Patents by Inventor Jose T. Baselga

Jose T. Baselga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of phosphoinositide 3-kinase inhibitors for treatment of vascular malformations
    Patent number: 10864215
    Abstract: The present disclosure relates to methods of treating a vascular malformation in a subject expressing a gain-of-function mutation in a PIK3CA gene comprising administering, to the subject, an effective amount of an agent that inhibits phosphoinositide 3-kinase (“PI3K”).
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: December 15, 2020
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Eulalia Baselga, Pau Castel, Jose T. Baselga
  • COMBINATION THERAPY USING PDK1 AND PI3K INHIBITORS
    Publication number: 20180147232
    Abstract: The present invention relates to methods and compositions for inhibiting growth and proliferation of cancer cells resistant to PI3K inhibition using a combination of PDK1, SGK1 and PI3K inhibitors. The present invention is also directed to methods of treating cancer in a subject exhibiting cancer cells resistant to PI3K inhibition, comprising administering inhibitors of PI3K in combination with inhibitors of PDK1 and/or SGK1 to the subject.
    Type: Application
    Filed: January 17, 2018
    Publication date: May 31, 2018
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Pau Castel, Jose T. Baselga, Maurizio Scaltriti
  • USE OF PHOSPHOINOSITIDE 3-KINASE INHIBITORS FOR TREATMENT OF VASCULAR MALFORMATIONS
    Publication number: 20180117055
    Abstract: The present disclosure relates to methods of treating a vascular malformation in a subject expressing a gain-of-function mutation in a PIK3CA gene comprising administering, to the subject, an effective amount of an agent that inhibits phosphoinositide 3-kinase (“PI3K”).
    Type: Application
    Filed: November 14, 2017
    Publication date: May 3, 2018
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Eulalia Baselga, Pau Castel, Jose T. Baselga