Patents by Inventor Josep Castells Boliart

Josep Castells Boliart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EXOPOLYSACCHARIDE-PROTEIN COMPLEX, A METHOD OF PREPARING SAID COMPLEX AND USES THEREOF
    Publication number: 20220160610
    Abstract: The present invention relates to an exopolysaccharide-protein complex obtained from a bacterium comprising: (i) a crude exopolysaccharide, and (ii) exopolysaccharide-associated proteins which are derived from outer membrane vesicles and have a molecular weight between 30 and 250 kDa. The present invention further relates to a method for preparing said exopolysaccharide-protein complex and uses thereof.
    Type: Application
    Filed: January 6, 2022
    Publication date: May 26, 2022
    Inventors: Víctor Manuel DERONCELÉ THOMAS, Rafael MONTILLA AREVALO, Josep CASTELLS BOLIART, Adrián GARCÍA DE LA MARINA
  • Exopolysaccharide-protein complex, a method of preparing said complex and uses thereof
    Patent number: 11253457
    Abstract: The present invention relates to an exopolysaccharide-protein complex obtained from a bacterium comprising: (i) a crude exopolysaccharide, and (ii) exopolysaccharide-associated proteins which are derived from outer membrane vesicles and have a molecular weight between 30 and 250 kDa. The present invention further relates to a method for preparing said exopolysaccharide-protein complex and uses thereof.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: February 22, 2022
    Assignee: INSTITUT UNIV. DE CIÈNCIA I TECNOLOGIA, S.A.
    Inventors: Victor Manuel Deroncelé Thomas, Rafael Montilla Arevalo, Josep Castells Boliart, Adrián García de la Marina
  • COMPOUNDS FOR USE IN PREVENTING OR TREATING CANCER
    Publication number: 20210230150
    Abstract: The present invention relates to compounds of formula (I) for use in preventing and/or treating cancer.
    Type: Application
    Filed: July 1, 2019
    Publication date: July 29, 2021
    Inventors: Josep ROMA CASTANYER, Marta PASCUAL GILABERT, José SÁNCHEZ DE TOLEDO CODINA, Soledad GALLEGO MELCÓN, Patricia ZARZOSA MARTÍNEZ, Javier ALONSO FERNÁNDEZ, Sergio PÉREZ OZCÁRIZ, Cristina LÓPEZ GÓMEZ, Josep CASTELLS BOLIART
  • EXOPOLYSACCHARIDE-PROTEIN COMPLEX, A METHOD OF PREPARING SAID COMPLEX AND USES THEREOF
    Publication number: 20190209452
    Abstract: The present invention relates to an exopolysaccharide-protein complex obtained from a bacterium comprising: (i) a crude exopolysaccharide, and (ii) exopolysaccharide-associated proteins which are derived from outer membrane vesicles and have a molecular weight between 30 and 250 kDa. The present invention further relates to a method for preparing said exopolysaccharide-protein complex and uses thereof.
    Type: Application
    Filed: September 19, 2017
    Publication date: July 11, 2019
    Inventors: Víctor Manuel DERONCELÉ THOMAS, Rafael MONTILLA AREVALO, Josep CASTELLS BOLIART, Adrián GARCÍA DE LA MARINA
  • Compounds for the treatment of myotonic dystrophy
    Patent number: 10226467
    Abstract: The present invention relates to a compound of formula (I), provided that this compound is not caffeine, for use in the treatment of myotonic dystrophy type 1 and type 2. The present invention also relates to compositions comprising the compound of formula (I). The present invention further relates to new compounds which are dimers of compounds of formula (I).
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: March 12, 2019
    Assignees: Universitat de Valencia, Institut Quimic de Sarria Cets Fundacio Privada, Institut Univ. de Ciencia I Tecnologia, S.A.
    Inventors: Ruben Artero Allepuz, Josep Castells Boliart, José Ignacio Borrell Bilbao, Beatriz Llamusi Troísi, Ariadna Bargiela Schönbrunn, Piotr Konieczny, Marta Pascual Gilabert, Jordi Teixidó Closa, Roger Estrada Tejedor, Alejandro López González
  • DEAMINATION OF ORGANOPHOSPHORUS-NUCLEOSIDES
    Publication number: 20180066295
    Abstract: The invention relates to a new synthetic process for obtaining compounds of formula (I) from compounds of formula (II) by means of cytidine deaminase enzymes.
