Patents by Inventor Jose M. C. Berlanga

Jose M. C. Berlanga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bis-naphthalimides for the treatment of cancer
    Patent number: 5616589
    Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula1. A compound of the Formula ##STR1## wherein X, X', X" and X'", A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
    Type: Grant
    Filed: August 9, 1994
    Date of Patent: April 1, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerhard Keilhauer, Cynthia Romerdahl, Miguel F. Bra na, Xiao-Dong Qian, Peter Bousquet, Jose M.C. Berlanga, Marina M. Moset, Maria J.P. de Vega
  • Amonafide salts
    Patent number: 5420137
    Abstract: The monohydrochloride and the monomethanesulfonate of amonafide are described. The salts have good pharmaceutical properties besides their antitumor action.
    Type: Grant
    Filed: June 20, 1994
    Date of Patent: May 30, 1995
    Assignee: Knoll AG
    Inventors: Miguel F. Brana, Jose M. C. Berlanga, Reinhard Spengler, Christine Tetzner
  • Method for treating leukemias using N-(2-dimethylaminoethyl)-3-amino-1,8-naphthalimide for treating leukemias and solid tumors
    Patent number: 5183821
    Abstract: N-(2-dimethylaminoethyl)-3-amino-1,8-naphthalimide (amonafide) is an effective agent for the treatment of leukemias and solid tumors.
    Type: Grant
    Filed: July 8, 1991
    Date of Patent: February 2, 1993
    Assignee: Laboratories Knoll, S.A.
    Inventors: Miguel F. Brana, Antonio M. Sanz, Rafael P. Alvarez-Ossorio, Cristobal M. Roldan, Cristina R. F. De Gamboa, Jesus G. Garcia, Jose M. C. Berlanga
  • Bisnaphthalimides
    Patent number: 4874863
    Abstract: Bisnaphthalimides of the formula I ##STR1## where X.sup.1 to X.sup.4 and R have the meanings stated in the description, and their preparation are described. The compounds are cytotoxic towards human cells in vitro.
    Type: Grant
    Filed: March 1, 1988
    Date of Patent: October 17, 1989
    Assignee: Knoll AG
    Inventors: Miguel F. Brana, Jose M. C. Berlanga, Gerhard Keilhauer, Erich Schlick
  • N-Aminoethyl-substituted-3-nitronaphthalimides
    Patent number: 4146720
    Abstract: Compounds having the formula ##STR1## wherein Y is 2-dimethylaminoethyl, 2-diethylaminoethyl, 2-(N-pyrrolidino)ethyl or 2-(N-piperidino)ethyl. The compounds are prepared by reacting 3-nitronaphthalic acid, or corresponding anhydride, with the corresponding primary amine. The compounds possess cytostatic and raticide properties.
    Type: Grant
    Filed: September 19, 1977
    Date of Patent: March 27, 1979
    Assignee: Laboratorios Made, S.A.
    Inventors: Cristobal M. Roldan, Miguel F. Brana, Jose M. C. Berlanga