Patents by Inventor Jose Rafael Castillo

Jose Rafael Castillo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccine composition comprising interleukin-15 (il-15)
    Publication number: 20060182713
    Abstract: Vaccine composition containing IL-15 for active immunization to treatment diseases related to over-expression of this cytokine. The technical aim pursued in this invention is to inhibit IL-15 activity through development of a therapeutic vaccine which elicits IL-15 neutralizing antibodies in the immunized host. IL-15 can be presented in this vaccine composition either alone or coupled to a carrier such as the P64k protein with a vaccine adjuvant such as Aluminum hydroxide. Besides, this invention is related to the use of this vaccine for treatment of Rheumatoid arthritis and other IL-15 over-expressing related diseases, and leukemia, where this cytokine acts as a growth factor.
    Type: Application
    Filed: October 8, 2003
    Publication date: August 17, 2006
    Inventors: Alicia Savio, Ricardo Rodriguez, Yanelis Diaz, Armando Rodriguez Alfonso, Jose Rafael Castillo, Haydee Perez, Alejandro Soria, Silvio Rodriguez