Patents by Inventor Jose R. Pardinas

Jose R. Pardinas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6960438
    Abstract: Methods are provided for the isolation of newly synthesized mRNA. Such methods involve the incorporation of biotinylated rNTP analogues into cellular mRNA, and separating biotinylated mRNA from unlabeled RNA. The methods provided herein may be used, for example, for gene discovery, drug screens and studies of the regulation of gene expression.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: November 1, 2005
    Assignee: Signal Pharmaceuticals, LLC
    Inventors: Jose R. Pardinas, Kyle W. H. Chan
  • Publication number: 20030054332
    Abstract: Methods are provided for evaluating estrogenic and antiestrogenic effects of candidate therapeutic agents. Such methods are generally based on assays to detect modulation of estrogen-regulated marker expression in one or more specific cell types. Agents identified using such methods may be used, for example, in the prevention and treatmnt of diseases such as osteoporosis, cardiovascular disease and cancer.
    Type: Application
    Filed: May 10, 2001
    Publication date: March 20, 2003
    Inventors: Miguel S. Barbosa, Helen A. Brady, Kyle W.H. Chan, Jose R. Pardinas
  • Publication number: 20020146739
    Abstract: Methods are provided for the isolation of newly synthesized mRNA. Such methods involve the incorporation of biotinylated rNTP analogues into cellular mRNA, and separating biotinylated mRNA from unlabeled RNA. The methods provided herein may be used, for example, for gene discovery, drug screens and studies of the regulation of gene expression.
    Type: Application
    Filed: May 23, 2002
    Publication date: October 10, 2002
    Applicant: Signal Pharmaceuticals, Inc.
    Inventors: Jose R. Pardinas, Kyle W.H. Chan
  • Patent number: 6413720
    Abstract: Methods are provided for the isolation of newly synthesized mRNA. Such methods involve the incorporation of biotinylated rNTP analogues into cellular mRNA, and separating biotinylated mRNA from unlabeled RNA. The methods provided herein may be used, for example, for gene discovery, drug screens and studies of the regulation of gene expression.
    Type: Grant
    Filed: January 11, 1999
    Date of Patent: July 2, 2002
    Assignee: Signal Pharmaceuticals, Inc.
    Inventors: Jose R. Pardinas, Kyle W. H. Chan
  • Patent number: 6045998
    Abstract: The method of this invention relates to the use of improved anchor primers and a novel purification process to increase the efficiency and accuracy of the differential display technique.
    Type: Grant
    Filed: April 2, 1997
    Date of Patent: April 4, 2000
    Assignee: Johnson & Johnson Consumer Products, Inc.
    Inventors: Nicholas Combates, Jose R. Pardinas, Satish Parimoo, Stephen M. Prouty, Kurt S. Stenn