Patents by Inventor Josep M. Castello

Josep M. Castello has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7635691
    Abstract: The invention describes a prophylactic treatment of cerebral ischemia with CDP-Choline in patients who have undergone major surgery or are at risk of suffering an acute ischemic event.
    Type: Grant
    Filed: May 20, 2005
    Date of Patent: December 22, 2009
    Assignee: Ferrer Internacional, S.A.
    Inventors: Rafael Foguet, Jorge Ramentol, Isidro J. Ferrer, Rafael Lozano, Julio J. Secades, Manuel M. Raga, Josep M. Castello, José A. Ortiz
  • Patent number: 6930096
    Abstract: The invention describes the prophylactic treatment of cerebral ischemia with CDP-Choline in patients who have undergone major surgery or are at risk of suffering an acute ischemic event.
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: August 16, 2005
    Assignee: Ferrer Internacional, S.A.
    Inventors: Rafael Foguet, Jorge Ramentol, Isidro J. Ferrer, Rafael Lozano, Julio J. Secades, Manuel M. Raga, Josep M. Castello, José A. Ortiz
  • Patent number: 6894032
    Abstract: The invention relates to the use of CDP-Choline or its pharmaceutically acceptable salts for the preparation of a medicinal product for the treatment of alcohol withdrawal syndrome at daily doses equivalent to 0.5-2 g of free CDP-Choline.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: May 17, 2005
    Assignee: Ferrer Internacional, S.A.
    Inventors: Rafael Foguet, Jorge Ramentol, Rafael Lozano, Julián Agut, Jesús Torres, Manuel M. Raga, Josep M. Castello, José A. Ortiz
  • Patent number: 6881845
    Abstract: The present invention relates to a process for preparing (±)-trans-4-p-fluorophenyl-3-hyroxymethyl-1-methylpiperdine of formula (I). The present invention also relates to novel intermediates of the formula (IX) and (IX?) methods for preparing said intermediates and the use of said compounds for preparing Paroxetine and Omiloxetine.
    Type: Grant
    Filed: January 4, 2001
    Date of Patent: April 19, 2005
    Assignee: Ferrer Internacional, S.A.
    Inventors: Rafael Foguet, Jorge Ramentol, Diego Fernandez-Cano, Miguel P. Armengol, Inés Petschen, Juan Sallares, Francesc X. Camps, Manuel M. Raga, Josep M. Castello
  • Publication number: 20040215020
    Abstract: The present invention relates to a process for preparing (±)-trans-4-p-fluorophenyl-3-hyroxymethyl-1-methylpiperdine of formula (I). The present invention also relates to novel intermediates of the formula (IX) and (IX′) methods for preparing said intermediates and the use of said compounds for preparing Paroxetine and Omiloxetine.
    Type: Application
    Filed: September 15, 2003
    Publication date: October 28, 2004
    Inventors: Rafael Foguet, Jorge Ramentol, Diego Fernandez-Cano, Miguel P. Armengol, Ines Petschen, Juan Sallares, Francesc X. Camps, Manuel M. Raga, Josep M. Castello
  • Publication number: 20030162749
    Abstract: The invention relates to the use of CDP-Choline or its pharmaceutically acceptable salts for the preparation of a medicinal product for the treatment of alcohol withdrawal syndrome at daily doses equivalent to 0.5-2 g of free CDP-Choline.
    Type: Application
    Filed: September 30, 2002
    Publication date: August 28, 2003
    Inventors: Rafael Foguet, Jorge Ramentol, Rafael Lozano, Julian Agut, Jesus Torres, Manuel M. Raga, Josep M. Castello, Jose A. Ortiz
  • Patent number: 6348605
    Abstract: 3-(Hydroxymethyl)chromen-4-ones of formula (I) are described and a process for preparing said compounds.
    Type: Grant
    Filed: June 14, 2001
    Date of Patent: February 19, 2002
    Assignee: Ferrer Internacional, S.A.
