Abstract: A process for the manufacture of Sevoflurane CF3—CH(OCH2F)—CF3 which comprises (a) manufacturing a substituted malonic acid derivative of formula (I): R1OOC—CH(OCH2X)—COOR2 or of formula (II): R3HNOC—CH(OCH2X)—CONHR4, wherein X is OH or a leaving group which can be substituted by nucleophilic substitution and wherein R1, R2 R3, R4, equal to or different from each other, are independently selected from the group consisting of H, an alkyl group having from 1 to 10 carbon atoms which is optionally substituted by at least one halogen atom, an aralkyl group, and an aryl group; and (b) further reacting said malonic acid derivative as intermediate for the manufacture of Sevoflurane CF3—CH(OCH2F)—CF3.

Abstract: N-Thio-anthranilamid compounds of formula (I) wherein A is a group selected from A1 and A2 wherein the variables and the indices are as defined per the description, processes for preparing the compounds I, pesticidal compositions comprising compounds I, use of compounds I for the control of insects, acarids or nematodes, and methods for treating, controlling, preventing or protecting animals against infestation or infection by parasites by use of compounds of formula I.

Abstract: N-Thio-anthranilamid compounds of formula (I) wherein A is a group selected from A1 and A2 wherein the variables and the indices are as defined per the description, processes for preparing the compounds I, pesticidal compositions comprising compounds I, use of compounds I for the control of insects, acarids or nematodes, and methods for treating, controlling, preventing or protecting animals against infestation or infection by parasites by use of compounds of formula I.

Abstract: The present invention relates to isoxazoline compounds which are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.

Abstract: Esters of 4-fluorosubstituted 3-oxo-alcanoic acids can be prepared by addition reaction of ketene with the respective acid chloride, subsequent esterification and hydrodechlorination. Preferred reaction products are esters of 4,4-difluoro-3-oxo-butanoic acid.

Abstract: The present invention relates to polypeptides, preferably from Drosophila melanogaster (DmShaI) as target for insecticides.

Abstract: The present invention relates to imine compounds which are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.

Abstract: The invention relates to substituted amidine compounds of formula (I), to the enantiomers, diastereomers and salts thereof and to compositions comprising such compounds. The invention also relates to the use of the substituted amidine compounds, of their salts or of compositions comprising them for combating animal pests. Furthermore the invention relates also to methods of applying such substituted amidine compounds. The substituted amidine compounds of the present invention are defined by the following formula I: wherein A1 to A4, B1 to B3, R1 to R3, (R4)p, (R5)q, X and Y are defined as in the description.

Abstract: A high voltage controller configured to drive a high voltage generator. The high voltage controller includes a voltage select input and a current select input, an actual voltage input and an actual current input. First circuitry is configured to generate an alternating current (AC) drive signal. Second circuitry configured to generate a direct current (DC) drive signal. Closed loop control circuitry is configured to adjust the DC drive signal based on at least one of the voltage select and current select inputs and at least one of the actual voltage and actual current inputs. The first circuitry may include a push-pull circuit. The second circuitry may include a pulse width modulation (PWM) controller. A high voltage generator may be coupled to the AC and DC drive signals. The high voltage generator may include a high voltage transformer having a pair of primary windings and center tap. The AC drive signal may be coupled to the primary windings and the DC drive signal may be coupled to the center tap.

Abstract: The invention relates to a system and method called autotopology of a network or advertising based network management which enables the analysis and automatic graphical and hierarchical representation of any hierarchical or flat network topology, especially a switched Ethernet (SE). The autotopology can be used for self-configured networks (for example by using zeroconf) and for any otherwise configured networks, especially using DHCP or manually configured networks. The use of zeroconf is called autoconfiguration. Autoconfiguration and autotopology enable a comfortable and safe administration of a network. Administration of a self-configured network using the autotopology data proceeds in a separate and low-priority sub-network (link local) so that the productive operation of the network remains undisturbed. The topology of the network is used as a clear possibility of administering a network. Administration of the network is possible immediately after determination of the topology.

Abstract: The present invention relates to a method of combating animal pests which comprises contacting the animal pest, their habit, breeding ground, food supply, plant, seed, soil, area, material or environment in which the animal pests are growing or may grow, or the materials, plants, seeds, soils, surfaces or spaces to be protected from animal attack or infestation, with a pesticidally effective amount of at least one 1-(1,2-diphenyl-ethyl)-3-(2-hydroxyethyl)-thiourea compound I or an agriculturally acceptable salt thereof, wherein m is 0 to 5, n is 0 to 5, R3 and R4 are H or optionally substituted alkyl, haloalkyl, cycloalkyl, phenyl or benzyl, R7, R8, R9 and R10 are H or optionally substituted C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkylamino, C1-C6-alkoxy, C3-C6-cycloalkyl, phenyl or benzyl and the variables R1, R2, R5 and R6 are as defined in the claims.

