Patents by Inventor Josef Pfeilschifter

Josef Pfeilschifter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serum Biomarker For Hepatocellular Carcinoma (HCC)
    Publication number: 20180113135
    Abstract: The present invention pertains to novel diagnostic procedures for the prognosis, diagnosis and monitoring of liver diseases such as hepatocellular carcinoma (HCC). The present invention provides sphingolipids and especially long chain ceramides as significant and highly prognostic serum biomarkers in HCC compared to liver cirrhosis. Therefore the invention in particular provides a method for detecting the presence or absence of a HCC in a liver cirrhosis patient using the disclosed biomarkers. Also provided is a method for monitoring the treatment success of a HCC treatment by monitoring the disclosed serum biomarkers. Finally the invention pertains to diagnostic kits for performing the disclosed methods of the invention.
    Type: Application
    Filed: April 8, 2016
    Publication date: April 26, 2018
    Inventors: Georgios Grammatikos, Josef Pfeilschifter, Stefan Zeuzem, Nerea Ferreirós
  • Novel Heterocyclic Compounds as Modulators of Sphingolipid Signaling and Uses Thereof
    Publication number: 20140100248
    Abstract: The present invention relates to new heterocyclic compounds as modulators of sphingolipid signaling and uses thereof of as pharmaceutically active agents, suitable for treating proliferative, degenerative, infectious, and other diseases.
    Type: Application
    Filed: April 2, 2012
    Publication date: April 10, 2014
    Applicants: UNIVERSITÄT BERN, JOHANN WOLFGANG GOETHE-UNIVERSITÄT
    Inventors: Holger Stark, Aleksandra Zivkovic, Andrea Huwiler, Josef Pfeilschifter