Patents by Inventor Josef Dieckhoff

Josef Dieckhoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyanocobalamin acid hydrazides and their conjugates
    Patent number: 5171679
    Abstract: The present invention provides cobalamin acid hydrazides of the general formula:B--CO--NH--NH--R--CO--NH--NH).sub.x H (I)wherein B is a residue formed from a cobalamin by the splitting off of a --CONH.sub.2 group, R is a spacer and x is 0 or 1, as well as a process for the preparation thereof.The present invention also provides cobalamin conjugates of the general formula:B--d--CO--NH--NH--R--CO--NH).sub.x N.dbd.GP (II)in which B, R and x have the above-given meanings and d signifies the position of --CO--NH--, as well as a process for the preparation thereof. These cobalamin conjugates are very suitable for use in immunoassays, especially for the determination of cyanocobalamin.
    Type: Grant
    Filed: January 5, 1990
    Date of Patent: December 15, 1992
    Assignee: Boehringer Mannheim GmbH
    Inventors: Erasmus Huber, Josef Dieckhoff, Christian Klein, Konrad Kurzinger