Patents by Inventor Jose S. Franzone

Jose S. Franzone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4868186
    Abstract: New derivatives of theophylline are described, which have the general formula: ##STR1## in which R is selected from the group consisting of 2'-(1'-oxy-1', 3'-dithiolanyl), 2'-(1', 3'-dithiolanyl) and 2'-(1',3'-dithianyl), possibly substituted in position 4'. The derivatives have high antibronchospastic, antitussive and mucolytic activities.
    Type: Grant
    Filed: December 24, 1987
    Date of Patent: September 19, 1989
    Assignee: Istituto Biologico Chemioterapico ABC S.p.A.
    Inventors: Jose S. Franzone, Sergio De Vercelli
  • Patent number: 4378359
    Abstract: Compounds of the following general formula ##STR1## wherein: X and Y are different from each other and represent --CH.sub.2 -- or an oxygen atom; R represents a radical selected from hydroxy, bromo, acetoxy, pyrrolidino, morpholino, piperazino and piperazino substituted at the position 4 by a carbethoxy, benzyl, phenyl, halophenyl, methoxyphenyl or trifluoromethylphenyl group, or when X is --CH.sub.2 -- and Y is an oxygen atom, R may represent also chloro; methods for their preparation; pharmaceutical compositions containing them. The compounds possess a remarkable antitussive activity.
    Type: Grant
    Filed: April 6, 1981
    Date of Patent: March 29, 1983
    Assignees: Istituto Biologico Chemioterapico "ABC" S.p.A., Unibios S.p.A
    Inventors: Ugo Chiodoni, Jose S. Franzone, Silvano Spinelli
  • Patent number: 4285962
    Abstract: Pharmaceutical compositions are described which exhibit anti-ulcer activity. They contain as the active ingredient an effective amount of 5-methoxy-2-methyl-3-indolylacetohydroxamic acid of formula I ##STR1## The compositions are suitable for oral administration. The compositions are particularly useful for treatment of ulcers caused by other pharmaceuticals such as pharmaceuticals of the steroid type, but not limited to pharmaceuticals of the steroid type.
    Type: Grant
    Filed: August 25, 1980
    Date of Patent: August 25, 1981
    Assignee: Istituto Biologico Chemioterapico "ABC" S.p.A.
    Inventor: Jose S. Franzone
  • Patent number: 4187308
    Abstract: A pharmaceutical composition with anti-bronchospasmodic and anti-tussive activity which contains an effective amount of the compound of formula ##STR1## together with at least one pharmaceutically acceptable carrier or diluent. The composition may be administered orally, parenterally, rectally or by means of an aerosol.
    Type: Grant
    Filed: October 12, 1978
    Date of Patent: February 5, 1980
    Assignee: Istituto Biologico Chemioterapico "ABC" S.p.A.
    Inventors: Jose S. Franzone, Teresio Tamietto