Patents by Inventor Josef Gottfried Meingassner

Josef Gottfried Meingassner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic depsipeptides
    Patent number: 9127044
    Abstract: The present application relates to cyclic depsipeptides, or derivatives thereof, having the structure of formula (I), and uses thereof, e.g. as inhibitors of kallikrein 7 and human neutrophil elastase.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: September 8, 2015
    Assignee: NOVARTIS AG
    Inventors: Philipp Krastel, Brigitta-Maria Liechty, Josef Gottfried Meingassner, Esther Schmitt, Erwin Paul Schreiner
  • Kallikrein 7 modulators
    Patent number: 8309596
    Abstract: The present invention relates to the crystal structure of the serine protease kallikrein 7 and to the use of this crystal structure in drug discovery. The present invention also relates to compounds binding specifically to this active site of kallikrein 7.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: November 13, 2012
    Assignee: Novartis AG
    Inventors: Stefanie Flohr, Stefan Andreas Randl, Nils Ostermann, Ulrich Hassiepen, Frederic Berst, Ursula Bodendorf, Bernd Gerhartz, Andreas Marzinzik, Claus Ehrhardt, Josef Gottfried Meingassner
  • CYCLIC DEPSIPEPTIDES
    Publication number: 20120196790
    Abstract: The present application relates to cyclic depsipeptides, or derivatives thereof, having the structure of formula (I), and uses thereof, e.g. as inhibitors of kallikrein 7 and human neutrophil elastase.
    Type: Application
    Filed: February 14, 2012
    Publication date: August 2, 2012
    Applicant: NOVARTIS AG
    Inventors: Philipp KRASTEL, Brigitta-Maria LIECHTY, Josef Gottfried MEINGASSNER, Esther SCHMITT, Erwin Paul SCHREINER
  • Cyclic depsipeptides
    Patent number: 8178650
    Abstract: The present application relates to cyclic depsipeptides, or derivatives thereof, having the structure of formula (I), and uses thereof, e.g. as inhibitors of kallikrein 7 and human neutrophil elastase.
    Type: Grant
    Filed: August 18, 2008
    Date of Patent: May 15, 2012
    Assignee: Novartis AG
    Inventors: Philipp Krastel, Brigitta-Maria Liechty, Josef Gottfried Meingassner, Esther Schmitt, Erwin Paul Schreiner
  • Pharmaceutical Compositions and Solid Forms
    Publication number: 20110112121
    Abstract: The present invention relates to pharmaceutical compositions of 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide, to the use of 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide and compositions of 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide in therapeutic applications, especially indications with a dysregulation/overexpression of VEFG, (neo)-vascularisation and VEGF driven angiogenesis and to methods for manufacturing such compositions, the invention further relates to specific forms of 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide and to the manufacturing and use of such forms. The present invention also relates to a new process to produce 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide.
    Type: Application
    Filed: June 30, 2010
    Publication date: May 12, 2011
    Inventors: Joerg BERGHAUSEN, Claire HAUG, Michael HERBIG, Bin HU, Stéphane JONAT, Rajender LELETI, Josef Gottfried MEINGASSNER, Stéphanie MONNIER, Matthias NAPP, Mahavir PRASHAD, Anton STÜTZ, Ranjit THAKUR
  • Kallikrein 7 modulators
    Publication number: 20100256144
    Abstract: The present invention relates to the crystal structure of the serine protease kallikrein 7 and to the use of this crystal structure in drug discovery. The present invention also relates to compounds binding specifically to this active site of kallikrein 7.
    Type: Application
    Filed: June 26, 2008
    Publication date: October 7, 2010
    Inventors: Stefanie Flohr, Stefan Andreas Randl, Nils Ostermann, Ulrich Hassiepen, Frederic Berst, Ursula Bodendorf, Bernd Gerhartz, Adreas Marzinzik, Claus Ehrhardt, Josef Gottfried Meingassner
  • ANTI-INFLAMMATORY COMPOUNDS
    Publication number: 20090227620
    Abstract: The use of a steroid sulfatase inhibitor in the preparation of a medicament for the treatment of inflammatory diseases.
    Type: Application
    Filed: March 15, 2006
    Publication date: September 10, 2009
    Inventor: Josef Gottfried Meingassner
  • Combination of a Steroid Sulfatase Inhibitor and an Ascomycin
    Publication number: 20080293758
    Abstract: A combination of a steroid sulfatase inhibitor and an ascomycin, which combination is useful as a pharmaceutical.