    Type: Application
    Filed: March 18, 2016
    Publication date: March 8, 2018
    Inventors: Sergio PÉREZ OZCÁRIZ, Marta PASCUAL GILABERT, Carmen María FERNÁNDEZ FERNÁNDEZ, Josep CASTELLS BOLIART, Javier ALONSO FERNÁNDEZ, Cristina LÓPEZ GÓMEZ
  • COMPOUNDS FOR THE TREATMENT OF MYOTONIC DYSTROPHY
    Publication number: 20170312285
    Abstract: The present invention relates to a compound of formula (I), provided that this compound is not caffeine, for use in the treatment of myotonic dystrophy type 1 and type 2. The present invention also relates to compositions comprising the compound of formula (I). The present invention further relates to new compounds which are dimers of compounds of formula (I).
    Type: Application
    Filed: November 13, 2015
    Publication date: November 2, 2017
    Inventors: Ruben ARTERO ALLEPUZ, Josep CASTELLS BOLIART, José Ignacio BORRELL BILBAO, Beatriz LLAMUSI TROÍSI, Ariadna BARGIELA SCHÖNBRUNN, Piotr KONIECZNY, Marta PASCUAL GILABERT, Jordi TEIXIDÓ CLOSA, Roger ESTRADA TEJEDOR, Alejandro LÓPEZ GONZÁLEZ
  • CAFFEINE FOR THE TREATMENT OF MYOTONIC DYSTROPHY TYPE 1 AND TYPE 2
    Publication number: 20170304309
    Abstract: The present invention relates to caffeine for use in the treatment of myotonic dystrophy type 1 and type 2. The present invention also relates to compositions comprising caffeine for use in the treatment of myotonic dystrophy type 1 and type 2.
    Type: Application
    Filed: November 13, 2015
    Publication date: October 26, 2017
    Inventors: Ruben ARTERO ALLEPUZ, Josep CASTELLS BOLIART, José Ignacio BORRELL BILBAO, Beatriz LLAMUSI TROÍSI, Ariadna BARGIELA SCHÖNBRUNN, Piotr KONIECZNY, Marta PASCUAL GILABERT, Jordi TEIXIDÓ CLOSA, Roger ESTRADA TEJEDOR, Alejandro LÓPEZ GONZÁLEZ
  • Formulation, preparation and use of a glycerol-based biofuel
    Patent number: 9708560
    Abstract: The present invention relates to a new biofuel formulation comprising: crude glycerol, glycerol formal, optionally at least one fatty acid glycerol formal ester and optionally at least one fatty acid methyl ester. The present invention also relates to a process for its preparation and its use for burning purposes.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: July 18, 2017
    Assignee: Institut Univ. de Ciencia I Tecnologia, S.A.
    Inventors: Carles Estévez Company, Natividad Bayarri Ferrer, Josep Castells Boliart
  • FORMULATION, PREPARATION AND USE OF A GLYCEROL-BASED BIOFUEL
    Publication number: 20150353855
    Abstract: The present invention relates to a new biofuel formulation comprising: crude glycerol, glycerol formal, optionally at least one fatty acid glycerol formal ester and optionally at least one fatty acid methyl ester. The present invention also relates to a process for its preparation and its use for burning purposes.
    Type: Application
    Filed: January 16, 2014
    Publication date: December 10, 2015
    Applicant: INSTITUT UNIV.DE CIÈNCIA I TECNOLOGIA, S. A.
    Inventors: Carles ESTÉVEZ COMPANY, Natividad BAYARRI FERRER, Josep CASTELLS BOLIART
  • PROCESS FOR MANUFACTURING BIOFUELS
    Publication number: 20150307794
    Abstract: The present invention relates to a process for obtaining simultaneously several compositions comprising fatty acid alkyl esters (biodiesel), glycerol formal and fatty acid glycerol formal esters.
