Abstract: CRISPNA, a new tool for genome editing and diagnosis. The present invention relates to methods and systems for genome editing and diagnosis, and specifically relates to use of Peptide Nucleic Acids (PNAs) to direct the Cas proteins to their DNA or RNA targets.

Abstract: This disclosure provides a devices and systems for securing a gas turbine nozzle segment and sealing one or more cooling cavities of the gas turbine nozzle segment during manufacturing. The device can have a support assembly for receiving a nozzle segment having at least one cooling cavity. The device can have at least one clamp assembly configured to secure a first portion of the nozzle segment to the support assembly. The at least one clamp assembly having a first clamp arm, and a first tightening assembly coupling the first clamp arm to the support assembly. The device can have a first port seal assembly having at least one sealing member coupled to the first seal body and configured to interact with and seal the corresponding one or more cooling cavities.

Abstract: This disclosure provides a devices and systems for securing a gas turbine nozzle segment and sealing one or more cooling cavities of the gas turbine nozzle segment during manufacturing. The device can have a support assembly for receiving a nozzle segment having at least one cooling cavity. The device can have at least one clamp assembly configured to secure a first portion of the nozzle segment to the support assembly. The at least one clamp assembly having a first clamp arm, and a first tightening assembly coupling the first clamp arm to the support assembly. The device can have a first port seal assembly having at least one sealing member coupled to the first seal body and configured to interact with and seal the corresponding one or more cooling cavities.

Abstract: An apparatus for dynamic real time generation of interleaver sequences for a decoder includes a vector memory (210) that stores a plurality of vectors (212, 214, 216). Each vector (212, 214, 216) corresponds to a desired reordering of a matrix. A data memory (240) stores individual data elements (242) from a data stream (202) so that each data element (242) is stored in a different memory location in a predetermined order. An interleaver (220) circuit dynamically generates a plurality of interleaver elements (224), each in response to a request signal (226) (being asserted and each pointing to a memory location. A MAP decoder (260) receives the interleaver elements (224) from the interleaver circuit and retrieves the data element (242) stored in a memory location pointed to by each interleaver element (224).