end portions is securely attached to the posterior end portion.Type: GrantFiled: November 19, 2008Date of Patent: July 10, 2012Assignee: The Cleveland Clinic FoundationInventor: Jose Luis Navia
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Publication number: 20120095551Abstract: A method is provided for implanting a valve having at least one valve leaflet within the cardiovascular system of a subject. One step of the method includes preparing a substantially dehydrated bioprosthetic valve and then providing an expandable support member having oppositely disposed first and second ends and a main body portion extending between the ends. Next, the substantially dehydrated bioprosthetic valve is attached to the expandable support member so that the substantially dehydrated bioprosthetic valve is operably secured within the main body portion of the expandable support member. The expandable support member is then crimped into a compressed configuration and placed at a desired location within the cardiovascular system of the subject. Either before or after placement at the desired location, fluid or blood re-hydrates the substantially dehydrated bioprosthetic valve.Type: ApplicationFiled: December 23, 2011Publication date: April 19, 2012Inventors: Jose Luis Navia, Ji-Feng Chen
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Patent number: 8105375Abstract: A method is provided for implanting a valve having at least one valve leaflet within the cardiovascular system of a subject. One step of the method includes preparing a substantially dehydrated bioprosthetic valve and then providing an expandable support member having oppositely disposed first and second ends and a main body portion extending between the ends. Next, the substantially dehydrated bioprosthetic valve is attached to the expandable support member so that the substantially dehydrated bioprosthetic valve is operably secured within the main body portion of the expandable support member. The expandable support member is then crimped into a compressed configuration and placed at a desired location within the cardiovascular system of the subject. Either before or after placement at the desired location, fluid or blood re-hydrates the substantially dehydrated bioprosthetic valve.Type: GrantFiled: January 17, 2008Date of Patent: January 31, 2012Assignee: The Cleveland Clinic FoundationInventors: Jose Luis Navia, Ji-Feng Chen
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Publication number: 20110153009Abstract: An apparatus for repairing a cardiac valve includes an annuloplasty ring having an expandable support member with oppositely disposed proximal and distal end portions and a main body portion between the end portions. The proximal end portion includes a plurality of wing members extending from the main body portion. Each of the wing members includes at least one hook member for embedding into a cardiac wall and a valve annulus to secure the annuloplasty ring therein. The apparatus also includes an energy delivery mechanism for selectively contracting the annuloplasty ring to restrict the valve annulus and correct valvular insufficiency. The energy delivery mechanism includes a detachable electrical lead having distal and proximal end portions. The distal end portion has a securing member for operably attaching the distal end portion to a portion of the expandable support member. The proximal end portion is operably connected to an energy delivery source.Type: ApplicationFiled: March 4, 2011Publication date: June 23, 2011Inventors: Jose Luis Navia, Ji-Feng Chen
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Patent number: 7927371Abstract: An apparatus for modifying the annulus of a cardiac valve to reduce regurgitation of blood flow through the cardiac valve includes a first annuloplasty ring having a first diameter and being disposed about a first aspect of the annulus of the cardiac valve. The apparatus also includes an elongate flexible body having proximal and distal end portions and being insertable into the first annuloplasty ring. The elongate flexible body has an adjustable mechanism for selectively adjusting the elongate flexible body from a first relaxed configuration to a second tensioned configuration. The first annuloplasty ring is adaptable to obtain a second smaller diameter and to cause the annulus of the cardiac valve to be modified and reduce regurgitation of blood flow through the cardiac valve when the elongate flexible body obtains the second tensioned configuration.Type: GrantFiled: October 26, 2006Date of Patent: April 19, 2011Assignee: The Cleveland Clinic FoundationInventors: Jose Luis Navia, Jose Antonio Navia, Ghassan Kassab
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Patent number: 7914576Abstract: An apparatus for repairing a cardiac valve includes an annuloplasty ring having an expandable support member with oppositely disposed proximal and distal end portions and a main body portion between the end portions. The proximal end portion includes a plurality of wing members extending from the main body portion. Each of the wing members includes at least one hook member for embedding into a cardiac wall and a valve annulus to secure the annuloplasty ring therein. The apparatus also includes an energy delivery mechanism for selectively contracting the annuloplasty ring to restrict the valve annulus and correct valvular insufficiency. The energy delivery mechanism includes a detachable electrical lead having distal and proximal end portions. The distal end portion has a securing member for operably attaching the distal end portion to a portion of the expandable support member. The proximal end portion is operably connected to an energy delivery source.Type: GrantFiled: May 4, 2007Date of Patent: March 29, 2011Assignee: The Cleveland Clinic FoundationInventors: Jose Luis Navia, Ji-Feng Chen
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Publication number: 20100312333Abstract: An apparatus is provided for replacing a native cardiac valve. The native cardiac valve has at least one leaflet and is surrounded by a native cardiac valve annulus having superior and inferior aspects. The apparatus comprises a barbell-shaped, expandable anchoring member including first, second, and main body portions extending between the end portions. The main body portion includes a channel defined by inner and outer surfaces. Each of the first and second end portions has a diameter greater than the diameter of the main body portion. The first and second end portions are sized to respectively contact the superior and inferior aspects of the native cardiac valve annulus when the expandable anchoring member is in an expanded configuration. The apparatus also includes an expandable support member operably disposed within the main body portion of the expandable anchoring member, and a prosthetic cardiac valve secured within the expandable support member.Type: ApplicationFiled: April 28, 2010Publication date: December 9, 2010Inventors: Jose Luis Navia, Ji-Feng Chen, Qun Zhou
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Publication number: 20100036401Abstract: A vascular graft includes an elongated main body portion having a distal end portion defining a first opening and a second proximal end portion defining a second opening. The vascular graft also includes a first sewing ring having a base portion securely attached to the first distal end portion of the elongated body portion, and a second sewing ring having a base portion securely attached to the first distal end portion at a location proximal to the first sewing ring. The first and second base portions form a channel for receiving an end portion of a blood vessel.Type: ApplicationFiled: July 7, 2009Publication date: February 11, 2010Inventor: JOSE LUIS NAVIA