    Type: Application
    Filed: November 8, 2013
    Publication date: October 29, 2015
    Inventors: Carles Estevez Company, Natividad Bayarri Ferrer, Josep Castells Boliart
  • Process for manufacturing biofuels
    Patent number: 9157039
    Abstract: The present invention relates to a process for obtaining simultaneously several compositions comprising fatty acid alkyl esters (biodiesel), glycerol formal and fatty acid glycerol formal esters.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: October 13, 2015
    Assignee: INSTITUT UNIV. DE CIÈNCIA I TECHNOLOGIA, S.A.
    Inventors: Carles Estevez Company, Natividad Bayarri Ferrer, Josep Castells Boliart
  • Degreasing compositions derived from levulinic acid (a compound obtainable from biomass) and process for degreasing metal surfaces
    Patent number: 8834635
    Abstract: The present invention relates to a new degreasing composition comprising at least one levulinic acid ester according to general formula (I) CH3CO(CH2)2COOR1 (I) in which R1 is a linear or branched, saturated or unsaturated, aliphatic or aromatic, hydrocarbon radical having 2 to 56 carbon atoms, wherein said hydrocarbon radical is optionally hydroxysubstituted. The present invention also relates to a process for degreasing a metal surface comprising the step of contacting said metal surface with the composition of the present invention.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: September 16, 2014
    Assignee: Institut Univ. de Ciencia Tecnologia, S.A.
    Inventors: Natividad Bayarri Ferrer, Lidia Galià Prats, Carles Estévez Company, Josep Castells Boliart
  • -substituted--phenylethylsulfonamides for the identification of biological and pharmacological activity
    Patent number: 8809584
    Abstract: Novel compounds are continually sought after to treat and prevent diseases and disorders. The invention relates to N-substituted-N-phenylethylsulfonamides useful for being biologically and pharmacologically screened, and to contribute to the exploration and identification of new lead molecules that are capable of modulating the functional activity of a biological target.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: August 19, 2014
    Assignee: Institut Univ. de Ciencia i Tecnologia, S.A.
    Inventors: Josep Castells Boliart, David Enrique Miguel Centeno, Marta Pascual Gilabert
  • Thermostable biocatalyst combination for nucleoside synthesis
    Patent number: 8759034
    Abstract: A recombinant expression vector comprising: a) the sequence encoding a purine nucleoside phosphorylase (PNPase, E. C. 2.4.2.1), b) the sequence encoding a uridine phosphorylase (UPase, E. C. 2.4.2.3), c) or both; each of the sequences operably linked to one or more control sequences that direct the production of said phosphorylases in a suitable expression host; said sequences originating from the Archaea Thermoprotei class, characterized in that the PNPase is from Sulfolobus solfataricus (SEQ ID NO. 7) and the UPase is from Aeropyrum pernix (SEQ ID NO. 8). In addition, the present invention relates to A transglycosylation method between a sugar-donating nucleoside and an acceptor base in the presence of phosphate ions, characterized in that said method comprises the use of a uridine phosphorylase (UPase) of Aeropyrum pernix (NC_000854.2), a purine nucleoside phosphorylase (PNpase) of Sulfolobus solfataricus (NC_002754.1), or a combination thereof.
    Type: Grant
    Filed: July 22, 2013
    Date of Patent: June 24, 2014
    Assignee: Plasmia Biotech, S.L.
    Inventors: Rafael Montilla Arevalo, Victor Manuel DeronceléThomas, Cristina López Gómez, Marta Pascual Gilabert, Carlos Estevez Company, Josep Castells Boliart
  • DEGREASING COMPOSITIONS DERIVED FROM LEVULINIC ACID (A COMPOUND OBTAINABLE FROM BIOMASS) AND PROCESS FOR DEGREASING METAL SURFACES
    Publication number: 20140123998
    Abstract: The present invention relates to a new degreasing composition comprising at least one levulinic acid ester according to general formula (I) CH3CO(CH2)2COOR1 (I) in which R1 is a linear or branched, saturated or unsaturated, aliphatic or aromatic, hydrocarbon radical having 2 to 56 carbon atoms, wherein said hydrocarbon radical is optionally hydroxysubstituted. The present invention also relates to a process for degreasing a metal surface comprising the step of contacting said metal surface with the composition of the present invention.
    Type: Application
    Filed: June 28, 2012
    Publication date: May 8, 2014
    Applicant: INSTITUT UNIV. DE CIÈNCIA I TECNOLOGIA, S. A.