Abstract: The invention relates to a system and method called autotopology of a network or advertising based network management which enables the analysis and automatic graphical and hierarchical representation of any hierarchical or flat network topology, especially a switched Ethernet (SE). The autotopology can be used for self-configured networks (for example by using zeroconf) and for any otherwise configured networks, especially using DHCP or manually configured networks. The use of zeroconf is called autoconfiguration. Autoconfiguration and autotopology enable a comfortable and safe administration of a network. Administration of a self-configured network using the autotopology data proceeds in a separate and low-priority sub-network (link local) so that the productive operation of the network remains undisturbed. The topology of the network is used as a clear possibility of administering a network. Administration of the network is possible immediately after determination of the topology.

Abstract: A flat sealing ring (1) for producing a fluid-tight coupling of two surfaces which are to be sealed against one another by means of a contact force, the ring (1) having an elastically deformable base ring (2), wherein a stiffening ring (3, 3′, 3″) is provided at at least one of the inner circumferential edge of the base ring (2) or the outer circumferential edge of the base ring (2), wherein the stiffening ring, at least perpendicularly to the ring plane, has a lesser deformability, or greater firmness, than the base ring (2), and wherein the height of the stiffening ring perpendicularly to the ring plane is less than the greatest height of the base ring (2) perpendicularly to the ring plane.

Abstract: The present invention provides a transdermal drug delivery composition comprising:(a) a copolymer of one or more (meth)acrylate monomers being selected from the group consisting of alkyl acrylates containing 4 to 12 carbon atoms in the alkyl group and alkyl methacrylates containing 4 to 12 carbon atoms in the alkyl group and one or more hydrophilic monomers being copolymerizable with said (meth)acrylate monomers, and(b) a therapeutically effective amount of lerisetron. The transdermal drug delivery composition is used to make a transdermal drug delivery device for the delivery of lerisetron.

Abstract: A transdermal drug delivery device involving an acrylate or methacrylate based adhesive copolymer, a skin penetration enhancer, and a therapeutically effective amount of alfuzosin.

Abstract: Transdermal drug formulations containing a prostaglandin, optionally a lipophilic excipient, and a polyisobutylene pressure sensitive adhesive.

Abstract: Transdermal drug formulations containing a prostaglandin, optionally a lipophilic excipient, and a polyisobutylene pressure sensitive adhesive.

Abstract: A tube or pipe connector of plastic for corrugated pipes or tubes is adapted to be folded open in the axial direction, comprises two half members connected via a film hinge and provided with a detent member for mutual locking of the half members, and at least one portion which is adapted to receive corrugated pipe and the interior of which is formed to match the outer periphery of the corrugated pipe. The pipe connector is provided with a tube piece which has a thread and a stop member is provided which has an outer diameter greater than the outer diameter of the tube piece. Furthermore, a tube connector of plastic is proposed for corrugated pipes of different outer diameter, and a divisible nut of plastic for such tube connectors serves for securing the threaded tube pieces.

Abstract: In an annularly corrugated flexible plastic protective tube or conduit for receiving lines the longitudinal slit thereof is so widened that it is readily possible to insert the lines without interference. Clamped in fitting manner on the tube is an outer tube which also has a wide longitudinal slot and which covers the longitudinal slot of the first tube. The locking engagement of inner and outer tubes can be improved by corresponding complementary formation of the ribs or corrugations of the tubes. Branch pieces can be clamped onto the inner and outer tubes.

Abstract: A retention nozzle is provided at the catch side of the weaving machine for clamping or retaining the weft thread end during severance of the weft thread by means of a shear. A transfer nozzle is also provided at the catch side. When the weft thread lies over the transfer nozzle after being severed, the transfer nozzle is supplied with blower air and subsequently the supply of blower air to the retention nozzle is interrupted. In this manner the weft thread end is withdrawn from a catch channel of the retention nozzle and blown into a catch channel of the transfer nozzle. During this operation, the weft thread end is conducted through an eyelet of a selvedge-laying needle and thereby transferred to the latter. The retention nozzle permits severance of the weft thread by means of the shear even before the weft thread is in alignment with the eyelet of the selvedge-laying needle and the transfer nozzle.