    Type: Application
    Filed: March 15, 2006
    Publication date: November 27, 2008
    Applicant: Novartis AG
    Inventor: Josef Gottfried Meingassner
  • Antiinflammatory lactones
    Patent number: 7414074
    Abstract: Lactones of Formula (I) which are pharmaceutically active in diseases associated with inflammation
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: August 19, 2008
    Assignee: Novartis AG
    Inventors: Josef Gottfried Meingassner, Klaus Thirring
  • Use Of A Steroid For Enhancement Of Skin Permeability
    Publication number: 20080171729
    Abstract: A method for enhancing skin permeability by administration of a tetracyclic compound and improved methods for treatment of disorders by administration of a tetracyclic compound and a pharmaceutically active compound.
    Type: Application
    Filed: July 15, 2005
    Publication date: July 17, 2008
    Inventor: Josef Gottfried Meingassner
  • Melvinolin derivatives
    Patent number: 6818638
    Abstract: Mevinolin derivatives wherein the lactone ring is modified have interesting pharmaceutical properties, particularly in preventing or treating disorders or diseases mediated by LFA-1/ICAM-1 interactions.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: November 16, 2004
    Assignee: Novartis AG
    Inventors: Rolf Baenteli, Wilfried Bauer, Sylvain Cottens, Claus Ehrhardt, Ulrich Hommel, Jörg Kallen, Josef Gottfried Meingassner, François Nuninger, Gabriele Weitz Schmidt
  • Macrolides containing pharmaceutical compositions
    Publication number: 20040192716
    Abstract: A pharmaceutical compound comprising a compound of formula I and a pharmaceutically acceptable 2-amino-1,3-propanediol beside one or more pharmaceutically acceptable excipient(s).
    Type: Application
    Filed: April 13, 2004
    Publication date: September 30, 2004
    Inventor: Josef Gottfried Meingassner
  • Use of mglur5 antagonists for the treatment of pruritic conditions
    Publication number: 20040106582
    Abstract: The invention provides the use of mGluR5 receptor antagonists for the treatment of pruritic conditions.
    Type: Application
    Filed: July 14, 2003
    Publication date: June 3, 2004
    Inventors: Fabrizio Gasparini, Laszlo Urban, Josef Gottfried Meingassner
  • Mevinolin derivatives
    Publication number: 20030087903
    Abstract: Mevinolin derivatives wherein the lactone ring is modified have interesting pharmaceutical properties, particularly in preventing or treating disorders or diseases mediated by LFA-1/ICAM-1 interactions.
    Type: Application
    Filed: July 11, 2002
    Publication date: May 8, 2003
    Inventors: Rolf Baenteli, Wilfried Bauer, Sylvain Cottens, Claus Ehrhardt, Ulrich Hommel, Jorg Kallen, Josef Gottfried Meingassner, Francois Nuninger, Gabriele Weitz Schmidt
  • Mevinolin derivatives
    Publication number: 20020037895
    Abstract: Mevinolin derivatives wherein the lactone ring is modified have interesting pharmaceutical properties, particularly in preventing or treating disorders or diseases mediated by LFA-1/ICAM-1 interactions.
    Type: Application
    Filed: August 13, 2001
    Publication date: March 28, 2002
    Inventors: Rolf Baenteli, Wilfried Bauer, Sylvain Cottens, Claus Ehrhardt, Ulrich Hommel, Joerg Kallen, Josef Gottfried Meingassner, Francois Nuninger, Gabriele Weitz Schmidt
  • Antifungal composition
    Patent number: 5985906
    Abstract: Use of a combination of the squalene epoxidase inhibitor terbinafine and an azole 14-alpha-methyldemethylase inhibitor (fluconazole or itraconazole) in mycotic infections caused by azole-resistant fungal strains, and corresponding pharmaceutical compositions, process and method.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: November 16, 1999
    Assignee: Novartis AG
    Inventors: Josef Gottfried Meingassner, Neil Stewart Ryder
  • Use of 11,28-dioxa-4-azatricyclo[22.3.1.0.sup.4,9 ]octacos-18-ene derivatives and pharmaceutical compositions containing them
    Patent number: 5665727
    Abstract: The compounds of formula I, ##STR1## have been found to have excellent topical activity. They are thus indicated for use in the topical treatment of inflammatory and hyperpoliferative skin diseases and of cutaneous manifestations of immunologically-induced illnesses, such as psoriasis.
    Type: Grant
    Filed: August 15, 1994
    Date of Patent: September 9, 1997
    Assignee: Sandoz Ltd.
    Inventors: Maximilian Grassberger, Josef Gottfried Meingassner, Anton Stutz, Peter Stutz