Patents by Inventor Josef Manasku

Josef Manasku has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of reprocessing quaternary ammonium-containing neuromuscular blocking agents
    Publication number: 20060009485
    Abstract: Provided is a method for reprocessing neuromuscular blocking agents containing a quaternary ammonium salt, e.g., Rocuronium bromide, using a novel dealkylation method. The process is effective in obtaining a highly pure product from a contaminated starting material by heating, optionally in the presence of an organic solvent, to produce a dealkyated product. The dealkylated product is purified, e.g., by crystallization, and converted by any known method to a stable, highly-pure neuromuscular blocking agent.
    Type: Application
    Filed: June 23, 2005
    Publication date: January 12, 2006
    Applicant: CHEMAGIS LTD
    Inventors: Oded Friedman, Oded Arad, Tamir Fizitzki, Josef Manasku, Joseph Kaspi