Patents by Inventor Josef Heveling

Josef Heveling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030149285
    Abstract: The invention relates to a method for producing 1,1′ binaphthalenylidene-4,4′-diones of general formula (I), wherein R1 represents C1-6 alkyl, C1-6 alkoxy, phenyl, substituted phenyl, benzyl or benzyloxy; R2, R3, R4, and R5 independently of one another represent hydrogen, C1-6 alkyl, C1-6 alkoxy, phenyl, substituted phenyl, benzyl or benzyloxy. Production takes place by oxidative coupling of the corresponding naphthols in the presence of a peroxide and a precious metal catalyst.
    Type: Application
    Filed: November 18, 2002
    Publication date: August 7, 2003
    Inventors: Michael Hauck, Josef Heveling, Alain Wellig
  • Patent number: 6469178
    Abstract: A new process for the catalytic conversion of hydroxymethyl imidazoles to formylimidazoles is described. The reaction takes place in the presence of a peroxide. Formylimidazoles are important intermediate products for pharmaceutical substances.
    Type: Grant
    Filed: December 5, 2001
    Date of Patent: October 22, 2002
    Assignee: Lonza AG
    Inventors: Yves Bessard, Josef Heveling
  • Publication number: 20020045760
    Abstract: A new process for the catalytic conversion of hydroxymethyl imidazoles to formylimidazoles is described. The reaction takes place in the presence of a peroxide. Formylimidazoles are important intermediate products for pharmaceutical substances.
    Type: Application
    Filed: December 5, 2001
    Publication date: April 18, 2002
    Applicant: Lonza AG
    Inventors: Yves Bessard, Josef Heveling
  • Publication number: 20010014743
    Abstract: A new process for the catalytic conversion of hydroxymethyl imidazoles to formylimidazoles is described. The reaction takes place in the presence of a peroxide. Formylimidazoles are important intermediate products for pharmaceutical substances.
    Type: Application
    Filed: March 29, 2001
    Publication date: August 16, 2001
    Applicant: Lonza AG
    Inventors: Yves Bessard, Josef Heveling
  • Patent number: 6258958
    Abstract: A new procedure for the catalytic conversion of hydroxy methyl imidazoles to formyl imidazoles is described. The catalysis takes place in the presence of a peroxide. Formyl imidazoles are important intermediate products for pharmaceutical substances.
    Type: Grant
    Filed: December 11, 2000
    Date of Patent: July 10, 2001
    Assignee: Lonza AG
    Inventors: Yves Bessard, Josef Heveling
  • Patent number: 6080865
    Abstract: Methyl-5-(3-methyl piperidino)pentanamines of general formula ##STR1## in which one of the two radicals R.sup.1, R.sup.2 is hydrogen and the other methyl, are produced by two-stage hydrogenation from 2-methyl glutaronitrile. The compounds are suitable as catalysts in the production of polyurethanes.
    Type: Grant
    Filed: October 20, 1997
    Date of Patent: June 27, 2000
    Assignee: Lonza AG
    Inventors: Josef Heveling, Andreas Gerhard
  • Patent number: 6075145
    Abstract: Catalyst compositions based on amorphous partially dehydrated zirconium hydroxide which are doped with from 0.01 to 20 atom percent of copper and/or from 0.01 to 20 atom percent of nickel, in each case based on zirconium, and have a specific surface area by the BET method of at least 50 m.sup.2 /g. The catalyst compositions are suitable, in particular, as the catalyst in hydrogen transfer reactions, such as, the Meerwein-Ponndorf-Verley reduction or the Oppenauer oxidation. The preparation of 3-hydroxyquinuclidine of the formula: ##STR1## involves reaction of quinuclidin-3-one with a secondary alcohol in the presence of the amorphous partially dehydrated zirconium hydroxide.
    Type: Grant
    Filed: March 6, 1998
    Date of Patent: June 13, 2000
    Assignee: Lonza AG
    Inventors: Josef Heveling, David Laffan, Alain Wellig
  • Patent number: 6054497
    Abstract: A process for the synthesis of methanol on X-ray amorphous catalysts with a copper, zinc and zirconium oxide content in relative proportions of 10 to 70 weight percent of copper, 10 to 50 weight percent of zinc and 20 to 80 weight percent of zirconium. The process for the synthesis of methanol is distinguished by high space time yields.
    Type: Grant
    Filed: June 10, 1998
    Date of Patent: April 25, 2000
    Assignee: Lonza, A.G.
