Patents by Inventor Jose Maria Castellano Berlanga

Jose Maria Castellano Berlanga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-pyrazolin-5-ones
    Patent number: 7060822
    Abstract: Chemical compounds having structural formula I and physiologically acceptable salts thereof, are inhibitors of serine/threonine and tyrosine kinase activity. Several of the tyrosine kinases, whose activity is inhibited by these chemical compounds, are involved in angiogenic processes. Thus, these chemical compounds can ameliorate disease states where angiogenesis or endothelial cell hyperproliferation is a factor. These compounds can be used to treat cancer and hyperproliferative disorders.
    Type: Grant
    Filed: July 24, 2000
    Date of Patent: June 13, 2006
    Assignee: Abbott GmbH & Co. KG
    Inventors: Lee Arnold, Marina Moran Moset, Jose Maria Castellano Berlanga, Isabel Fernandez, David J. Calderwood, Paul Rafferty
  • Bis-naphthalimides for the treatment of cancer
    Patent number: 5981753
    Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula1. A compound of the Formula ##STR1## wherein X, X', X" and X'", A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
    Type: Grant
    Filed: July 15, 1997
    Date of Patent: November 9, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerhard Keilhauer, Cynthia Romerdahl, Miguel Fernandez Brana, Xiao-Dong Qian, Peter Bousquet, Jose Maria Castellano Berlanga, Marina Moran Moset, Maria Jesus Perez De Vega
  • Bis-naphthalimides for the treatment of cancer
    Patent number: 5789418
    Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula1. A compound of the Formula ##STR1## wherein X, X', X" and X'", A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
    Type: Grant
    Filed: February 18, 1997
    Date of Patent: August 4, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerhard Keilhauer, Cynthia Romerdahl, Miguel Fernandez Brana, Xiao-Dong Qian, Peter Bousquet, Jose Maria Castellano Berlanga, Marina Moran Moset, Maria Jesus Perez De Vega
  • Dihydrodibenzisoquinolinediones
    Patent number: 5703089
    Abstract: Novel bis-1,2-dihydro-3H-dibenzisoquinoline-1,3-diones and their salts, processes for their preparation, pharmaceutical compositions containing them and methods of using them to treat malignancies, mainly human solid tumor carcinomas.
    Type: Grant
    Filed: August 19, 1996
    Date of Patent: December 30, 1997
    Assignee: Knoll Aktiengesellschaft
    Inventors: Miguel Fernandez Brana, Jose Maria Castellano Berlanga, Cynthia Romerdahl
  • Compounds 5-hydroxytryptophan glutamate and its derivatives
    Patent number: 4029807
    Abstract: The invention relates to the compound 5-Hydroxytryptophan Glutamate, having anti-depressive action.
    Type: Grant
    Filed: April 8, 1975
    Date of Patent: June 14, 1977
    Assignee: Laboratorios Made, S.A.
    Inventors: Cristobal Martinez Roldan, Miguel Fernandez Brana, Jose Maria Castellano Berlanga
  • Mepyramine theophylline acetate
    Patent number: 3962243
    Abstract: The 7-theophylline acetic acid salt of mepyramine possesses bronchial spasmolytic, antiarrhythmic, cerebral oxidation inhibitor and platelet aggregation inhibitor properties. It is prepared by slowly adding a solution of mepyramine to a suspension of 7-theophylline acetic acid in the same solvent to effect the salt-forming reaction. It can be incorporated in various pharmaceutical unit dosage forms.
    Type: Grant
    Filed: October 16, 1974
    Date of Patent: June 8, 1976
    Assignee: Laboratories Made, S.A.
    Inventors: Cristobal Martinez Roldan, Miguel Fernandez Brana, Jose Maria Castellano Berlanga
  • Method for industrial production of N-substituted dipropylacetamides
    Patent number: 3951995
    Abstract: Compounds having the formula ##EQU1## wherein R is 2-picolyl, 3-picolyl or 4-picolyl. The compounds are prepared by reacting dipropylacetic acid, or the corresponding chloride or anhydride, with 2-picolylamine, 3-picolylamine or 4-picolylamine. The compounds possess anti-convulsant and barbiturate potentiation properties.
    Type: Grant
    Filed: October 24, 1974
    Date of Patent: April 20, 1976
    Assignee: Laboratorios Made, S.A.
    Inventors: Christobal Martinez Roldan, Miguel Fernandez Brana, Jose Maria Castellano Berlanga