Abstract: The invention relates to a method of isolating an immunoglobulin, comprising the steps of: a) providing a separation matrix comprising multimers of immunoglobulin-binding alkali-stabilized Protein A domains covalently coupled to a porous support: b) contacting a liquid sample comprising an immunoglobulin with the separation matrix; c) washing said separation matrix with a washing liquid; d) eluting the immunoglobulin from the separation matrix with an elution liquid, and e) cleaning the separation matrix with a cleaning liquid, wherein the alkali-stabilized Protein A domains comprise mutants of a parental Fc-binding domain of Staphylococcus Protein A (SpA).

Abstract: A method of foreign object debris discrimination incudes illuminating particulates located within a sensing volume with a first electromagnetic radiation pulse emitted from a first source, and illuminating the particulates within the sensing volume with a second electromagnetic radiation pulse emitted from a second source, wherein the second electromagnetic radiation pulse has a second wavelength range within the terahertz (THz) regime. The first electromagnetic radiation returns and the second electromagnetic radiation returns are compared to determine a scattering ratio from the comparing step. The scattering ratio is then utilized to determine a resultant foreign object debris type of the solid objects.

Abstract: Systems, apparatuses and methods may provide for technology that adjusts a plurality of weights in a neural network model and adjusts a plurality of activation functions in the neural network model. The technology may also output the neural network model in response to one or more conditions being satisfied by the plurality of weights and the plurality of activation functions. In one example, two or more of the activation functions are different from one another and the activation functions are adjusted on a per neuron basis.

Abstract: An assembly for a vehicle includes a substrate that defines a channel that has a bottom, a retention feature that is coupled to the substrate and that extends into the channel, and a panel that is operably coupled to the retention feature. The panel is movable between a locked position, wherein the panel is maintained in an upright position by the retention feature, and an unlocked position, wherein the panel is operable to pivot relative to the retention feature between the upright position and a stowed position.

Abstract: The present invention concerns a method of storing a separation matrix comprising multimers of immunoglobulin-binding alkali-stabilized Protein A domains covalently coupled to a porous support. The method comprises the steps of: a) providing a storage liquid comprising at least 50% by volume of an aqueous alkali metal hydroxide solution; b) permeating the separation matrix with the storage liquid; and c) storing the storage liquid-permeated separation matrix for a storage time of at least days.

Abstract: The invention relates to a separation matrix comprising at least 11 mg/ml Fc-binding ligands covalently coupled to a porous support, wherein: a) the ligands comprise multimers of alkali-stabilized Protein A domains, and b) the porous support comprises cross-linked polymer particles having a volume-weighted median diameter (d50, v) of 56-70 micrometers and a dry solids weight of 55-80 mg/ml.

Abstract: A separation system, a method in a separation system and an elution arrangement to be provided in a separation system for separating a biomolecule from a cell culture are provided. The method comprises the steps of: —providing a feed from a cell culture (3; 103; 203) comprising said biomolecule to a magnetic separator (5; 105; 205) and providing to the magnetic separator magnetic beads comprising ligands capable of binding this biomolecule; —separating by the magnetic separator said magnetic beads with bound biomolecules from the rest of the feed; —forwarding said magnetic beads as a slurry with an added buffer to an elution cell (7; 107; 207); —eluting the bound biomolecules in the elution cell.

Abstract: The invention relates to a method of isolating an immunoglobulin, comprising the steps of: a) providing a separation matrix comprising multimers of immunoglobulin-binding alkali-stabilized Protein A domains covalently coupled to a porous support, b) contacting a liquid sample comprising an immunoglobulin with the separation matrix, c) washing said separation matrix with a washing liquid, d) eluting the immunoglobulin from the separation matrix with an elution liquid, and e) cleaning the separation matrix with a cleaning liquid, wherein the alkali-stabilized Protein A domains comprise mutants of a parental Fc-binding domain of Staphylococcus Protein A (SpA), as defined by SEQ ID NO: 51 or SEQ ID NO: 52, wherein the amino acid residues at positions 13 and 44 of SEQ ID NO: 51 or 52 are asparagines and wherein at least the asparagine residue at position 3 of SEQ ID NO: 51 or 52 has been mutated to an amino acid selected from the group consisting of glutamic acid, lysine, tyrosine, threonine, phenylalanine, leuc

Abstract: A method and apparatus to estimate and mitigate platform noise incurred at a wireless device coupled to the platform. A computing device includes a platform including a first processor, a wireless device coupled to the platform, the wireless device including a second processor, and a plurality of antennas coupled to the wireless device. At least one of the first processor or the second processor is configured to determine characteristics of a platform noise incurred at the wireless device in real-time due to utilization of circuitries and processing components on the platform and implement an adaptive real-time and application/context-aware measure to mitigate the platform noise based on the determined characteristics of the platform noise.

Abstract: A light emitting diode display panel may comprise a substrate, a plurality of light emitting diodes located over the substrate, and an optical assembly located over the plurality of light emitting diodes. The optical assembly may include a lens array and a diffuser. An inner surface of the lens array may define a plurality of inner curves.

