Patents by Inventor Jose M. Vega

Jose M. Vega has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dihydroxy open-acid and salts of HMG-Co-A reductase inhibitors
    Publication number: 20030211151
    Abstract: The instant invention provides methods and pharmaceutical compositions for inhibiting HMG-CoA reductase, as well as for treating and/or reducing the risk for diseases and conditions affected by inhibition of HMG-CoA reductase, comprising orally administering a therapeutically effective amount of a compound selected from a dihydroxy open acid statin and a pharmaceutically acceptable salt or ester thereof in a delayed-release pharmaceutical dosage form to a patient in need of such treatment wherein substantial release of the compound from the dosage form is delayed until after passage of the dosage form through the stomach.
    Type: Application
    Filed: April 29, 2003
    Publication date: November 13, 2003
    Applicant: Merck & Co., Inc.
    Inventors: Richard D. Tillyer, Paul J. Reider, Edward J. J. Grabowski, Feng Xu, Jose M. Vega, Mandana Asgharnejad
  • Dihydroxy open-acid salt of simvastatin
    Publication number: 20030176501
    Abstract: The instant invention provides methods and pharmaceutical compositions for inhibiting HMG-CoA reductase, as well as for treating and/or reducing the risk for diseases and conditions affected by inhibition of HMG-CoA reductase, comprising orally administering a therapeutically effective amount of a crystalline hydrated form of the calcium salt of dihydroxy open acid simvastatin to a patient in need of such treatment. Methods for making the calcium salt of dihydroxy open acid simvastatin are also provided.
    Type: Application
    Filed: November 13, 2002
    Publication date: September 18, 2003
    Inventors: Richard D. Tillyer, Paul J. Reider, Edward J. J. Grabowski, Feng Xu, Robert M. Wenslow, Jose M. Vega, Richard J. Varsolona
  • Dihydroxy open-acid and salts of HMG-CoA reductase inhibitors
    Patent number: 6569461
    Abstract: The instant invention provides methods and pharmaceutical compositions for inhibiting HMG-CoA reductase, as well as for treating and/or reducing the risk for diseases and conditions affected by inhibition of HMG-CoA reductase, comprising orally administering a therapeutically effective amount of a compound selected from a dihydroxy open acid statin and a pharmaceutically acceptable salt or ester thereof in a delayed-release pharmaceutical dosage form to a patient in need of such treatment wherein substantial release of the compound from the dosage form is delayed until after passage of the dosage form through the stomach.
    Type: Grant
    Filed: April 26, 2000
    Date of Patent: May 27, 2003
    Assignee: Merck & Co., Inc.
    Inventors: Richard D. Tillyer, Paul J. Reider, Edward J. J. Grabowski, Feng Xu, Jose M. Vega, Mandana Asgharnejad