    Inventors: Rafael Foguet, Jordi Bolos, Aurelio Sacristan, Josep M. Castello, José A. Ortiz
  • Patent number: 6187793
    Abstract: 7-[3-[4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl]propoxy]-chromen-4-one derivatives having the formula (I): wherein R is hydrogen, CHO, CH2OR2 or COOH; R1 is hydrogen or CH2OH; and R2 is alkyl having 1 to 4 carbon atoms with the proviso that one of substituents R and R1 should be hydrogen, as well as their pharmaceutically acceptable salts. The process for their preparation and the pharmaceutical compositions containing them are also described. The compounds are new and are useful in the treatment of psychosis, schizophrenia and allergy.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: February 13, 2001
    Assignee: Ferrer Internacional, S.A.
    Inventors: Rafael Foguet, Jordi Bolós, Aurelio Sacristán, Josep M. Castelló, José A. Ortiz
  • Patent number: 6005115
    Abstract: Two forms of N-[[[2-[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]ethyl]amino] methylene]-4-bromo-benzenesulfonamidehave been identified. A process for the preparation of thereof and the use thereof are described.
    Type: Grant
    Filed: July 3, 1996
    Date of Patent: December 21, 1999
    Assignee: Ferrer Internacional, S.A.
    Inventors: Rafael Foguet, Lluis Anglada, Jose A. Ortiz, Aurelio Sacristan, Josep M. Castello
  • Patent number: 5852021
    Abstract: Polymorph B of (1-diphenylmethyl)-4-?3-(2-phenyl-1,3-dioxolan-2-yl)propyl!piperazine have been identified. A process for its preparation and its use are described.
    Type: Grant
    Filed: December 27, 1996
    Date of Patent: December 22, 1998
    Assignee: Ferrer Internacional, S.A.
    Inventors: Rafael Foguet Ambros, Lluis Anglada Burniol, Manuel Raga Carreno, Jose A. Ortiz Hernandez, Aurelio Sacristan Munoz, Josep M. Castello Barenys
  • Patent number: 5798361
    Abstract: The present invention relates to new 5H-thiazolo?3,2-a!pyrimidin -5-one derivatives having the formula (I): ##STR1## wherein Ar is phenyl optionally substituted by one or two groups selected from halogen, alkyl having from 1 to 4 carbon atoms, methylendioxy, alkoxy having from 1 to 4 carbon atoms, and trifluoromethyl; and R is a group selected from (a) or (b): ##STR2## as well as their pharmaceutically acceptable addition salts, which are useful in the treatment of psychosis, schizophrenia and anxiety. This invention also discloses methods and intermediates for their preparation and pharmaceutical compositions containing them.
    Type: Grant
    Filed: March 14, 1997
    Date of Patent: August 25, 1998
    Assignee: Ferrer Internacional, S.A.
    Inventors: Rafael Foguet, Lluis Anglada, Aurelio Sacristan, Josep M. Castello, Jose A. Ortiz
  • Patent number: 5736558
    Abstract: The present invention relates to 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives having the formula (I): ##STR1## wherein R is hydrogen or alkyl having 1 to 4 carbon atoms optionally substituted by hydroxyl, as well as their pharmaceutically acceptable addition salts, which are useful in the treatment of psychosis, schizophrenia and anxiety.
    Type: Grant
    Filed: March 14, 1997
    Date of Patent: April 7, 1998
    Assignee: Ferrer Internacional, S.A.
    Inventors: Rafael Foguet, Lluis Anglada, Jordi Bolos, Aurelio Sacristan, Josep M. Castello, Jose A. Ortiz
  • Patent number: 4843165
    Abstract: A process is disclosed for preparing a 2,3-dihydro-1H-imidazolylethoxy indene antithrombotic agent and its pharmaceutically acceptable salts.
    Type: Grant
    Filed: December 18, 1987
    Date of Patent: June 27, 1989
    Assignee: Ferrer Internacional S.A.
    Inventors: Rafael Foguet, Ernesto Forne, Aurelio Sacristan, Josep M. Castello, Jose A. Ortiz