    Inventors: Natividad Bayarri Ferrer, Lidia Galià Prats, Carles Estévez Company, Josep Castells Boliart
  • THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS
    Publication number: 20130337547
    Abstract: A recombinant expression vector comprising: a) the sequence encoding a purine nucleoside phosphorylase (PNPase, E. C. 2.4.2.1), b) the sequence encoding a uridine phosphorylase (UPase, E. C. 2.4.2.3), c) or both; each of the sequences operably linked to one or more control sequences that direct the production of said phosphorylases in a suitable expression host; said sequences originating from the Archaea Thermoprotei class, characterized in that the PNPase is from Sulfolobus solfataricus (SEQ ID NO. 7) and the UPase is from Aeropyrum pernix (SEQ ID NO. 8). In addition, the present invention relates to A transglycosylation method between a sugar-donating nucleoside and an acceptor base in the presence of phosphate ions, characterised in that said method comprises the use of a uridine phosphorylase (UPase) of Aeropyrum pernix (NC_000854.2), a purine nucleoside phosphorylase (PNpase) of Sulfolobus solfataricus (NC_002754.1), or a combination thereof.
    Type: Application
    Filed: July 22, 2013
    Publication date: December 19, 2013
    Inventors: Rafael Montilla Arevalo, Victor Manuel Deroncelé Thomas, Cristina López Gómez, Marta Pascual Gilabert, Carlos Estevez Company, Josep Castells Boliart
  • -(2-oxo-1-phenylpiperidin-3-yl)sulfonamides for the identification of biological and pharmacological activity
    Patent number: 8569507
    Abstract: Novel compounds are continually sought after to treat and prevent diseases and disorders. The invention relates to N-(2-oxo-1-phenylpiperidin-3-yl)sulfonamides useful for being biologically and pharmacologically screened, and to contribute to the exploration and identification of new lead molecules that are capable of modulating the functional activity of a biological target.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: October 29, 2013
    Assignee: Institut Univ. De Ciencia I Technologia, S.A.
    Inventors: Josep Castells Boliart, David Enrique Miguel Centeno, Marta Pascual Gilabert
  • Thermostable biocatalyst combination for nucleoside synthesis
    Patent number: 8512997
    Abstract: The present invention relates to a recombinant expression vector comprising: a) the sequence encoding a purine nucleoside phosphorylase (PNPase, E. C. 2.4.2.1), b) the sequence encoding a uridine phosphorylase (UPase, E. C. 2.4.2.3), c) or both; each of the sequences operably linked to one or more control sequences that direct the production of said phosphorylases in a suitable expression host; said sequences originating from the Archaea Thermoprotei class, characterized in that the PNPase is from Sulfolobus solfataricus (SEQ ID NO. 7) and the UPase is from Aeropyrum pernix (SEQ ID NO. 8). In addition, the present invention relates to A transglycosylation method between a sugar-donating nucleoside and an acceptor base in the presence of phosphate ions, characterised in that said method comprises the use of a uridine phosphorylase (UPase) of Aeropyrum pernix (NC_000854.2), a purine nucleoside phosphorylase (PN-Pase) of Sulfolobus solfataricus (NC_002754.1), or a combination thereof.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: August 20, 2013
    Assignee: Plasmia Biotech, S.L.
    Inventors: Rafael Montilla Arevalo, Víctor Manuel Deroncelé Thomas, Cristina López Gómez, Marta Pascual Gilabert, Carlos Estévez Company, Josep Castells Boliart
  • 1-(sulfonyl)--phenylpyrrolidine-2-carboxamides for the identification of biological and pharmacological activity
    Patent number: 8455660
    Abstract: Novel compounds are continually sought after to treat and prevent diseases and disorders. The invention relates to 1-(sulfonyl)-N-phenylpyrrolidine-2-carboxamides which are useful for being biologically and pharmacologically screened, and to contribute to the exploration and identification of new lead molecules that are capable of modulating the functional activity of a biological target.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: June 4, 2013
    Assignee: Institut Univ. de Ciencia i Tecnologia, S.A.
    Inventors: Josep Castells Boliart, David Enrique Miguel Centeno, Marta Pascual Gilabert