    Inventors: Alkis Sofianos, Erich Armbruster, Olaf Frei, Josef Heveling
  • Patent number: 6040457
    Abstract: A process for the catalytic conversion of hydroxymethylimidazoles to formylimidazoles. The catalysis takes place in the presence of a peroxide. Formylimidazoles are important intermediates for pharmaceutical active ingredients.
    Type: Grant
    Filed: November 16, 1998
    Date of Patent: March 21, 2000
    Assignee: Lonza AG
    Inventors: Josef Heveling, Alain Wellig
  • Patent number: 5917051
    Abstract: A process for the catalytic conversion of halogenated hydroxymethylimidazoles to halogenated formylimidazoles. The catalysis takes place in the presence of a peroxide. Halogenated formylimidazoles are important intermediates for pharmaceutical active ingredients.
    Type: Grant
    Filed: October 23, 1998
    Date of Patent: June 29, 1999
    Assignee: Lonza, AG
    Inventors: Josef Heveling, Alain Wellig
  • Patent number: 5719045
    Abstract: A process for preparing nicotinamide, wherein, in the first stage, 2-methyl-1,5-diaminopentane is catalytically converted into 3-picoline, then the 3-picoline is converted via an ammonoxidation into 3-cyanopyridine and, finally, the 3-cyanopyridine is converted microbiologically into the nicotinamide.
    Type: Grant
    Filed: October 31, 1996
    Date of Patent: February 17, 1998
    Assignee: Lonza AG
    Inventors: Josef Heveling, Erich Armbruster, Lukas Utiger, Markus Rohner, Hans-Rudolf Dettwiler, Roderick J. Chuck
  • Patent number: 5714610
    Abstract: In a process for preparing 3-methylpiperidine or 3-methylpyridine from 2-methyl-1,5-diaminopentane in the gaseous phase, the initial product is made to flow over catalysts. In the first step, 3-methylpiperidine is produced, and if required 3-methylpyridine is produced in a second step.
    Type: Grant
    Filed: November 2, 1995
    Date of Patent: February 3, 1998
    Assignee: Lonza Ltd.
    Inventors: Josef Heveling, Erich Armbruster, Walter Siegrist
  • Patent number: 5698607
    Abstract: Tertiary diamines having two saturated heterocyclic rings joined by an aliphatic carbon chain, of the general formula ##STR1## in which each A is a two- to four-membered aliphatic carbon chain substituted if desired by one or more C.sub.1 -C.sub.4 -alkyl groups, are prepared in one stage by catalytic hydrogenation of the corresponding dinitriles of the general formulaN.tbd.C--A--C.tbd.N IIThe diamines preparable in accordance with the invention are particularly suitable as catalysts for the production of polyurethanes.
    Type: Grant
    Filed: January 30, 1997
    Date of Patent: December 16, 1997
    Assignee: Lonza AG
    Inventors: Josef Heveling, Andreas Gerhard, Ulrich Daum
  • Patent number: 5310952
    Abstract: A novel process for the preparation of aminochromans of the general formula: ##STR1## wherein R is a C.sub.1 -C.sub.4 alkyl group. In the process, a nitrochromanone of the general formula: ##STR2## is hydrogenated with hydrogen in the presence of a hydrogenation catalyst. The resultant aminochromanone (III) is reduced using zirconium oxide/isopropanol to the aminochromene (IV). The latter is finally hydrogenated with hydrogen in the presence of a hydrogenation catalyst to give the final product. The aminochromans are useful intermediates for the preparation of hypolipidaemic pharmaceuticals.
    Type: Grant
    Filed: February 19, 1993
    Date of Patent: May 10, 1994
    Assignees: Lonza Ltd., Sankyo Company Ltd.
    Inventor: Josef Heveling
  • Patent number: 5284961
    Abstract: A novel process for the preparation of aminochromans of the general formula: ##STR1## wherein R is a lower alkyl group having 1 to 4 carbon atoms. In the process, nitrochromanones of the general formula: ##STR2## are reduced using zirconium oxide/isopropanol to give a mixture of a corresponding aminochromene: ##STR3## and a corresponding nitrochromene: ##STR4## The mixture is then hydrogenated with hydrogen in the presence of a hydrogenation catalyst to give the final product. The aminochromans are important intermediates for the preparation of hypolipidaemic pharmaceuticals.
    Type: Grant
    Filed: February 19, 1993
    Date of Patent: February 8, 1994
    Assignees: Lonza Ltd., Sankyo Company, Ltd.
    Inventor: Josef Heveling