Patents by Inventor Jose Manuel FERNANDEZ-REAL

Jose Manuel FERNANDEZ-REAL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for diagnosing hepatic fibrosis
    Patent number: 10337069
    Abstract: The present invention concerns methods, in particular in vitro methods, for diagnosing liver fibrosis in a subject suffering from obesity, or for selecting a subject suffering from obesity for liver biopsy or for treatment. The present invention also pertains to methods for screening a probiotic, a prebiotic, a chemical compound or a biological compound suitable for preventing and/or treating liver fibrosis.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: July 2, 2019
    Assignees: VAIOMER, UNIVERSITÀ DEGLI STUDI DI ROMA TOR VERGATA, FUNDACIÓ INSTITUT D'INVESTIGACIÓ BIOMÈDICA DE GIRONA DR. JOSEP TRUETA
    Inventors: Michael Courtney, Benjamin Lelouvier, Massimo Federici, Jose Manuel Fernandez-Real, Sandrine Païssé
  • METHOD FOR DIAGNOSING HEPATIC FIBROSIS BASED ON BACTERIAL PROFILE AND DIVERSITY
    Publication number: 20190062810
    Abstract: The present invention concerns methods for diagnosing liver fibrosis in an obese subject, said method comprising the steps of a) determining bacterial diversity in a biological sample from the subject, and b) based on the result of the bacterial diversity determination in step a), diagnosing liver fibrosis in the subject, or comprising the steps of a1) determining the proportion of bacteria belonging to a particular taxon and the proportion of bacteria belonging to at least one other particular taxon, in a biological sample of said subject, a2) combining the proportions determined in step a1) to obtain a combination value, and b) based on the combination value obtained in step a2), diagnosing liver fibrosis in the subject.
    Type: Application
    Filed: September 9, 2016
    Publication date: February 28, 2019
    Inventors: Benjamin LELOUVIER, Florence SERVANT, Michael COURTNEY, Massimo FEDERICI, Jose Manuel FERNANDEZ-REAL
  • METHOD FOR DIAGNOSING HEPATIC FIBROSIS
    Publication number: 20170044612
    Abstract: The present invention concerns methods, in particular in vitro methods, for diagnosing liver fibrosis in a subject suffering from obesity, or for selecting a subject suffering from obesity for liver biopsy or for treatment. The present invention also pertains to methods for screening a probiotic, a prebiotic, a chemical compound or a biological compound suitable for preventing and/or treating liver fibrosis.
    Type: Application
    Filed: April 23, 2015
    Publication date: February 16, 2017
    Inventors: Michael COURTNEY, Benjamin LELOUVIER, Massimo FEDERICI, Jose Manuel FERNANDEZ-REAL, Sandrine PAÏSSÉ
  • Method for detecting a predisposition to develop gestational diabetes mellitus and treatment for this disease
    Publication number: 20090247454
    Abstract: Methods and kits for detecting a predisposition to develop gestational diabetes mellitus and pharmacological treatment for this disease.
    Type: Application
    Filed: September 27, 2005
    Publication date: October 1, 2009
    Applicant: MELLITUS, S.L.
    Inventors: Jose Manuel Fernandez-Real Lemos, Wifredo Ricart Engel
  • Use of BPI Protein for Treatment of Diseases
    Publication number: 20090215684
    Abstract: Use of a bactericidal/permeability-increasing (BPI) protein product for the manufacture of a medicament for therapeutic or preventive treatment of a disease involving a clinical disorder associated with insulin resistance in a human.
    Type: Application
    Filed: July 7, 2006
    Publication date: August 27, 2009
    Applicant: BRIDGE BIORESEARCH LIMITED
    Inventors: Jose Manuel Fernandez-Real Lemos, Wifredo Ricart Engel