Abstract: A component of an Autonomous Vehicle (AV) system, the component having at least one processor; and a non-transitory computer-readable storage medium including instructions that, when executed by the at least one processor, cause the at least one processor to decode data encoded in a signal, wherein the data identifies a pattern of protrusions embedded in a driving surface, the signal being received from at least one vehicle sensor resulting from a vehicle driving over the pattern of protrusions in the driving surface.

Abstract: A method of foreign object debris discrimination includes illuminating a particle located within a sensing volume with a modulated electromagnetic radiation pulse emitted from a source; receiving one or more electromagnetic radiation return signals that have been scattered by the particle illuminated by the modulated electromagnetic radiation pulse at a detector; mixing, using a controller, the electromagnetic radiation return signal of amplitude IRS and frequency fRS with a reference signal of amplitude ILS and frequency fRS; analyzing, using the controller, an amplitude of the mixed signal ?{square root over (ILSIRS)}, and frequency of the mixed signal, fRS?fLS; and classifying, using the controller, a particle position, a velocity, and electromagnetic characteristic of the particle based on the amplitude, ?{square root over (ILSIRS)}, and frequency, fRS?fLS of the mixed signal.

Abstract: The subject disclosure describes, among other things, illustrative embodiments of an impact protection device that comprises the following elements: a machine, a protective structural member, and a fluid holding member. The impact protection device is designed to protect a user from an impact to the protective structural member by dissipating a portion of the kinetic energy of the impact. Machine operation translates into a controlled movement between elements of the impact protection device that deform the fluid holding member, thereby displacing a fluid. This controlled movement also dictates a throttling profile that regulates the amount of damping; thereby managing the portion of kinetic energy dissipated. The machine can be a mechanical assembly incorporating levers, cams and or computerized controllers.

Abstract: This disclosure describes systems, methods, and devices related to reducing noise in and improving speech signals and radio signals. A device may identify a radio frequency signal received by radio frequency circuity at a time; apply a Short Time Fourier Transform (STFT) to the radio frequency signal to generate a STFT signal; identify a signal-to-noise ratio associated with the radio frequency signal at the time; identify a packet-error-rate associated with the radio frequency signal at the time; identify activity when the multiplexed radio frequency signal is received by the radio frequency circuity at the time; select, based on the signal-to-noise ratio, the packet-error-rate, and the activity, a spectral mask to be applied to the STFT signal; apply the selected spectral mask to the STFT signal to generate a clean STFT signal; and apply an inverse STFT to the clean STFT signal to generate a clean radio frequency signal.

Abstract: Techniques are disclosed to use existing vehicle speakers alone or in conjunction with other sensors (e.g. SRS sensors and/or microphones) that may already be implemented as part of the vehicle to identify acoustic signatures. Suitable low-cost and widely available hardware components (e.g., relays) may be used to modify the vehicle's existing speakers for a bi-directional mode of operation. Moreover, the vehicle's existing of audio amplifiers may be used to amplify signals collected by the speakers when operating in “reverse,” and process these collected signals to determine vehicle state information.

Abstract: Various antennas elements including antennas arrays can support various communication technologies and can be integrated into different components or subcomponents of a vehicle, including various vehicle light assemblies. The vehicular antennas elements include low profile and/or concealed antenna elements that are inconspicuous aesthetically and do not affect or substantially affect vehicle aerodynamics.

Abstract: Monodirectional antennas may be arranged to radiate in a near omni-directional pattern. By incorporating switches into the antenna arrangement, the antennas can be controlled to selectively radiate from a common radiofrequency feed. These arrangements may be packaged in a housing, which may aid both in antenna performance and in antenna installation. According to another aspect of the disclosure, housings may include a plurality of antennas, and one or more procedures may be implemented to determine a codebook to radiate from the circular arrangement according to various beam constrains.

Abstract: A radio frequency front end and an antenna front end may be separated from one another to maintain close proximity between a low noise amplifier and an antenna while achieving improved thermal regulation of a power amplifier. The radio frequency front end antenna front end may include a duplexing system that enables operation with a single electrical cable. Furthermore, where it is desired to transmit a radiofrequency signal via a waveguide, a flexible waveguide may be constructed with a distributed capacitance between waveguide protrusions.

Abstract: Methods, apparatus, systems, and articles of manufacture are disclosed. An example apparatus includes at least one memory; instructions; and processor circuitry to execute the instructions. The processor circuitry executes the instructions to extract static and dynamic data from a packet associated with a request for service by an edge device, the static data to change less frequently than the dynamic data. The processor circuitry executes the instructions to generate a first plurality of probability distributions using the static data. The processor circuitry executes the instructions to generate a second plurality of probability distributions using the dynamic data. The processor circuitry executes the instructions to calculate a confidence value for a first helper compute unit of a plurality of helper compute units, the confidence value. The processor circuitry executes the instructions to assign the first helper compute unit the request for service based on the confidence value.

Abstract: A system, article, and method of detection of acoustic source aiming direction uses multiple microphones.