Patents by Inventor Jose VELADA CALZADA

Jose VELADA CALZADA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11911509
    Abstract: The present invention relates to a pharmaceutical composition comprising a therapeutically effective dose of Lenvatinib mesylate having sodium wherein the weight ratio of Lenvatinib mesylate to sodium carbonates ranges from 1:1.5 to 1:5.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: February 27, 2024
    Assignee: Synthon B.V.
    Inventors: Luis Nogueiras Nieto, Lisardo Alvarez Fernandez, Jose Velada Calzada, Rohit Kumar
  • Patent number: 11529353
    Abstract: The present invention relates to a pharmaceutical granulate composition comprising Palbociclib free base, having improved bioavailability.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: December 20, 2022
    Assignee: Synthon B.V.
    Inventors: Marta Vivancos Martinez, Lisardo Alvarez Fernandez, Rohit Kumar, Jose Velada Calzada
  • Patent number: 11517536
    Abstract: The present invention relates to a pharmaceutical composition comprising pomalidomide, maltodextrin and a filler, wherein the weight ratio of maltodextrin to filler ranges from 1:1 to 1:2. The invention further relates to the use of said pharmaceutical composition as medicament in the treatment of multiple myeloma.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: December 6, 2022
    Assignee: Synthon B.V.
    Inventors: Sonia Garcia Jimenez, Luis Nogueiras Nieto, Lisardo Alvarez Fernandez, Jose Velada Calzada
  • Patent number: 11007152
    Abstract: The present invention relates to a pharmaceutical composition comprising amorphous lenalidomide, or a pharmaceutically acceptable salt thereof, with a synthetic antioxidant and one or more pharmaceutically acceptable excipients. The invention further relates to the process to manufacture such a compositions and the use of said composition as a medicament, particularly in the treatment of in the treatment of multiple myeloma and myelodyplastic syndromes.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: May 18, 2021
    Assignee: Synthon B.V.
    Inventors: Marta Vivancos Martinez, Lisardo Alvarez Fernandez, Jose Velada Calzada
  • Publication number: 20200188380
    Abstract: The present invention relates to a pharmaceutical composition comprising a therapeutically effective dose of Lenvatinib mesylate having sodium wherein the weight ratio of Lenvatinib mesylate to sodium carbonates ranges from 1:1.5 to 1:5.
    Type: Application
    Filed: April 4, 2018
    Publication date: June 18, 2020
    Inventors: Luis NOGUEIRAS NIETO, Lisardo ALVAREZ FERNANDEZ, Jose VELADA CALZADA, Rohit KUMAR
  • Publication number: 20200147089
    Abstract: The present invention relates to a pharmaceutical granulate composition comprising Palbociclib free base, having improved bioavailability.
    Type: Application
    Filed: July 25, 2018
    Publication date: May 14, 2020
    Inventors: Marta VIVANCO MARTINEZ, Lisardo ALVAREZ FERNANDEZ, Rohit KUMAR, Jose VELADA CALZADA
  • Patent number: 10588892
    Abstract: The present invention relates to a pharmaceutical composition comprising a physical mixture of sacubitril sodium and valsartan disodium, wherein the X-ray powder diffraction pattern of valsartan disodium comprises characteristic peaks at the following 2 theta (±0.2) angles: 4.70°, 9.29°, 22.34°, measured using a Cu K? radiation. The invention further relates to the use of said pharmaceutical composition as medicament in the treatment of heart failure.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: March 17, 2020
    Assignee: SYNTHON B.V.
    Inventors: Bohumil Dymacek, Marta Vivancos Martinez, Luis Nogueiras Nieto, Lisardo Alvarez Fernandez, Rohit Kumar, Jose Velada Calzada, Petr Mitas
  • Patent number: 10543174
    Abstract: The present invention relates to a pharmaceutical composition, particularly a modified release tablet composition comprising mirabegron or a pharmaceutically acceptable salt thereof and to a process for preparing such a composition.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: January 28, 2020
    Assignee: Synthon B.V.
    Inventors: Agnes Fernandez Pena, Jose Velada Calzada, Rohit Kumar, Lisardo Alvarez Fernandez
  • Patent number: 10478399
    Abstract: The present invention relates to a pharmaceutical composition, particularly a modified release tablet composition comprising mirabegron or a pharmaceutically acceptable salt thereof and to a process for preparing such a composition.
    Type: Grant
    Filed: October 12, 2017
    Date of Patent: November 19, 2019
    Assignee: Synthon B.V.
    Inventors: Agnes Fernandez Pena, Onne Peter Hilbert Backers, Jose Velada Calzada
  • Publication number: 20190307696
    Abstract: The present invention relates to a pharmaceutical multi layer tablet comprising a controlled release part with mirabegron and an immediate release part wherein the immediate release formulation comprises: solifenacin succinate and a water insoluble diluent in an amount of 50 to 99% w/w relative to the total weight of the immediate release part of the tablet. The invention further relates to the use of said composition as a medicament, particularly in the treatment of urinary incontinence.
