Patents by Inventor Jose Martin SOSA
Jose Martin SOSA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11904322Abstract: The present disclosure provides methods and processes for increasing the efficiency and accuracy of nucleic acid sequencing using techniques such as polymerase chain reaction (PCR). Methods and systems provided herein may facilitate performing reactions such as emulsion PCR (ePCR) on samples comprising nucleic acids and beads. The methods provided herein may provide a higher throughput compared to existing technologies.Type: GrantFiled: February 16, 2022Date of Patent: February 20, 2024Assignee: ULTIMA GENOMICS, INC.Inventors: Jose Martin Sosa, Joseph Anthony, Nathan Beckett, Gilad Almogy, Chandan Shee, Phillip You Fai Lee, Yuto Watanabe
-
Publication number: 20220168745Abstract: The present disclosure provides methods and processes for increasing the efficiency and accuracy of nucleic acid sequencing using techniques such as polymerase chain reaction (PCR). Methods and systems provided herein may facilitate performing reactions such as emulsion PCR (ePCR) on samples comprising nucleic acids and beads. The methods provided herein may provide a higher throughput compared to existing technologies.Type: ApplicationFiled: February 16, 2022Publication date: June 2, 2022Inventors: Jose Martin SOSA, Joseph ANTHONY, Nathan BECKETT, Gilad ALMOGY, Chandan SHEE, Phillip You Fai LEE, Yuto WATANABE
-
Publication number: 20220162696Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.Type: ApplicationFiled: December 6, 2021Publication date: May 26, 2022Inventors: Nathan BECKETT, Gilad ALMOGY, Nathan CASWELL, Jacob A. WOLF, Kristopher BARBEE, Denis PRISTINSKI, Mark PRATT, Gene POLOVY, Osip SCHWARTZ, Stephanie KUBECKA, Steven MENCHEN, Joseph ANTHONY, Jose Martin SOSA, Phillip You Fai LEE
-
Patent number: 11268143Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.Type: GrantFiled: May 5, 2021Date of Patent: March 8, 2022Assignee: Ultima Genomics, Inc.Inventors: Nathan Beckett, Gilad Almogy, Nathan Caswell, Jacob A. Wolf, Kristopher Barbee, Denis Pristinski, Mark Pratt, Gene Polovy, Osip Schwartz, Stephanie Kubecka, Steven Menchen, Joseph Anthony, Jose Martin Sosa, Phillip You Fai Lee
-
Publication number: 20220064727Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.Type: ApplicationFiled: September 14, 2021Publication date: March 3, 2022Inventors: Gilad Almogy, Nathan Beckett, Jacob A. Wolf, Nathan Caswell, Joseph Anthony, Jose Martin Sosa, Phillip Lee, Stephanie Kubecka
-
Patent number: 11155868Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.Type: GrantFiled: January 22, 2021Date of Patent: October 26, 2021Assignee: ULTIMA GENOMICS, INC.Inventors: Gilad Almogy, Nathan Beckett, Jacob A. Wolf, Nathan Caswell, Joseph Anthony, Jose Martin Sosa, Phillip Lee, Stephanie Kubecka
-
Publication number: 20210277464Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.Type: ApplicationFiled: May 5, 2021Publication date: September 9, 2021Inventors: Nathan BECKETT, Gilad ALMOGY, Nathan CASWELL, Jacob A. WOLF, Kristopher BARBEE, Denis PRISTINSKI, Mark PRATT, Gene POLOVY, Osip SCHWARTZ, Stephanie KUBECKA, Steven MENCHEN, Joseph ANTHONY, Jose Martin SOSA, Phillip You Fai LEE
-
Publication number: 20210199647Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.Type: ApplicationFiled: February 22, 2021Publication date: July 1, 2021Inventors: Nathan BECKETT, Gilad ALMOGY, Nathan CASWELL, Jacob A. WOLF, Kristopher BARBEE, Denis PRISTINSKI, Mark PRATT, Gene POLOVY, Osip SCHWARTZ, Stephanie KUBECKA, Steven MENCHEN, Joseph ANTHONY, Jose Martin SOSA, Phillip You Fai LEE
-
Publication number: 20210139980Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.Type: ApplicationFiled: January 22, 2021Publication date: May 13, 2021Inventors: Gilad ALMOGY, Nathan BECKETT, Jacob A. WOLF, Nathan CASWELL, Joseph ANTHONY, Jose Martin SOSA, Phillip LEE, Stephanie KUBECKA
-
Publication number: 20210079464Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.Type: ApplicationFiled: November 19, 2020Publication date: March 18, 2021Inventors: Nathan BECKETT, Gilad ALMOGY, Nathan CASWELL, Jacob A. WOLF, Kristopher BARBEE, Denis PRINTINSKI, Mark PRATT, Gene POLOVY, Osip SCHWARTZ, Stephanie KUBECKA, Steven MENCHEN, Joseph ANTHONY, Jose Martin SOSA, Phillip You Fai LEE
-
Patent number: 10900078Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.Type: GrantFiled: June 19, 2019Date of Patent: January 26, 2021Assignee: Ultima Genomics, Inc.Inventors: Gilad Almogy, Nathan Beckett, Jacob A. Wolf, Nathan Caswell, Joseph Anthony, Jose Martin Sosa, Phillip Lee, Stephanie Kubecka
-
Publication number: 20200291469Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.Type: ApplicationFiled: June 19, 2019Publication date: September 17, 2020Inventors: Gilad ALMOGY, Nathan BECKETT, Jacob A. WOLF, Nathan CASWELL, Joseph ANTHONY, Jose Martin SOSA, Phillip LEE, Stephanie KUBECKA
-
Patent number: D956263Type: GrantFiled: July 2, 2020Date of Patent: June 28, 2022Assignee: Ultima Genomics, Inc.Inventors: Nathan Beckett, Joseph Anthony, Phillip You Fai Lee, Jose Martin Sosa