Patents by Inventor Jose-Miguel Coteron

Jose-Miguel Coteron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound (S) and (R)-N-(2-fluoropyridin-4-yl)-3-methyl-2-(5-methyl-2,4-dioxo-1,2-dihydropyrido[3,4-d]pyrimidin-3(4H)-yl)butanamide and use
    Patent number: 9624219
    Abstract: The present invention relates to a compound of Formula (I) having pharmacological activity, processes for its preparation, pharmaceutical compositions and their use in the treatment of certain parasitic certain parasitic protozoal infections such as malaria, in particular infection by Plasmodium falciparum. (S)—N-(2-fluoropyridin-4-yl)-3-methyl-2-(5-methyl-2,4-dioxo-1,2-dihydropyrido[3,4-d]pyrimidin-3(4H)-yl)butanamide.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: April 18, 2017
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Jose-Miguel Coteron Lopez, Esther Pilar Fernandez Velando, Jorge Fernandez-Molina, Maria Luisa Leon-Diaz, David Matthew Wilson
  • Compound (S) and (R)-N-(2-fluoropyridin-4-yl)-3-methyl-2-(5-methyl-2,4-dioxo-1,2-dihydropyrido[3,4-d]pyrimidin-3(4H)-yl)butanamide and use
    Publication number: 20160311821
    Abstract: The present invention relates to a compound of Formula (I) having pharmacological activity, processes for its preparation, pharmaceutical compositions and their use in the treatment of certain parasitic certain parasitic protozoal infections such as malaria, in particular infection by Plasmodium falciparum. (S)-N-(2-fluoropyridin-4-yl)-3-methyl-2-(5-methyl-2,4-dioxo-1,2-dihydropyrido[3,4-d]pyrimidin-3(4H)-yl)butanamide.
    Type: Application
    Filed: April 19, 2016
    Publication date: October 27, 2016
    Inventors: Jose-Miguel COTERON LOPEZ, Esther Pilar FERNANDEZ VELANDO, Jorge FERNANDEZ-MOLINA, Maria Luisa LEON-DIAZ, David Matthew WILSON
  • PURINES AS CYSTEINE PROTEASE INHIBITORS
    Publication number: 20100105652
    Abstract: Substituted heteroaryl nitrile salt of Formula I, processes for their preparation, pharmaceutical compositions comprising such compounds and use of the compounds as cysteine protease inhibitors are provided.
    Type: Application
    Filed: February 28, 2008
    Publication date: April 29, 2010
    Inventors: Jose Miguel Coteron-Lopez, Beatriz Diaz-Hernandez, Jose Maria Fiandor-Roman, Maria Marco-Martin
  • NOVEL SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS
    Publication number: 20100009956
    Abstract: Substituted heteroaryl nitrile salts of Formula I, processes for their preparation, pharmaceutical compositions comprising such compounds and use of the compounds as cysteine protease inhibitors are provided.
    Type: Application
    Filed: October 26, 2007
    Publication date: January 14, 2010
    Inventors: Jose-Miguel Coteron Lopez, Jose Maria Fiandor Roman, Senthil Kumar Kusalakumari Sukumar
  • Morpholino ethers
    Patent number: 6410528
    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts and or metabolically labile derivatives thereof, wherein R1 represents C1-6 straight or branched chain alkyl, C1-6 straight or branched chain alkoxy, optionally substituted phenoxy, C3-6straight or branched chain alkenyloxy or C1-4 straight or branched alkoxy substituted by an optionally substituted phenyl group. C3-6 straight or branched chain alkenyl, optionally substituted phenyl, optionally substituted C3-7 cycloalkyl, C2-4 straight or branched chain alkyl substituted by (C1-4 alkoxy, C1-4 alkyl thio or halogen), C1-4 straight or branched chain alkyl substituted by (C1-4 alkoxycarbonyl, aryloxycarbonyl, cyano, optionally substituted C3-7 cycloalkyl, optionally substituted 5 or 6 membered heteroaryl, or 1 or 2 optionally substituted phenyl groups), a process for their preparation and their use in medicine.
    Type: Grant
    Filed: November 8, 2000
    Date of Patent: June 25, 2002
    Assignee: Glaxo Wellcome S.A.
    Inventors: Jose M. Bueno, Jesus Chicharro Gonzalo, Jose-Miguel Coteron, Juan Carlos Cuevas, Jose M. Fiandor, Araceli Mallo