    Type: Application
    Filed: April 21, 2017
    Publication date: October 10, 2019
    Inventors: Agnes FERNANDEZ PENA, Jose VELADA CALZADA, Rohit KUMAR, Lisardo ALVAREZ FERNANDEZ
  • Publication number: 20190240157
    Abstract: The present invention relates to a pharmaceutical composition comprising amorphous lenalidomide, or a pharmaceutically acceptable salt thereof, with a synthetic antioxidant and one or more pharmaceutically acceptable excipients. The invention further relates to the process to manufacture such a compositions and the use of said composition as a medicament, particularly in the treatment of in the treatment of multiple myeloma and myelodyplastic syndromes.
    Type: Application
    Filed: April 18, 2019
    Publication date: August 8, 2019
    Inventors: Marta VIVANCOS MARTINEZ, Lisardo ALVAREZ FERNANDEZ, Jose VELADA CALZADA
  • Patent number: 10328028
    Abstract: The present invention relates to a pharmaceutical composition comprising amorphous lenalidomide, or a pharmaceutically acceptable salt thereof, with a synthetic antioxidant and one or more pharmaceutically acceptable excipients. The invention further relates to the process to manufacture such a compositions and the use of said composition as a medicament, particularly in the treatment of in the treatment of multiple myeloma and myelodyplastic syndromes.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: June 25, 2019
    Assignee: Synthon B.V.
    Inventors: Marta Vivancos Martinez, Lisardo Alvarez Fernandez, Jose Velada Calzada
  • Publication number: 20190183805
    Abstract: The present invention relates to a pharmaceutical composition comprising pomalidomide, maltodextrin and a filler, wherein the weight ratio of maltodextrin to filler ranges from 1:1 to 1:2. The invention further relates to the use of said pharmaceutical composition as medicament in the treatment of multiple myeloma.
    Type: Application
    Filed: July 28, 2017
    Publication date: June 20, 2019
    Applicant: Synthon BV
    Inventors: Sonia GARCIA JIMENEZ, Luis NOGUEIRAS NIETO, Lisardo ALVAREZ FERNANDEZ, Jose VELADA CALZADA
  • Publication number: 20190133957
    Abstract: The present invention relates to a pharmaceutical composition, particularly a modified release tablet composition comprising mirabegron or a pharmaceutically acceptable salt thereof and to a process for preparing such a composition.
    Type: Application
    Filed: April 21, 2017
    Publication date: May 9, 2019
    Inventors: Agnes FERNANDEZ PENA, Jose VELADA CALZADA, Rohit KUMAR, Lisardo ALVAREZ FERNANDEZ
  • Publication number: 20190110995
    Abstract: The present invention relates to a pharmaceutical composition, particularly a modified release tablet composition comprising mirabegron or a pharmaceutically acceptable salt thereof and to a process for preparing such a composition
    Type: Application
    Filed: October 12, 2017
    Publication date: April 18, 2019
    Inventors: Agnes FERNANDEZ PENA, Onne Peter Hilbert BACKERS, Jose VELADA CALZADA
  • Publication number: 20190030000
    Abstract: The present invention relates to a pharmaceutical composition comprising a physical mixture of sacubitril sodium and valsartan disodium, wherein the X-ray powder diffraction pattern of valsartan disodium comprises characteristic peaks at the following 2 theta (±0.2) angles: 4.70°, 9.29°, 22.34°, measured using a Cu K? radiation. The invention further relates to the use of said pharmaceutical composition as medicament in the treatment of heart failure.
    Type: Application
    Filed: July 26, 2018
    Publication date: January 31, 2019
    Inventors: Bohumil DYMACEK, Marta VIVANCOS MARTINEZ, Luis NOGUEIRAS NIETO, Lisardo ALVAREZ FERNANDEZ, Rohit KUMAR, Jose VELADA CALZADA, Petr MITAS
  • Publication number: 20180256501
    Abstract: The present invention relates to a pharmaceutical composition comprising amorphous lenalidomide, or a pharmaceutically acceptable salt thereof, with a synthetic antioxidant and one or more pharmaceutically acceptable excipients. The invention further relates to the process to manufacture such a compositions and the use of said composition as a medicament, particularly in the treatment of in the treatment of multiple myeloma and myelodyplastic syndromes.
    Type: Application
    Filed: May 14, 2018
    Publication date: September 13, 2018
    Inventors: Marta VIVANCOS MARTINEZ, Lisardo ALVAREZ FERNANDEZ, Jose VELADA CALZADA