Patents by Inventor Josehp G. Bruno

Josehp G. Bruno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel HMG-CoA reductase inhibitors
    Patent number: 4904692
    Abstract: Disclosed are novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula ##STR1## and the corresponding ring-opened hydroxy acids derived therefrom and pharmaceutically acceptable salts thereof.Pharmaceutical compositions containing said compounds and method of inhibiting the biosynthesis of cholesterol therewith are also disclosed.
    Type: Grant
    Filed: December 12, 1988
    Date of Patent: February 27, 1990
    Assignee: Rorer Pharmaceutical Corporation
    Inventors: John R. Regan, Josehp G. Bruno, Kent W. Neuenschwander, Donald E. Kuhla